Telomeric repeat binding factor 2 (Q22680121)

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O35144

Telomere repeat-binding factor, dimerisation domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O35144

Homeobox-like domain superfamily

1 reference

InterPro Release 71.0

http://www.ebi.ac.uk/interpro/protein/O35144

SANT/Myb domain, protein family

1 reference

Telomeric repeat-binding factor 2, Rap1-binding domain, protein family

1 reference

Myb domain, protein family

1 reference

Telomere repeat-binding factor, dimerisation domain, protein family

1 reference

1 reference

25 May 2022

1 reference

25 May 2022

3 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

double-stranded telomeric DNA binding

1 reference

9 August 2016

protein homodimerization activity

4 references

9 August 2016

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

telomeric DNA binding

5 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

HOT1 is a mammalian direct telomere repeat-binding protein contributing to telomerase recruitment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

1 reference

9 August 2016

protein C-terminus binding

2 references

9 August 2016

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

6 references

9 August 2016

retrieved

14 February 2019

Loss of Rap1 induces telomere recombination in the absence of NHEJ or a DNA damage signal

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

Telomere-independent Rap1 is an IKK adaptor and regulates NF-kappaB-dependent gene expression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

Apollo contributes to G overhang maintenance and protects leading-end telomeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

Mammalian DNA2 helicase/nuclease cleaves G-quadruplex DNA and is required for telomere integrity

IntAct protein interaction database

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

G-rich strand telomeric DNA binding

IPI

1 reference

9 August 2016

protein-containing complex binding

1 reference

9 August 2016

double-stranded telomeric DNA binding

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

Human telomeres contain two distinct Myb-related proteins, TRF1 and TRF2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

Mouse pachytene checkpoint 2 (trip13) is required for completing meiotic recombination but not synapsis

cell component

male germ cell nucleus

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

1 reference

16 September 2017

http://www.ebi.ac.uk/QuickGO/annotations?protein=O35144&geneProductId=UniProtKB:O35144

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

3 references

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

nuclear telomere cap complex

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

telomere maintenance via telomerase

biological process

1 reference

9 August 2016

protection from non-homologous end joining at telomere

1 reference

9 August 2016

2 references

9 August 2016

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

regulation of telomere maintenance

1 reference

9 August 2016

negative regulation of telomere maintenance via recombination

1 reference

9 August 2016

negative regulation of gene expression

2 references

9 August 2016

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

negative regulation of beta-galactosidase activity

2 references

9 August 2016

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

protein localization to chromosome, telomeric region

1 reference

9 August 2016

positive regulation of telomere maintenance

3 references

9 August 2016

retrieved

14 February 2019

DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

negative regulation of telomere capping

IDA

2 references

9 August 2016

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

positive regulation of gene expression

2 references

9 August 2016

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

positive regulation of nitric-oxide synthase activity

2 references

9 August 2016

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

negative regulation of t-circle formation

2 references

9 August 2016

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

2 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

negative regulation of telomere maintenance

2 references

9 August 2016

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

5 references

9 August 2016

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

Dysfunctional mammalian telomeres join with DNA double-strand breaks

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

regulation of telomere maintenance via telomerase

1 reference

9 August 2016

negative regulation of cellular senescence

2 references

9 August 2016

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

telomeric loop formation

1 reference

9 August 2016

RNA-dependent DNA biosynthetic process

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

anterograde axonal transport

1 reference

14 February 2019

Novel RNA- and FMRP-binding protein TRF2-S regulates axonal mRNA transport and presynaptic plasticity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

IMP

telomeric loop formation

3 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

protection from non-homologous end joining at telomere

IBA

7 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

Apollo contributes to G overhang maintenance and protects leading-end telomeres

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

Super-resolution fluorescence imaging of telomeres reveals TRF2-dependent T-loop formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

DNA processing is not required for ATM-mediated telomere damage response after TRF2 deletion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

14 February 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

negative regulation of telomere maintenance via telomerase

IBA

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

telomeric D-loop disassembly

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

anterograde axonal transport of messenger ribonucleoprotein complex

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

negative regulation of telomere maintenance via telomere lengthening

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144

negative regulation of exonuclease activity

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O35144