Lewy Body Pathology in Alzheimer's Disease (Q22241400)

30 July 2017

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title

Lewy Body Pathology in Alzheimer's Disease (English)

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Lewy body pathology in Alzheimer's disease (English)

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30 July 2017

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Paul T. Kotzbauer

1

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John Q. Tojanowski

2

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Virginia M. V. Lee

3

author given names

Virginia M.-Y.

author last names

Lee

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Dimensions Publication ID

Dimensions

1018385471

7 February 2023

Kotzbauer PT

1

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30 July 2017

Trojanowsk JQ

2

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30 July 2017

Lee VM

3

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30 July 2017

2001

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1 October 2001

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Journal of Molecular Neuroscience

30 July 2017

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Crossref

30 July 2017

17

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30 July 2017

2

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30 July 2017

225-232

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Widespread occurrence of alpha-synuclein/NACP-immunoreactive neuronal inclusions in juvenile and adult-onset Hallervorden-Spatz disease with Lewy bodies

30 July 2017

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12 December 2020

alpha-Synuclein shares physical and functional homology with 14-3-3 proteins

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12 December 2020

Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease

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12 December 2020

Clinical and neuropathological correlates of dementia with Lewy bodies.

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12 December 2020

Enhanced vulnerability to oxidative stress by alpha-synuclein mutations and C-terminal truncation

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12 December 2020

Alpha-synuclein cortical Lewy bodies correlate with dementia in Parkinson's disease

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12 December 2020

Both familial Parkinson's disease mutations accelerate alpha-synuclein aggregation

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12 December 2020

Membrane association and protein conformation of alpha-synuclein in intact neurons. Effect of Parkinson's disease-linked mutations

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12 December 2020

The role of mitochondrial dysfunction and neuronal nitric oxide in animal models of neurodegenerative diseases

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12 December 2020

Neuropathological diagnoses in elderly patients in Oslo: Alzheimer's disease, Lewy body disease, vascular lesions.

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12 December 2020

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

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12 December 2020

Lewy body in neurodegeneration with brain iron accumulation type 1 is immunoreactive for alpha-synuclein.

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12 December 2020

The A53T alpha-synuclein mutation increases iron-dependent aggregation and toxicity

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12 December 2020

Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes

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12 December 2020

Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

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12 December 2020

The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease.

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12 December 2020

Overexpression of human alpha-synuclein causes dopamine neuron death in rat primary culture and immortalized mesencephalon-derived cells.

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12 December 2020

Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease

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12 December 2020

Alpha-synuclein accumulates in Lewy bodies in Parkinson's disease and dementia with Lewy bodies but not in Alzheimer's disease beta-amyloid plaque cores.

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12 December 2020

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

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12 December 2020

Neural expression profile of alpha-synuclein in developing human cortex.

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12 December 2020

Dementia with Lewy bodies

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12 December 2020

Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies.

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12 December 2020

Antibodies to alpha-synuclein detect Lewy bodies in many Down's syndrome brains with Alzheimer's disease.

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12 December 2020

Dopaminergic loss and inclusion body formation in alpha-synuclein mice: implications for neurodegenerative disorders

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12 December 2020

The Lewy body variant of Alzheimer's disease: a clinical and pathologic entity

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12 December 2020

Accumulation of alpha-synuclein in autonomic nerves in pure autonomic failure

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12 December 2020

Plaque-only Alzheimer disease is usually the lewy body variant, and vice versa.

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12 December 2020

Synucleins are developmentally expressed, and alpha-synuclein regulates the size of the presynaptic vesicular pool in primary hippocampal neurons

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12 December 2020

The frequency of Lewy bodies in a consecutive autopsy series

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12 December 2020

Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

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12 December 2020

Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease.

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12 December 2020

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12 December 2020

alpha-synuclein promotes mitochondrial deficit and oxidative stress

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12 December 2020

Purification and characterization of Lewy bodies from the brains of patients with diffuse Lewy body disease

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12 December 2020

Effects of the mutations Ala30 to Pro and Ala53 to Thr on the physical and morphological properties of alpha-synuclein protein implicated in Parkinson's disease

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12 December 2020

Regulation of phospholipase D2: selective inhibition of mammalian phospholipase D isoenzymes by alpha- and beta-synucleins

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12 December 2020

Origin and functional consequences of the complex I defect in Parkinson's disease

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12 December 2020

Wild-type but not Parkinson's disease-related ala-53 --> Thr mutant alpha -synuclein protects neuronal cells from apoptotic stimuli

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12 December 2020

Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease

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12 December 2020

Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons.

