The SH4-Unique-SH3-SH2 domains dictate specificity in signaling that differentiate c-Yes from c-Src (Q23915639)

NIOSH Health Effects Laboratory Division

31 December 2023

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HELD

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25 September 2023

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29 March 2020

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29 March 2020

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31 December 2023

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Bing-Hua Jiang

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31 December 2023

author name string

Justin M. Summy

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31 December 2023

Yong Qian

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31 December 2023

Anne Guappone-Koay

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31 December 2023

Amanda Gatesman

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31 December 2023

Xianglin Shi

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31 December 2023

Daniel C. Flynn

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31 December 2023

language of work or name

English

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publication date

15 June 2003

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6 May 2003

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full work available at URL

31 December 2023

published in

Journal of Cell Science

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volume

116

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issue

12

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page(s)

2585-2598

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on focus list of Wikimedia project

Wikimedia–NIOSH collaboration

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1 reference

2 February 2024

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

1 reference

24 May 2022

https://opencitations.net/index/coci/api/v1/citations/10.1016/0092-8674(91)90499-O

Intrinsic signals in the unique domain target p56(lck) to the plasma membrane independently of CD4.

1

1 reference

Requirement of pp60c-src expression for osteoclasts to form ruffled borders and resorb bone in mice

31 December 2023

2

1 reference

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

31 December 2023

4

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Phosphorylation of Raf-1 serine 338-serine 339 is an essential regulatory event for Ras-dependent activation and biological signaling

31 December 2023

5

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Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA

31 December 2023

6

1 reference

The SH3 domain directs acto-myosin-dependent targeting of v-Src to focal adhesions via phosphatidylinositol 3-kinase

31 December 2023

9

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Identification and sequence analysis of cDNAs encoding a 110-kilodalton actin filament-associated pp60src substrate

31 December 2023

10

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Complex formation of JAK2 with PP2A, P13K, and Yes in response to the hematopoietic cytokine interleukin-11

31 December 2023

12

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A third class of avian sarcoma viruses, defined by related transformation-specific proteins of Yamaguchi 73 and Esh sarcoma viruses.

31 December 2023

14

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Activation of the c-Src tyrosine kinase is required for the induction of mammary tumors in transgenic mice

31 December 2023

16

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Shp-2 mediates v-Src-induced morphological changes and activation of the anti-apoptotic protein kinase Akt.

31 December 2023

17

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Association of p60src with Triton X-100-resistant cellular structure correlates with morphological transformation

31 December 2023

19

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FRNK blocks v-Src-stimulated invasion and experimental metastases without effects on cell motility or growth

31 December 2023

21

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Chimeric constructs containing the SH4/Unique domains of cYes can restrict the ability of Src(527F) to upregulate heme oxygenase-1 expression efficiently

31 December 2023

22

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MEK kinase activity is not necessary for Raf-1 function

31 December 2023

23

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Impaired neurite outgrowth of src-minus cerebellar neurons on the cell adhesion molecule L1.

31 December 2023

24

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An essential role of phosphatidylinositol 3-kinase in myogenic differentiation.

31 December 2023

25

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S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes

31 December 2023

26

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c-Src enhances the spreading of src-/- fibroblasts on fibronectin by a kinase-independent mechanism

31 December 2023

27

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Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

31 December 2023

28

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Avian sarcoma virus Y73 genome sequence and structural similarity of its transforming gene product to that of Rous sarcoma virus

31 December 2023

29

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Activation of Src family kinases by hepatitis B virus HBx protein and coupled signaling to Ras

31 December 2023

30

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Association between the PDGF receptor and members of the src family of tyrosine kinases

31 December 2023

32

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Oncogenic Raf-1 disrupts epithelial tight junctions via downregulation of occludin

31 December 2023

34

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The SRC family protein tyrosine kinase p62yes controls polymeric IgA transcytosis in vivo

31 December 2023

35

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Identification of amino acid residues required for a specific interaction between Src-tyrosine kinase and proline-rich region of phosphatidylinositol-3' kinase

31 December 2023

36

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Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation

31 December 2023

37

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The coiled-coil domain of occludin can act to organize structural and functional elements of the epithelial tight junction

31 December 2023

38

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MEK mediates v-Src-induced disruption of the actin cytoskeleton via inactivation of the Rho-ROCK-LIM kinase pathway

31 December 2023

39

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Transformation by v-Src: Ras-MAPK and PI3K-mTOR mediate parallel pathways

31 December 2023

40

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Activation of phosphatidylinositol-3' kinase by Src-family kinase SH3 binding to the p85 subunit

31 December 2023

41

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Src can regulate carboxy terminal interactions with AFAP-110, which influence self-association, cell localization and actin filament integrity

31 December 2023

42

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Myristylation and palmitylation of Src family members: the fats of the matter

31 December 2023

44

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Transformation-specific tyrosine phosphorylation of a novel cellular protein in chicken cells expressing oncogenic variants of the avian cellular src gene

31 December 2023

45

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Phage display selection of ligand residues important for Src homology 3 domain binding specificity

31 December 2023

46

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Rho proteins, PI 3-kinases, and monocyte/macrophage motility

31 December 2023

47

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Myristoylation and differential palmitoylation of the HCK protein-tyrosine kinases govern their attachment to membranes and association with caveolae

31 December 2023

48

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Requirement for Src family protein tyrosine kinases in G2 for fibroblast cell division

31 December 2023

49

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Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

31 December 2023

50

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Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells

31 December 2023

51

1 reference

Angiotensin II Controls p21 Activity via pp60

31 December 2023

52

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Cysteine3 of Src family protein tyrosine kinase determines palmitoylation and localization in caveolae

31 December 2023

53

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Distinct ligand preferences of Src homology 3 domains from Src, Yes, Abl, Cortactin, p53bp2, PLCgamma, Crk, and Grb2.

31 December 2023

55

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Combined deficiencies of Src, Fyn, and Yes tyrosine kinases in mutant mice.

31 December 2023

56

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Cellular proteins homologous to the viral yes gene product

31 December 2023

57

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Distribution of c-yes-1 gene product in various cells and tissues

31 December 2023

58

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The SH3 and SH2 domains are capable of directing specificity in protein interactions between the non-receptor tyrosine kinases cSrc and cYes

31 December 2023

59

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Cellular functions regulated by Src family kinases

31 December 2023

61

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Specific proto-oncogenic tyrosine kinases of src family are enriched in cell-to-cell adherens junctions where the level of tyrosine phosphorylation is elevated

31 December 2023

62

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