lovastatin nonaketide synthase activity (Q22323537)
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Catalysis of the reaction: S-adenosyl-L-methionine(1+) + acetyl-CoA + 18 H(+) + 8 malonyl-CoA + 11 NADPH = S-adenosyl-L-homocysteine + 8 CO(2) + 9 CoA + dihydromonacolin L + 6 H(2)O + 11 NADP(+).
- acyl-CoA:malonyl-CoA C-acyltransferase (decarboxylating, oxoacyl- and enoyl-reducing, thioester-hydrolysing)
- GO:0050637
Language | Label | Description | Also known as |
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English | lovastatin nonaketide synthase activity |
Catalysis of the reaction: S-adenosyl-L-methionine(1+) + acetyl-CoA + 18 H(+) + 8 malonyl-CoA + 11 NADPH = S-adenosyl-L-homocysteine + 8 CO(2) + 9 CoA + dihydromonacolin L + 6 H(2)O + 11 NADP(+). |
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Statements
1 reference
2.3.1.161
1 reference
1 reference
1 February 2021
1 reference
1 February 2021
Identifiers
1 reference
1 reference