Transcriptional modulation of the anti-apoptotic protein BCL-XL by the paired box transcription factors PAX3 and PAX3/FKHR (Q22254411)

Forkhead box O1

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Paired box 7

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positive regulation of transcription by RNA polymerase II

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C M Margue

1

Christiane M

Margue

1 reference

7 February 2023

M Bernasconi

series ordinal

2

author given names

Michele

author last names

Bernasconi

1 reference

7 February 2023

F G Barr

series ordinal

3

author given names

Frederic G

author last names

Barr

1 reference

7 February 2023

B W Schäfer

series ordinal

4

author given names

Beat W

author last names

Schäfer

1 reference

Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis

7 February 2023

language of work or name

English

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publication date

8 June 2000

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published in

Oncogene

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volume

19

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page(s)

2921-9

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issue

25

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cites work

1 reference

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The Bcl-2 protein family: arbiters of cell survival

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Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily

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Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma

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Induction of apoptosis in rhabdomyosarcoma cells through down-regulation of PAX proteins.

21 January 2018

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Pax-3 contains domains for transcription activation and transcription inhibition

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Pax genes and organogenesis.

21 January 2018

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Regulation of the forkhead transcription factor FKHR, but not the PAX3-FKHR fusion protein, by the serine/threonine kinase Akt.

21 January 2018

1 reference

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Pax3 inhibits myogenic differentiation of cultured myoblast cells

21 January 2018

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Pax3 modulates expression of the c-Met receptor during limb muscle development

21 January 2018

1 reference

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The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3

21 January 2018

1 reference

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Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma

21 January 2018

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The Pax3-FKHR oncoprotein is unresponsive to the Pax3-associated repressor hDaxx

21 January 2018

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The oncogenic potential of the Pax3-FKHR fusion protein requires the Pax3 homeodomain recognition helix but not the Pax3 paired-box DNA binding domain.

21 January 2018

1 reference

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Pax genes and their roles in cell differentiation and development

21 January 2018

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Ectopic Pax-3 activates MyoD and Myf-5 expression in embryonic mesoderm and neural tissue

21 January 2018

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Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line

21 January 2018

1 reference

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Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments

21 January 2018

1 reference

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Neural tube defects in embryos of diabetic mice: role of the Pax-3 gene and apoptosis.

21 January 2018

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Molecular cloning and characterization of a human PAX-7 cDNA expressed in normal and neoplastic myocytes

21 January 2018

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The hybrid PAX3-FKHR fusion protein of alveolar rhabdomyosarcoma transforms fibroblasts in culture

21 January 2018

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Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

21 January 2018

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Redefining the genetic hierarchies controlling skeletal myogenesis: Pax-3 and Myf-5 act upstream of MyoD.

21 January 2018

1 reference

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Epistatic relationship between Waardenburg syndrome genes MITF and PAX3

21 January 2018

1 reference

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Interaction of the pRB-family proteins with factors containing paired-like homeodomains

21 January 2018

1 reference

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Cooperative dimerization of paired class homeo domains on DNA.

21 January 2018

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The Splotch mutation interferes with muscle development in the limbs

21 January 2018

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7 January 2021

Normal and rearranged PAX3 expression in human rhabdomyosarcoma

1 reference

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7 January 2021

Pax-3, a novel murine DNA binding protein expressed during early neurogenesis.

1 reference

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7 January 2021

Massive cell death of immature hematopoietic cells and neurons in Bcl-x-deficient mice

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7 January 2021

The rise and fall of apoptosis during multistage tumorigenesis: down-modulation contributes to tumor progression from angiogenic progenitors

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7 January 2021

Deficiency in rhabdomyosarcomas of a factor required for MyoD activity and myogenesis

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7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1203607

0 references