pRB binds to and modulates the transrepressing activity of the E1A-regulated transcription factor p120E4F (Q22254365)

transcription corepressor activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

5

J Polanowska

J

Polanowska

1 reference

7 February 2023

R Medema

7

R

Medema

1 reference

7 February 2023

L Fajas

1

L

Fajas

1 reference

7 February 2023

C Paul

2

C

Paul

1 reference

7 February 2023

O Zugasti

3

O

Zugasti

1 reference

7 February 2023

L Le Cam

4

L

Le Cam

1 reference

7 February 2023

E Fabbrizio

6

E

Fabbrizio

1 reference

7 February 2023

M L Vignais

8

M L

Vignais

1 reference

7 February 2023

C Sardet

9

C

Proceedings of the National Academy of Sciences of the United States of America

Sardet

1 reference

7 February 2023

language of work or name

English

0 references

publication date

5 July 2000

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published in

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volume

97

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issue

14

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page(s)

7738-43

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cites work

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The adenovirus E1A-regulated transcription factor E4F is generated from the human homolog of nuclear factor phiAP3

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HBP1: a HMG box transcriptional repressor that is targeted by the retinoblastoma family

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A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle

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E2F-4 and E2F-5, two members of the E2F family, are expressed in the early phases of the cell cycle

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Binding of an interferon-inducible protein (p202) to the retinoblastoma protein

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A human protein with homology to Saccharomyces cerevisiae SNF5 interacts with the potential helicase hbrm

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E4F and ATF, two transcription factors that recognize the same site, can be distinguished both physically and functionally: a role for E4F in E1A trans activation

19 March 2017

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Recruitment of the retinoblastoma protein to c-Jun enhances transcription activity mediated through the AP-1 binding site

19 March 2017

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The regulation of E2F by pRB-family proteins

19 March 2017

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Retinoblastoma protein recruits histone deacetylase to repress transcription

19 March 2017

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Physical interaction of the retinoblastoma protein with human D cyclins

19 March 2017

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Inhibition of cell proliferation by p107, a relative of the retinoblastoma protein

19 March 2017

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Retinoblastoma gene product activates expression of the human TGF-β2 gene through transcription factor ATF-2

22 April 2017

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Radiation-induced cell cycle arrest compromised by p21 deficiency

19 March 2017

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Effects of an Rb mutation in the mouse

7 April 2017

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p53 is involved in the p120E4F-mediated growth arrest

7 April 2017

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Inhibition of mammalian cell proliferation by genetically selected peptide aptamers that functionally antagonize E2F activity

27 September 2017

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Suppression of E1A-mediated transformation by the p50E4F transcription factor

27 September 2017

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Timing of cyclin E gene expression depends on the regulated association of a bipartite repressor element with a novel E2F complex.

27 September 2017

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Retardation of cell proliferation after expression of p202 accompanies an increase in p21(WAF1/CIP1).

27 September 2017

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Regulation of differentiation by HBP1, a target of the retinoblastoma protein

27 September 2017

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Growth suppression by an E2F-binding-defective retinoblastoma protein (RB): contribution from the RB C pocket

27 September 2017

1 reference

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Rb binds c-Jun and activates transcription

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16614

Chromosomal location and tissue expression of the gene encoding the adenovirus E1A-regulated transcription factor E4F in humans and mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16614

Mutational analysis of p50E4F suggests that DNA binding activity is mediated through an alternative structure in a zinc finger domain that is regulated by phosphorylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16614

Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth

27 September 2017

1 reference

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Adenovirus E1A-regulated transcription factor p120E4F inhibits cell growth and induces the stabilization of the cdk inhibitor p21WAF1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16614

Arrest of the cell cycle by the tumour-suppressor BRCA1 requires the CDK-inhibitor p21WAF1/CiP1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16614

Mechanism of repression of RNA polymerase I transcription by the retinoblastoma protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16614

Retinoblastoma protein positively regulates terminal adipocyte differentiation through direct interaction with C/EBPs

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16614

Retinoblastoma protein directly interacts with and activates the transcription factor NF-IL6

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16614

Interaction of myogenic factors and the retinoblastoma protein mediates muscle cell commitment and differentiation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16614

Repression of adenovirus E1A enhancer activity by a novel zinc finger-containing DNA-binding protein related to the GLI-Kruppel protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16614

Transcriptional modulation by the adenovirus E1A gene.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16614

Adenovirus E1A: transcription regulation and alteration of cell growth control

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16614

The state of cellular differentiation determines the activity of the adenovirus E1A enhancer element: evidence for negative regulation of enhancer function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16614

Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16614

Identification of an E1A-inducible cellular factor that interacts with regulatory sequences within the adenovirus E4 promoter

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16614

Functional analysis at the Cys706 residue of the retinoblastoma protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16614

Disruption of retinoblastoma protein function by coexpression of its C pocket fragment.

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.130198397

Partial inactivation of the RB product in a family with incomplete penetrance of familial retinoblastoma and benign retinal tumors.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=16614

Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth

29 November 2018

1 reference

12 December 2020

Activation and repression of p21(WAF1/CIP1) transcription by RB binding proteins

1 reference

12 December 2020

Human E2F5 gene is oncogenic in primary rodent cells and is amplified in human breast tumors

1 reference

12 December 2020

DNA-binding activity of the adenovirus-induced E4F transcription factor is regulated by phosphorylation

1 reference

12 December 2020