Homeostatic modulation of cell surface KDR and Flt1 expression and expression of the vascular endothelial cell growth factor (VEGF) receptor mRNAs by VEGF (Q22253478)

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English	Homeostatic modulation of cell surface KDR and Flt1 expression and expression of the vascular endothelial cell growth factor (VEGF) receptor mRNAs by VEGF	scientific article

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scholarly article

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Homeostatic modulation of cell surface KDR and Flt1 expression and expression of the vascular endothelial cell growth factor (VEGF) receptor mRNAs by VEGF (English)

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Fms related receptor tyrosine kinase 1

1 reference

GOA release 2020-03-11

positive regulation of cell population proliferation

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GOA release 2020-03-11

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based on heuristic

inferred from title

author name string

D Wang

1

author given names

D

author last names

Wang

1 reference

28 March 2023

D B Donner

2

author given names

D B

author last names

Donner

1 reference

28 March 2023

R S Warren

3

author given names

R S

author last names

Warren

1 reference

28 March 2023

language of work or name

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publication date

26 May 2000

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Journal of Biological Chemistry

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275

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21

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15905-11

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Mechanisms of angiogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001847200

21 January 2018

The biology of vascular endothelial growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001847200

21 January 2018

Vascular permeability factor: A unique regulator of blood vessel function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001847200

21 January 2018

Molecular and biological properties of the vascular endothelial growth factor family of proteins

1 reference

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Isolation and characterization of a vascular endothelial cell mitogen produced by pituitary-derived folliculo stellate cells

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Vascular endothelial growth factor is a secreted angiogenic mitogen

1 reference

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Vascular permeability factor (vascular endothelial growth factor) gene is expressed differentially in normal tissues, macrophages, and tumors

1 reference

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Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis

1 reference

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Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis

1 reference

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Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo.

1 reference

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Regulation by vascular endothelial growth factor of human colon cancer tumorigenesis in a mouse model of experimental liver metastasis

1 reference

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Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

1 reference

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The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

1 reference

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Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium

1 reference

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A receptor tyrosine kinase cDNA isolated from a population of enriched primitive hematopoietic cells and exhibiting close genetic linkage to c-kit

1 reference

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Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

1 reference

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21 January 2018

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1 reference

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Interaction of vasculotropin/vascular endothelial cell growth factor with human umbilical vein endothelial cells: Binding, internalization, degradation, and biological effects

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Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

1 reference

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Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

1 reference

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Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors. Generation of receptor-selective VEGF variants by site-directed mutagenesis

1 reference

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21 January 2018

Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation.

1 reference

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21 January 2018

The phosphorylated 1169-tyrosine containing region of flt-1 kinase (VEGFR-1) is a major binding site for PLCgamma

1 reference

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21 January 2018

Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth

1 reference

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Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001847200

21 January 2018

The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001847200

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The 230 kDa mature form of KDR/Flk-1 (VEGF receptor-2) activates the PLC-gamma pathway and partially induces mitotic signals in NIH3T3 fibroblasts

1 reference

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21 January 2018

Identification of vascular endothelial growth factor receptor-1 tyrosine phosphorylation sites and binding of SH2 domain-containing molecules

1 reference

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21 January 2018

VRAP is an adaptor protein that binds KDR, a receptor for vascular endothelial cell growth factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001847200

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Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria

1 reference

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21 January 2018

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1 reference

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21 January 2018

Homologous up-regulation of KDR/Flk-1 receptor expression by vascular endothelial growth factor in vitro.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001847200

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Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

1 reference

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Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

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Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

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Overexpression of vascular permeability factor/vascular endothelial growth factor and its receptors in psoriasis

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Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders

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Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

1 reference

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Regulation of VEGF/VPF expression in tumor cells: consequences for tumor growth and metastasis

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Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression

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Induction of vascular endothelial growth factor by insulin-like growth factor 1 in colorectal carcinoma

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Coordinated induction of VEGF receptors in mesenchymal cell types during rat hepatic wound healing

1 reference

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Increased gene expression for VEGF and the VEGF receptors KDR/Flk and Flt in lungs exposed to acute or to chronic hypoxia. Modulation of gene expression by nitric oxide

1 reference

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21 January 2018

Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M001847200

21 January 2018

p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells.

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Scatter factor induces blood vessel formation in vivo

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Tumor necrosis factor-alpha regulates expression of vascular endothelial growth factor receptor-2 and of its co-receptor neuropilin-1 in human vascular endothelial cells.

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Downregulation of vascular endothelial growth factor receptors by tumor necrosis factor-alpha in cultured human vascular endothelial cells

1 reference

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Transforming growth factor beta 1 down-regulates vascular endothelial growth factor receptor 2/flk-1 expression in vascular endothelial cells.

1 reference

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Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

1 reference

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21 January 2018

The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities

1 reference

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Expression of transforming growth factor alpha messenger RNA in the normal and neoplastic gastro-intestinal tract

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Vascular endothelial growth factor and glioma angiogenesis: coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo regulatory mechanisms

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MAP kinases, phosphatidylinositol 3-kinase, and p70 S6 kinase mediate the mitogenic response of human endothelial cells to vascular endothelial growth factor

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Regulation of vascular endothelial growth factor expression in cultured keratinocytes. Implications for normal and impaired wound healing

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Tumor necrosis factor employs a protein-tyrosine phosphatase to inhibit activation of KDR and vascular endothelial cell growth factor-induced endothelial cell proliferation

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1 reference

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Functional upregulation of the vascular endothelial growth factor receptor KDR by hypoxia

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7 January 2021

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Comparative analysis of vascular endothelial growth factor receptors on retinal and aortic vascular endothelial cells

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10.1074/JBC.M001847200

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