Transducin-like enhancer of split proteins, the human homologs of Drosophila groucho, interact with hepatic nuclear factor 3beta (Q22253477)

GOA release 2020-03-11

author

Stefano Stifani

1 reference

ORCID Public Data File 2021

J C Wang

1

J C

Wang

1 reference

7 February 2023

M Waltner-Law

2

M

Waltner-Law

1 reference

7 February 2023

K Yamada

3

K

Yamada

1 reference

7 February 2023

H Osawa

4

H

Osawa

1 reference

7 February 2023

S Stifani

5

0 references

D K Granner

6

D K

Journal of Biological Chemistry

Granner

1 reference

7 February 2023

language of work or name

English

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publication date

16 June 2000

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published in

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volume

275

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issue

24

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page(s)

18418-23

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cites work

Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genes

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Overproduction of a truncated hepatocyte nuclear factor 3 protein inhibits expression of liver-specific genes in hepatoma cells

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Targeted disruption of the gene encoding hepatocyte nuclear factor 3gamma results in reduced transcription of hepatocyte-specific genes

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Hepatic nuclear factor 3- and hormone-regulated expression of the phosphoenolpyruvate carboxykinase and insulin-like growth factor-binding protein 1 genes

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Activation of the tyrosine aminotransferase gene is dependent on synergy between liver-specific and hormone-responsive elements

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Hepatocyte nuclear factor 3beta is involved in pancreatic beta-cell-specific transcription of the pdx-1 gene

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The lung-specific surfactant protein B gene promoter is a target for thyroid transcription factor 1 and hepatocyte nuclear factor 3, indicating common factors for organ-specific gene expression along the foregut axis

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HNF-3 beta is essential for node and notochord formation in mouse development

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HNF-3 beta as a regulator of floor plate development

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Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head

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Hepatocyte nuclear factor 3 beta contains two transcriptional activation domains, one of which is novel and conserved with the Drosophila fork head protein

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Control of apolipoprotein AI gene expression through synergistic interactions between hepatocyte nuclear factors 3 and 4.

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Members of the nuclear factor 1 family and hepatocyte nuclear factor 4 bind to overlapping sequences of the L-II element on the rat pyruvate kinase L gene promoter and regulate its expression

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SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4.

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Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

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Pancreatic beta-cell-type-specific expression of the rat insulin II gene is controlled by positive and negative cellular transcriptional elements

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Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins

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Groucho proteins: transcriptional corepressors for specific subsets of DNA-binding transcription factors in vertebrates and invertebrates.

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Products of the grg (Groucho-related gene) family can dimerize through the amino-terminal Q domain

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A role for Groucho tetramerization in transcriptional repression

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Transducin-like Enhancer of split 2, a mammalian homologue of Drosophila Groucho, acts as a transcriptional repressor, interacts with Hairy/Enhancer of split proteins, and is expressed during neuronal development

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The Xenopus Wnt effector XTcf-3 interacts with Groucho-related transcriptional repressors

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PRDI-BF1/Blimp-1 repression is mediated by corepressors of the Groucho family of proteins

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Identification of a sequence in the PEPCK gene that mediates a negative effect of insulin on transcription

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Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein

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The WRPW motif of the hairy-related basic helix-loop-helix repressor proteins acts as a 4-amino-acid transcription repression and protein-protein interaction domain

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A conserved motif in goosecoid mediates groucho-dependent repression in Drosophila embryos

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Transcriptional repression by AML1 and LEF-1 is mediated by the TLE/Groucho corepressors

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Groucho acts as a corepressor for a subset of negative regulators, including Hairy and Engrailed

21 January 2018

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Conversion of dorsal from an activator to a repressor by the global corepressor Groucho

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Drosophila Tcf and Groucho interact to repress Wingless signalling activity.

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Signal-specific co-activator domain requirements for Pit-1 activation

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Combinatorial expression patterns of individual TLE proteins during cell determination and differentiation suggest non-redundant functions for mammalian homologs of Drosophila Groucho.

21 January 2018

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Affinity for the nuclear compartment and expression during cell differentiation implicate phosphorylated Groucho/TLE1 forms of higher molecular mass in nuclear functions

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M910211199

TLE, the Human Homolog of Groucho, Interacts with AML1 and Acts as a Repressor of AML1-Induced Transactivation

21 January 2018

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Hepatic nuclear factor 3 is an accessory factor required for the stimulation of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids

21 January 2018

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The Phosphoenolpyruvate Carboxykinase Gene Glucocorticoid Response Unit: Identification of the Functional Domains of Accessory Factors HNF3 (Hepatic Nuclear Factor-3 ) and HNF4 and the Necessity of Proper Alignment of Their Cognate Binding Sites

21 January 2018

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The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M910211199

No discrete complexes containing DNA polymerase alpha activity can be solubilized from the heat-stabilized nuclear matrix prepared from HeLa S3 cells

21 January 2018

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inferred from DOI database lookup

7 January 2021

based on heuristic

In vivo protein-DNA interactions on a glucocorticoid response unit of a liver-specific gene: hormone-induced transcription factor binding to constitutively open chromatin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M910211199

inferred from DOI database lookup

7 January 2021

based on heuristic

Site-specific inhibition of RNA polymerase II preinitiation complex assembly by human cytomegalovirus IE86 protein.

1 reference

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