Isolation and functional expression of human COQ3, a gene encoding a methyltransferase required for ubiquinone biosynthesis (Q22253956)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0044596

decaprenyldihydroxybenzoate methyltransferase activity

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0044595

Coenzyme Q3, methyltransferase

1 reference

O-methyltransferase activity

GOA release 2020-03-11

1 reference

Journal of Biological Chemistry

GOA release 2020-03-11

T Jonassen

1

T

Jonassen

1 reference

29 March 2023

C F Clarke

series ordinal

2

author given names

C F

author last names

Clarke

1 reference

29 March 2023

language of work or name

English

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publication date

28 April 2000

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published in

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volume

275

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page(s)

12381-7

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issue

17

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cites work

New concepts on the role of ubiquinone in the mitochondrial respiratory chain

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Antioxidant effects of ubiquinones in microsomes and mitochondria are mediated by tocopherol recycling

21 January 2018

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Prevention of tocopherol-mediated peroxidation in ubiquinol-10-free human low density lipoprotein.

21 January 2018

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Genetic evidence for coenzyme Q requirement in plasma membrane electron transport.

21 January 2018

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Enhanced sensitivity of ubiquinone-deficient mutants of Saccharomyces cerevisiae to products of autoxidized polyunsaturated fatty acids

21 January 2018

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Sensitivity to treatment with polyunsaturated fatty acids is a general characteristic of the ubiquinone-deficient yeast coq mutants.

21 January 2018

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Analysis of the decaprenyl diphosphate synthase (dps) gene in fission yeast suggests a role of ubiquinone as an antioxidant

21 January 2018

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Coenzyme Q10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects

21 January 2018

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Effects of coenzyme Q10 and alpha-tocopherol administration on their tissue levels in the mouse: elevation of mitochondrial alpha-tocopherol by coenzyme Q10.

21 January 2018

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Control of arterial tone after long-term coenzyme Q10 supplementation in senescent rats

21 January 2018

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Widespread occurrence of three sequence motifs in diverse S-adenosylmethionine-dependent methyltransferases suggests a common structure for these enzymes

21 January 2018

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The biosynthesis of ubiquinone: Synthesis and enzymatic modification of biosynthetic precursors

21 January 2018

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Yeast and rat Coq3 and Escherichia coli UbiG polypeptides catalyze both O-methyltransferase steps in coenzyme Q biosynthesis

21 January 2018

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Complementation of coq3 mutant yeast by mitochondrial targeting of the Escherichia coli UbiG polypeptide: evidence that UbiG catalyzes both O-methylation steps in ubiquinone biosynthesis.

21 January 2018

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Cloning of a rat cDNA encoding dihydroxypolyprenylbenzoate methyltransferase by functional complementation of a Saccharomyces cerevisiae mutant deficient in ubiquinone biosynthesis

21 January 2018

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Identification of protein coding regions by database similarity search

21 January 2018

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Characterization of Saccharomyces cerevisiae ubiquinone-deficient mutants

21 January 2018

1 reference

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Cloning and functional expression of AtCOQ3, the Arabidopsis homologue of the yeast COQ3 gene, encoding a methyltransferase from plant mitochondria involved in ubiquinone biosynthesis

21 January 2018

1 reference

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Conservation of the Caenorhabditis elegans timing gene clk-1 from yeast to human: a gene required for ubiquinone biosynthesis with potential implications for aging

21 January 2018

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Isolation and sequencing of the rat Coq7 gene and the mapping of mouse Coq7 to chromosome 7

21 January 2018

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Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.

21 January 2018

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Crystal structure of catechol O-methyltransferase

21 January 2018

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Kinetics of human soluble and membrane-bound catechol O-methyltransferase: a revised mechanism and description of the thermolabile variant of the enzyme

21 January 2018

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General properties and clinical possibilities of new selective inhibitors of catechol O-methyltransferase

21 January 2018

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Coenzyme Q10 levels correlate with the activities of complexes I and II/III in mitochondria from parkinsonian and nonparkinsonian subjects.

21 January 2018

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Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice.

21 January 2018

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A possible role of coenzyme Q10 in the etiology and treatment of Parkinson's disease

21 January 2018

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Muscle coenzyme Q deficiency in familial mitochondrial encephalomyopathy

21 January 2018

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A case of mitochondrial encephalomyopathy associated with a muscle coenzyme Q10 deficiency.

21 January 2018

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Orthologues of the Caenorhabditis elegans longevity gene clk-1 in mouse and human

21 January 2018

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CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

21 January 2018

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Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis

21 January 2018

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The p66shc adaptor protein controls oxidative stress response and life span in mammals

21 January 2018

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Monitoring of ubiquinol-10, ubiquinone-10, carotenoids, and tocopherols in neonatal plasma microsamples using high-performance liquid chromatography with coulometric electrochemical detection

21 January 2018

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7 January 2021

Mitochondrial protein import

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12381

7 January 2021

Coenzyme Q10 treatment improves the tolerance of the senescent myocardium to pacing stress in the rat

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12381

7 January 2021

Aging of C. elegans: mosaics and mechanisms

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https://api.crossref.org/works/10.1074%2FJBC.275.17.12381

7 January 2021

Autoxidation of ubiquinol-6 is independent of superoxide dismutase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12381

7 January 2021

Coenzyme Q6 and iron reduction are responsible for the extracellular ascorbate stabilization at the plasma membrane of Saccharomyces cerevisiae

1 reference

https://api.crossref.org/works/10.1074%2FJBC.275.17.12381

7 January 2021

Restricted uptake of dietary coenzyme Q is in contrast to the unrestricted uptake of alpha-tocopherol into rat organs and cells.

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https://api.crossref.org/works/10.1074%2FJBC.275.17.12381

7 January 2021

Mitochondrial encephalomyopathy with coenzyme Q10 deficiency

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7 January 2021