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12 December 2020

Comparison of Lewy body variant of Alzheimer's disease with pure Alzheimer's disease: Consortium to Establish a Registry for Alzheimer's Disease, Part XIX.

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12 December 2020

Quantitative neuropathological study of Alzheimer-type pathology in the hippocampus: Comparison of senile dementia of Alzheimer type, senile dementia of Lewy body type, Parkinson's disease and non-demented elderly control patients

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12 December 2020

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12 December 2020

Mitochondrial complex I deficiency in Parkinson's disease

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12 December 2020

Alzheimer's disease: genes, proteins, and therapy

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12 December 2020

beta-Amyloid precursor protein metabolites and loss of neuronal Ca2+ homeostasis in Alzheimer's disease.

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12 December 2020

Inflammation and Alzheimer's disease pathogenesis

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12 December 2020

alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

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12 December 2020

Pure autonomic failure in association with human alpha-synucleinopathy

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12 December 2020

Effect of the overexpression of wild-type or mutant alpha-synuclein on cell susceptibility to insult

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12 December 2020

Intraneuronal filamentous tau protein and alpha-synuclein deposits in neurodegenerative diseases.

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12 December 2020

Review: Alzheimer's amyloid beta-peptide-associated free radical oxidative stress and neurotoxicity

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12 December 2020

Convergence of Lewy bodies and neurofibrillary tangles in amygdala neurons of Alzheimer's disease and Lewy body disorders

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12 December 2020

Non-Abeta component of Alzheimer's disease amyloid (NAC) revisited. NAC and alpha-synuclein are not associated with Abeta amyloid.

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12 December 2020

Clinical-neuropathological correlations in Alzheimer's disease and related dementias

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12 December 2020

NACP, a protein implicated in Alzheimer's disease and learning, is natively unfolded

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12 December 2020

Glial cytoplasmic inclusions in white matter oligodendrocytes of multiple system atrophy brains contain insoluble alpha-synuclein.

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12 December 2020

Sensitization of neuronal cells to oxidative stress with mutated human alpha-synuclein

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12 December 2020

Alpha-synuclein in Lewy bodies

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12 December 2020

Mutant and wild type human alpha-synucleins assemble into elongated filaments with distinct morphologies in vitro

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12 December 2020

A Drosophila model of Parkinson's disease

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12 December 2020

Expression pattern of synucleins (non-Abeta component of Alzheimer's disease amyloid precursor protein/alpha-synuclein) during murine brain development

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12 December 2020

Mechanisms of MPTP toxicity.

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12 December 2020

Lewy bodies in Alzheimer's disease: a neuropathological review of 145 cases using alpha-synuclein immunohistochemistry.

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12 December 2020

A 10-year study of the incidence of and factors predicting dementia in Parkinson's disease.

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12 December 2020

Filamentous alpha-synuclein inclusions link multiple system atrophy with Parkinson's disease and dementia with Lewy bodies.

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12 December 2020

Alpha-synuclein immunoreactivity is present in axonal swellings in neuroaxonal dystrophy and acute traumatic brain injury

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12 December 2020

Ubiquitin carboxyl-terminal hydrolase (PGP 9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative diseases.

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12 December 2020

The inflammatory response system of brain: implications for therapy of Alzheimer and other neurodegenerative diseases

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12 December 2020

Neuropathology of Parkinson's disease

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12 December 2020

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12 December 2020

Delayed localization of synelfin (synuclein, NACP) to presynaptic terminals in cultured rat hippocampal neurons

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12 December 2020

Abnormalities of the electron transport chain in idiopathic Parkinson's disease

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12 December 2020

The Lewy-body variant of Alzheimer's disease. Clinical and pathological findings

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12 December 2020

Lewy Bodies of Parkinson's Disease Contain Neurofilament Antigens

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12 December 2020

Immunocytochemical co-localization of the proteasome in ubiquitinated structures in neurodegenerative diseases and the elderly.

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12 December 2020

Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

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12 December 2020

Predictors of progression in patients with AD and Lewy bodies

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12 December 2020

Dityrosine cross-linking promotes formation of stable alpha -synuclein polymers. Implication of nitrative and oxidative stress in the pathogenesis of neurodegenerative synucleinopathies

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12 December 2020

Identifiers

DOI

10.1385/JMN:17:2:225

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Dimensions Publication ID

30 July 2017

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