DNA methyltransferase 3 alpha (Q22680017)

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mammalian protein found in Homo sapiens
  • DNMT3A
  • M.HsaIIIA
  • DNA (cytosine-5)-methyltransferase 3A
  • DNA cytosine methyltransferase 3A2
  • DNA MTase HsaIIIA
  • DNA methyltransferase HsaIIIA
  • DNA (cytosine-5-)-methyltransferase 3 alpha
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Language Label Description Also known as
English
DNA methyltransferase 3 alpha
mammalian protein found in Homo sapiens
  • DNMT3A
  • M.HsaIIIA
  • DNA (cytosine-5)-methyltransferase 3A
  • DNA cytosine methyltransferase 3A2
  • DNA MTase HsaIIIA
  • DNA methyltransferase HsaIIIA
  • DNA (cytosine-5-)-methyltransferase 3 alpha

Statements

molecular function
protein binding
determination method
IPI
11 references
retrieved
8 April 2019
stated in
Structure of Dnmt3a bound to Dnmt3L suggests a model for de novo DNA methylation
GOA
curator
UniProt
UniProt protein ID
Q9Y6K1
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6K1
determination method
IPI
retrieved
8 April 2019
stated in
Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6K1
determination method
IPI
retrieved
8 April 2019
stated in
Recruitment of the de novo DNA methyltransferase Dnmt3a by Kaposi's sarcoma-associated herpesvirus LANA
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6K1
determination method
IPI
retrieved
8 April 2019
stated in
Structural insight into autoinhibition and histone H3-induced activation of DNMT3A
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6K1
determination method
IPI
retrieved
8 April 2019
stated in
Dnmt3L antagonizes DNA methylation at bivalent promoters and favors DNA methylation at gene bodies in ESCs
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6K1
determination method
IPI
retrieved
8 April 2019
stated in
The Polycomb group protein EZH2 directly controls DNA methylation
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6K1
determination method
IPI
retrieved
8 April 2019
stated in
A proteome-scale map of the human interactome network
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6K1
determination method
IPI
retrieved
8 April 2019
stated in
The histone methyltransferase SETDB1 and the DNA methyltransferase DNMT3A interact directly and localize to promoters silenced in cancer cells
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6K1
determination method
IPI
retrieved
8 April 2019
stated in
Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6K1
determination method
IPI
retrieved
8 April 2019
stated in
cAMP-responsive element modulator (CREM)α protein signaling mediates epigenetic remodeling of the human interleukin-2 gene: implications in systemic lupus erythematosus
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6K1
determination method
IPI
retrieved
8 April 2019
stated in
PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.
GOA
curator
IntAct protein interaction database
reference URL
http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q9Y6K1
determination method
IPI
cell component
biological process

Identifiers

 
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                    Retrieved from "https://www.wikidata.org/w/index.php?title=Q22680017&oldid=2023045152"