Ku is associated with the telomere in mammals (Q22010717)

GOA release 2020-03-11

telomeric DNA binding

1 reference

Proceedings of the National Academy of Sciences of the United States of America

GOA release 2020-03-11

3

E H Blackburn

E H

Blackburn

1 reference

7 February 2023

H L Hsu

1

H L

Hsu

1 reference

7 February 2023

D Gilley

series ordinal

2

author given names

D

author last names

Gilley

1 reference

7 February 2023

D J Chen

series ordinal

4

author given names

D J

author last names

Chen

1 reference

7 February 2023

language of work or name

English

0 references

publication date

26 October 1999

0 references

published in

0 references

volume

96

0 references

issue

22

0 references

page(s)

12454-8

0 references

cites work

Mammalian telomeres end in a large duplex loop

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Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

19 March 2017

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Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Extension of life-span by introduction of telomerase into normal human cells

19 March 2017

1 reference

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Saccharomyces cerevisiae Ku70 potentiates illegitimate DNA double-strand break repair and serves as a barrier to error-prone DNA repair pathways

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Relocalization of telomeric Ku and SIR proteins in response to DNA strand breaks in yeast

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

A mutant with a defect in telomere elongation leads to senescence in yeast

19 March 2017

1 reference

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Regional assignment of a human DNA repair gene (XRCC5) to 2q35 by X-ray hybrid mapping

19 March 2017

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The DNA-binding protein Hdf1p (a putative Ku homologue) is required for maintaining normal telomere length in Saccharomyces cerevisiae

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

7 April 2017

1 reference

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Transcriptional silencing in yeast is associated with reduced nucleosome acetylation

7 April 2017

1 reference

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Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening

7 April 2017

1 reference

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Evidence of a differential organization of chromatin containing terminal or interstitial (TTAGGG)n repeats by in situ digestion with nucleases.

12 September 2017

1 reference

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Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

12 September 2017

1 reference

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ATM-dependent telomere loss in aging human diploid fibroblasts and DNA damage lead to the post-translational activation of p53 protein involving poly(ADP-ribose) polymerase.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

DNA looping by Ku and the DNA-dependent protein kinase

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

DNA double-strand-break sensitivity, DNA replication, and cell cycle arrest phenotypes of Ku-deficient Saccharomyces cerevisiae

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Identification of a Saccharomyces cerevisiae Ku80 homologue: roles in DNA double strand break rejoining and in telomeric maintenance

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Requirement for Ku80 in growth and immunoglobulin V(D)J recombination

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Disruption of DNA-PK in Ku80 mutant xrs-6 and the implications in DNA double-strand break repair

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Mapping Polycomb-repressed domains in the bithorax complex using in vivo formaldehyde cross-linked chromatin

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Telomerase activity in normal and malignant hematopoietic cells

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Mapping protein-DNA interactions in vivo with formaldehyde: evidence that histone H4 is retained on a highly transcribed gene

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Human cells contain a DNA-activated protein kinase that phosphorylates simian virus 40 T antigen, mouse p53, and the human Ku autoantigen

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Absence of p350 subunit of DNA-activated protein kinase from a radiosensitive human cell line

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Functions of poly(ADP-ribose) polymerase in controlling telomere length and chromosomal stability.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Telomeres and double-strand breaks: trying to make ends meet.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Telomerase in cancer: diagnostic, prognostic, and therapeutic implications.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Length control of human telomeres.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

The telomere and telomerase: nucleic acid-protein complexes acting in a telomere homeostasis system. A review.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Growth retardation and leaky SCID phenotype of Ku70-deficient mice.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Isolation of two cell lines from a human malignant glioma specimen differing in sensitivity to radiation and chemotherapeutic drugs

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Effects of Alu insertions on gene function.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Telomerase RNA mutations in Saccharomyces cerevisiae alter telomerase action and reveal nonprocessivity in vivo and in vitro

19 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22947

Yeast Ku as a regulator of chromosomal DNA end structure

29 November 2018

1 reference

12 December 2020

Telomeres--unsticky ends

1 reference

12 December 2020

Elongated Telomeres inscidMice

1 reference

12 December 2020

Telomerase activity in normal leukocytes and in hematologic malignancies

1 reference

12 December 2020

Sequence-specific DNA binding and transcription factor phosphorylation by Ku Autoantigen/DNA-dependent protein kinase. Phosphorylation of Ser-527 of the rat glucocorticoid receptor

1 reference

12 December 2020

Sequence-specific DNA binding by Ku autoantigen and its effects on transcription

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.96.22.12454

7 January 2021