Mechanism by which metformin reduces glucose production in type 2 diabetes (Q22241286)

2

M

Krssak

1 reference

7 February 2023

S. Dufour

3

S

Dufour

1 reference

7 February 2023

D. Laurent

4

D

Laurent

1 reference

7 February 2023

V. Lebon

5

V

Lebon

1 reference

7 February 2023

V. Chandramouli

6

V

Chandramouli

1 reference

7 February 2023

S. E. Inzucchi

7

S E

Inzucchi

1 reference

7 February 2023

W. C. Schumann

8

W C

Schumann

1 reference

7 February 2023

K. F. Petersen

9

K F

Petersen

1 reference

7 February 2023

B. R. Landau

10

B R

Landau

1 reference

7 February 2023

G. I. Shulman

11

G I

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Shulman

1 reference

7 February 2023

language of work or name

English

0 references

publication date

December 2000

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published in

Diabetes

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volume

49

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issue

12

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page(s)

2063-2069

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1 reference

Modifications of citric acid cycle activity and gluconeogenesis in streptozotocin-induced diabetes and effects of metformin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Central role of the adipocyte in insulin resistance

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Contributions of net hepatic glycogenolysis and gluconeogenesis to glucose production in cirrhosis.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Mechanism by which glucose and insulin inhibit net hepatic glycogenolysis in humans

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Contributions of gluconeogenesis to glucose production in the fasted state

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Use of 2H2O for estimating rates of gluconeogenesis. Application to the fasted state

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Metabolic effects of metformin in non-insulin-dependent diabetes mellitus

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Quantitation of hepatic glycogenolysis and gluconeogenesis in fasting humans with 13C NMR.

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Increased rate of gluconeogenesis in type II diabetes mellitus. A 13C nuclear magnetic resonance study

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

The roles of insulin and glucagon in the regulation of hepatic glycogen synthesis and turnover in humans

12 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Lilly lecture 1987. The triumvirate: beta-cell, muscle, liver. A collusion responsible for NIDDM.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Splanchnic and leg exchange of glucose, amino acids, and free fatty acids during exercise in diabetes mellitus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Efficacy and metabolic effects of metformin and troglitazone in type II diabetes mellitus.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Metabolic effects of metformin on glucose and lactate metabolism in noninsulin-dependent diabetes mellitus.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Efficacy of metformin in patients with non-insulin-dependent diabetes mellitus. The Multicenter Metformin Study Group.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Effect of metformin on carbohydrate and lipoprotein metabolism in NIDDM patients

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Quantitative comparison of pathways of hepatic glycogen repletion in fed and fasted humans.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Mechanism of metformin action in obese and lean noninsulin-dependent diabetic subjects.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

In vivo evidence for hepatic autoregulation during FFA-stimulated gluconeogenesis in normal humans

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Combined metformin-sulfonylurea treatment of patients with noninsulin-dependent diabetes in fair to poor glycemic control

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus. A randomized, double-blind, placebo-controlled trial.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Efficacy of metformin in type II diabetes: results of a double-blind, placebo-controlled, dose-response trial.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Metformin decreases gluconeogenesis by enhancing the pyruvate kinase flux in isolated rat hepatocytes.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Liver glycogen turnover in fed and fasted humans.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Relationship between hepatic glucose production and fasting plasma glucose concentration in patients with NIDDM.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

A limitation in the use of mass isotopomer distributions to measure gluconeogenesis in fasting humans.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2995498

Direct analysis of 18O in glucose by mass spectrometry☆

29 November 2018

1 reference

12 December 2020

A microfluorometric method for the determination of free fatty acids in plasma

1 reference

12 December 2020

Acute antihyperglycemic mechanisms of metformin in NIDDM. Evidence for suppression of lipid oxidation and hepatic glucose production

1 reference

12 December 2020

Validation of 13C NMR measurements of liver glycogen in vivo

1 reference

12 December 2020

Limitations of the mass isotopomer distribution analysis of glucose to study gluconeogenesis. Heterogeneity of glucose labeling in incubated hepatocytes

1 reference

12 December 2020

A critical evaluation of mass isotopomer distribution analysis of gluconeogenesis in vivo

1 reference

12 December 2020

Limitations of the mass isotopomer distribution analysis of glucose to study gluconeogenesis. Substrate cycling between glycerol and triose phosphates in liver

1 reference

12 December 2020

The role of fatty acids in mediating the effects of peripheral insulin on hepatic glucose production in the conscious dog

1 reference

12 December 2020

Effects of metformin on lactate uptake and gluconeogenesis in the perfused rat liver

1 reference

12 December 2020

10.2337/DIABETES.49.12.2063

Identifiers

DOI

1 reference

1274001

1274001

1 reference

1 reference

1 reference