The polycystic kidney disease protein PKD2 interacts with Hax-1, a protein associated with the actin cytoskeleton (Q22253865)

GOA release 2020-03-11

HCLS1 associated X-1

1 reference

polycystic kidney disease

GOA release 2020-03-11

1 reference

A R Gallagher

1

A R

Gallagher

1 reference

7 February 2023

A Cedzich

2

A

Cedzich

1 reference

7 February 2023

N Gretz

3

N

Gretz

1 reference

7 February 2023

S Somlo

4

S

Somlo

1 reference

7 February 2023

R Witzgall

5

R

Proceedings of the National Academy of Sciences of the United States of America

Witzgall

1 reference

7 February 2023

language of work or name

English

0 references

publication date

11 April 2000

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published in

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volume

97

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issue

8

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page(s)

4017-22

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cites work

Genes homologous to the autosomal dominant polycystic kidney disease genes (PKD1 and PKD2)

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Specific association of the gene product of PKD2 with the TRPC1 channel

19 March 2017

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Identification of PKD2L, a human PKD2-related gene: tissue-specific expression and mapping to chromosome 10q25

19 March 2017

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Identification of PKDL, a novel polycystic kidney disease 2-like gene whose murine homologue is deleted in mice with kidney and retinal defects

19 March 2017

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Growth factor-dependent phosphorylation of the actin-binding protein cortactin is mediated by the cytoplasmic tyrosine kinase FER

19 March 2017

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Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2

19 March 2017

1 reference

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PKD1 interacts with PKD2 through a probable coiled-coil domain

19 March 2017

1 reference

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HAX-1, a novel intracellular protein, localized on mitochondria, directly associates with HS1, a substrate of Src family tyrosine kinases

19 March 2017

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Reverse two-hybrid and one-hybrid systems to detect dissociation of protein-protein and DNA-protein interactions

19 March 2017

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The product of the EMS1 gene, amplified and overexpressed in human carcinomas, is homologous to a v-src substrate and is located in cell-substratum contact sites

19 March 2017

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Identification of HS1 protein as a major substrate of protein-tyrosine kinase(s) upon B-cell antigen receptor-mediated signaling

19 March 2017

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Cortactin, an 80/85-kilodalton pp60src substrate, is a filamentous actin-binding protein enriched in the cell cortex

19 March 2017

1 reference

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The polycystic kidney disease 1 (PKD1) gene encodes a novel protein with multiple cell recognition domains

19 March 2017

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Isolation and characterization of a novel human gene expressed specifically in the cells of hematopoietic lineage

19 March 2017

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Tight control of gene expression in mammalian cells by tetracycline-responsive promoters

19 March 2017

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High-efficiency transformation of mammalian cells by plasmid DNA

19 March 2017

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The role of tyrosine phosphorylation of cortactin in the locomotion of endothelial cells

19 March 2017

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Progressive kidney degeneration in mice lacking tensin

19 March 2017

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PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein

19 March 2017

1 reference

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Translocation of cortactin to the cell periphery is mediated by the small GTPase Rac1

19 March 2017

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Hierarchical phosphorylation of a 50-kDa protein by protein tyrosine kinases TPK-IIB and C-Fgr, and its identification as HS1 hematopoietic-lineage cell-specific protein

19 March 2017

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Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18134

Identification and characterization of polycystin-2, the PKD2 gene product

27 September 2017

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Cellular activation triggered by the autosomal dominant polycystic kidney disease gene product PKD2

27 September 2017

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The polycystic kidney disease 1 gene product modulates Wnt signaling

27 September 2017

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Linearization of the Bradford protein assay increases its sensitivity: theoretical and experimental studies

27 September 2017

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Isolation of nine gene sequences induced by silica in murine macrophages

27 September 2017

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LckBP1, a proline-rich protein expressed in haematopoietic lineage cells, directly associates with the SH3 domain of protein tyrosine kinase p56lck.

27 September 2017

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The protein tyrosine kinase substrate cortactin is differentially expressed in murine B lymphoid tumors.

27 September 2017

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The rat pkd2 protein assumes distinct subcellular distributions in different organs

27 September 2017

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Overexpression of EMS1/cortactin in NIH3T3 fibroblasts causes increased cell motility and invasion in vitro

30 May 2018

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Molecular determinants of Ca2+ selectivity and ion permeation in L-type Ca2+ channels

30 May 2018

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Murine cortactin is phosphorylated in response to fibroblast growth factor-1 on tyrosine residues late in the G1 phase of the BALB/c 3T3 cell cycle.

30 May 2018

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The membrane topology of human transient receptor potential 3 as inferred from glycosylation-scanning mutagenesis and epitope immunocytochemistry.

30 May 2018

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Crossref

https://api.crossref.org/works/10.1073%2FPNAS.97.8.4017

Tyrosine phosphorylation of cortactin associated with Syk accompanies thromboxane analogue-induced platelet shape change.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.97.8.4017

The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. The European Polycystic Kidney Disease Consortium

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=18134

The PKD1 gene product, "polycystin-1," is a tyrosine-phosphorylated protein that colocalizes with alpha2beta1-integrin in focal clusters in adherent renal epithelia

29 November 2018

1 reference

12 December 2020

1 reference

12 December 2020

Intestinal dysplasia and adenoma in transgenic mice after overexpression of an activated beta-catenin

1 reference

12 December 2020

Progressive impairment of kidneys and reproductive organs in mice lacking Rho GDIalpha

1 reference

12 December 2020

The polycystic kidney disease 1 gene product mediates protein kinase C alpha-dependent and c-Jun N-terminal kinase-dependent activation of the transcription factor AP-1

1 reference

12 December 2020

Somatic inactivation of Pkd2 results in polycystic kidney disease

1 reference

12 December 2020

Autosomal dominant polycystic kidney disease

1 reference

12 December 2020

Polycystic kidney disease: The complete structure of the PKD1 gene and its protein

1 reference

12 December 2020

A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.97.8.4017

7 January 2021