Heat shock protein 1B (Q22678756)

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mammalian protein found in Mus musculus

heat shock 70 kDa protein 1B
heat shock protein 70.1
HSP70.1
Hspa1b
68 kDa heat shock protein
heat shock 70kDa protein 1B
heat shock 70 kDa protein 1
heat shock protein, 70 kDa 1

Language	Label	Description	Also known as
English	Heat shock protein 1B	mammalian protein found in Mus musculus	heat shock 70 kDa protein 1B heat shock protein 70.1 HSP70.1 Hspa1b 68 kDa heat shock protein heat shock 70kDa protein 1B heat shock 70 kDa protein 1 heat shock protein, 70 kDa 1

Statements

1 reference

25 May 2022

UniProt protein ID

1 reference

19 January 2017

UniProt protein ID

Heat shock protein 70kD, peptide-binding domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17879

Heat shock protein 70kD, C-terminal domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17879

Heat shock protein 70 family

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17879

Heat shock protein 70, conserved site, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

molecular function

nucleotide binding

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

protein binding

determination method

5 references

14 February 2019

A mouse homologue of the Drosophila tumor suppressor l(2)tid gene defines a novel Ras GTPase-activating protein (RasGAP)-binding protein

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

14 February 2019

A DnaJ protein, apobec-1-binding protein-2, modulates apolipoprotein B mRNA editing

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

14 February 2019

Isolation of Bcl-2 binding proteins that exhibit homology with BAG-1 and suppressor of death domains protein

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

14 February 2019

The Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cells

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

14 February 2019

Hsp70 inhibits lipopolysaccharide-induced NF-kappaB activation by interacting with TRAF6 and inhibiting its ubiquitination

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

determination method

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17879&geneProductId=UniProtKB:P17879

determination method

ATPase activity

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

heat shock protein binding

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

ubiquitin protein ligase binding

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

protein folding chaperone activity

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

unfolded protein binding

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

misfolded protein binding

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

determination method

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17879&geneProductId=UniProtKB:P17879

determination method

zona pellucida receptor complex

determination method

1 reference

14 February 2019

The chaperonin containing TCP1 complex (CCT/TRiC) is involved in mediating sperm-oocyte interaction

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

determination method

1 reference

14 February 2019

The chaperonin containing TCP1 complex (CCT/TRiC) is involved in mediating sperm-oocyte interaction

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

mitochondrial matrix

determination method

1 reference

14 February 2019

MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

intracellular anatomical structure

determination method

1 reference

10 September 2018

Function and regulation of heat shock factor 2 during mouse embryogenesis

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17879&geneProductId=UniProtKB:P17879

determination method

determination method

3 references

14 February 2019

Dual specificity phosphatases 18 and 21 target to opposing sides of the mitochondrial inner membrane

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

14 February 2019

MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

14 February 2019

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

microtubule organizing center

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

COP9 signalosome

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

protein-containing complex

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

biological process

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

determination method

1 reference

14 February 2019

Heat-shock protein 70 attenuates nitric oxide-induced apoptosis in RAW macrophages by preventing cytochrome c release

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

negative regulation of apoptotic process

determination method

1 reference

14 February 2019

Heat-shock protein 70 attenuates nitric oxide-induced apoptosis in RAW macrophages by preventing cytochrome c release

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

response to heat

determination method

1 reference

14 February 2019

Analysis of HSF4 binding regions reveals its necessity for gene regulation during development and heat shock response in mouse lenses

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

binding of sperm to zona pellucida

determination method

1 reference

14 February 2019

The chaperonin containing TCP1 complex (CCT/TRiC) is involved in mediating sperm-oocyte interaction

Mouse Genome Informatics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

protein refolding

determination method

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17879&geneProductId=UniProtKB:P17879

determination method

positive regulation of microtubule nucleation

determination method

1 reference

14 February 2019

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

regulation of mitotic spindle assembly

determination method

1 reference

27 March 2018

UniProt protein ID

http://www.ebi.ac.uk/QuickGO/annotations?protein=P17879&geneProductId=UniProtKB:P17879

determination method

response to unfolded protein

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

positive regulation of proteasomal ubiquitin-dependent protein catabolic process

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

cellular response to heat

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

Unfolded Protein Response

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

chaperone cofactor-dependent protein refolding

determination method

1 reference

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P17879

determination method

Heat shock protein 70, conserved site

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/P17879

Identifiers

RefSeq protein ID

1 reference

20 March 2022

UniProt protein ID

1 reference

25 May 2022

UniProt protein ID

Ensembl protein ID

ENSMUSP00000133815

1 reference

ensembl Release 106

Ensembl protein ID

ENSMUSP00000133815

Sitelinks

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Multilingual sites(0 entries)

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