Crystallin alpha A (Q22676584)

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mammalian protein found in Homo sapiens
  • human alphaA-crystallin (CRYA1)
  • alpha-crystallin A chain
  • heat shock protein beta-4
  • CRYAA2
  • alpha-crystallin A2 chain
  • crystallin, alpha-1
  • CRYAA
  • LOC102724652
  • HspB4
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Language Label Description Also known as
English
Crystallin alpha A
mammalian protein found in Homo sapiens
  • human alphaA-crystallin (CRYA1)
  • alpha-crystallin A chain
  • heat shock protein beta-4
  • CRYAA2
  • alpha-crystallin A2 chain
  • crystallin, alpha-1
  • CRYAA
  • LOC102724652
  • HspB4

Statements

molecular function
protein binding
determination method
IPI
11 references
retrieved
9 May 2019
stated in
Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis
GOA
curator
UniProt
UniProt protein ID
P02489
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489
determination method
IPI
retrieved
9 May 2019
stated in
Widespread macromolecular interaction perturbations in human genetic disorders
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489
determination method
IPI
retrieved
9 May 2019
stated in
The eye lens chaperone alpha-crystallin forms defined globular assemblies.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489
determination method
IPI
retrieved
9 May 2019
stated in
Temperature-dependent structural and functional properties of a mutant (F71L) αA-crystallin: molecular basis for early onset of age-related cataract
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489
determination method
IPI
retrieved
9 May 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489
determination method
IPI
retrieved
9 May 2019
stated in
Alteration of protein-protein interactions of congenital cataract crystallin mutants
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489
determination method
IPI
retrieved
9 May 2019
stated in
Detection of protein-protein interactions among lens crystallins in a mammalian two-hybrid system assay
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489
determination method
IPI
retrieved
9 May 2019
stated in
Binding determinants of the small heat shock protein, αB-crystallin: recognition of the 'IxI' motif
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489
determination method
IPI
retrieved
9 May 2019
stated in
The polydispersity of αB-crystallin is rationalized by an interconverting polyhedral architecture
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489
determination method
IPI
retrieved
9 May 2019
stated in
Human alphaA- and alphaB-crystallins bind to Bax and Bcl-X(S) to sequester their translocation during staurosporine-induced apoptosis
GOA
curator
HUGO Gene Nomenclature Committee
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489
determination method
IPI
retrieved
9 May 2019
stated in
Role of the C-terminal extensions of alpha-crystallins. Swapping the C-terminal extension of alpha-crystallin to alphaB-crystallin results in enhanced chaperone activity
GOA
curator
Critical Assessment of Protein Function Annotation
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P02489
determination method
IPI
cell component
biological process

Identifiers

 
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