Secreted frizzled-related protein-1 binds directly to Wingless and is a biphasic modulator of Wnt signaling (Q22011203)

positive regulation of transcription, DNA-templated

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Wingless Dmel_CG4889

1 reference

GOA release 2020-03-11

A Uren

1

A

Uren

1 reference

7 February 2023

F Reichsman

2

F

Reichsman

1 reference

7 February 2023

V Anest

3

V

Anest

1 reference

7 February 2023

W G Taylor

4

W G

Taylor

1 reference

7 February 2023

K Muraiso

5

K

Muraiso

1 reference

7 February 2023

D P Bottaro

6

D P

Bottaro

1 reference

7 February 2023

S Cumberledge

7

S

Cumberledge

1 reference

7 February 2023

J S Rubin

8

J S

Journal of Biological Chemistry

Rubin

1 reference

7 February 2023

language of work or name

English

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publication date

11 February 2000

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published in

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volume

275

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page(s)

4374-82

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issue

6

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Secreted int-1 protein is associated with the cell surface

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A new member of the frizzled family from Drosophila functions as a Wingless receptor

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A frizzled homolog functions in a vertebrate Wnt signaling pathway

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A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled

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Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer

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Frzb, a secreted protein expressed in the Spemann organizer, binds and inhibits Wnt-8.

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A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors

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The cysteine-rich frizzled domain of Frzb-1 is required and sufficient for modulation of Wnt signaling

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Glycosaminoglycans can modulate extracellular localization of the wingless protein and promote signal transduction

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The cell-surface proteoglycan Dally regulates Wingless signalling in Drosophila

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Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling.

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Wingless repression of Drosophila frizzled 2 expression shapes the Wingless morphogen gradient in the wing

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A new secreted protein that binds to Wnt proteins and inhibits their activities

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inferred from DOI database lookup

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based on heuristic

How a growth control path takes a wrong turn to cancer

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