Induction of metallothionein I by arsenic via metal-activated transcription factor 1. Critical role of c-terminal cysteine residues in arsenic sensing (Q23923855)

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journal article published in 2009

Language	Label	Description	Also known as
English	Induction of metallothionein I by arsenic via metal-activated transcription factor 1. Critical role of c-terminal cysteine residues in arsenic sensing	journal article published in 2009

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scholarly article

1 reference

15 October 2024

Induction of metallothionein I by arsenic via metal-activated transcription factor 1. Critical role of c-terminal cysteine residues in arsenic sensing (English)

1 reference

12 July 2017

NIOSH Health Effects Laboratory Division

object named as

HELD

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25 September 2023

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15 October 2024

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15 October 2024

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29 March 2020

1 reference

29 March 2020

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29 March 2020

2

object named as

Q. Ma

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author name string

X. He

1

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language of work or name

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publication date

8 May 2009

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Journal of Biological Chemistry

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284

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19

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12609-12621

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on focus list of Wikimedia project

Wikimedia–NIOSH collaboration

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Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2·Keap1·Cul3 complex and recruiting Nrf2·Maf to the antioxidant response element enhancer

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Superinduction of metallothionein I by inhibition of protein synthesis: role of a labile repressor in MTF-1 mediated gene transcription

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Induction of metallothionein l by phenolic antioxidants requires metal-activated transcription factor 1 (MTF-1) and zinc

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Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires the CNC (cap n collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2)

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Activation of gene expression by metal-responsive signal transduction pathways

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Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1.

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Cloning, chromosomal mapping and characterization of the human metal-regulatory transcription factor MTF-1

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A zinc-responsive factor interacts with a metal-regulated enhancer element (MRE) of the mouse metallothionein-I gene

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Metal-responsive transcription factor (MTF-1) and heavy metal stress response in Drosophila and mammalian cells: a functional comparison

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A novel cysteine cluster in human metal-responsive transcription factor 1 is required for heavy metal-induced transcriptional activation in vivo

2 references

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Heat and heavy metal stress synergize to mediate transcriptional hyperactivation by metal-responsive transcription factor MTF-1

2 references

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Regulation of metallothionein transcription by the metal-responsive transcription factor MTF-1: identification of signal transduction cascades that control metal-inducible transcription

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Regulation of metallothionein gene expression by oxidative stress and metal ions

2 references

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Cellular zinc sensors: MTF-1 regulation of gene expression

1 reference

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Inorganic arsenic: a need and an opportunity to improve risk assessment

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Copper homeostasis in Drosophila by complex interplay of import, storage and behavioral avoidance

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The zinc-sensing mechanism of mouse MTF-1 involves linker peptides between the zinc fingers.

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Blackfoot disease and arsenic: a never-ending story.

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Environmental cardiovascular disease

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Arsenic geochemistry and health

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Metal-responsive transcription factor (MTF-1) handles both extremes, copper load and copper starvation, by activating different genes

1 reference

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Predisposition to mouse thymic lymphomas in response to ionizing radiation depends on variant alleles encoding metal-responsive transcription factor-1 (Mtf-1).

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Differential induction of quinone reductase by phytoestrogens and protection against oestrogen-induced DNA damage

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Protection against zinc toxicity by metallothionein and zinc transporter 1

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Activity of metal-responsive transcription factor 1 by toxic heavy metals and H2O2 in vitro is modulated by metallothionein

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Putting its fingers on stressful situations: the heavy metal-regulatory transcription factor MTF-1.

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Metal response element (MRE)-binding transcription factor-1 (MTF-1): structure, function, and regulation

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The elusive function of metallothioneins

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Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium

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Regulation of metallothionein genes by heavy metals appears to be mediated by a zinc-sensitive inhibitor that interacts with a constitutively active transcription factor, MTF-1

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Functional domains of the heavy metal-responsive transcription regulator MTF-1.

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Carcinogenicity, teratogenicity and mutagenicity of arsenic.

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Identification of multiple metal regulatory elements in mouse metallothionein-I promoter by assaying synthetic sequences.

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Metal-responsive transcription factor-1 (MTF-1) is essential for embryonic liver development and heavy metal detoxification in the adult liver

1 reference

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Putative zinc-sensing zinc fingers of metal-response element-binding transcription factor-1 stabilize a metal-dependent chromatin complex on the endogenous metallothionein-I promoter.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M901204200

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Phosphorylation is involved in the activation of metal-regulatory transcription factor 1 in response to metal ions.

1 reference

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Developmental and reproductive toxicity of inorganic arsenic: animal studies and human concerns

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Conformational heterogeneity in the C-terminal zinc fingers of human MTF-1: an NMR and zinc-binding study

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12 December 2020

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10.1074/JBC.M901204200

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