Statins for the treatment of dementia (Q24236484)

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object named as

Bernadette McGuinness

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author name string

John O'Hare

2

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David Craig

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Roger Bullock

4

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Reem Malouf

5

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Peter Passmore

Cochrane Database of Systematic Reviews

6

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publication date

4 August 2010

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published in

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cites work

Statin therapy in Alzheimer's disease

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21 January 2018

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21 January 2018

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The Atorvastatin/Donepezil in Alzheimer's Disease Study (LEADe): design and baseline characteristics

21 January 2018

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Treatment with simvastatin in normocholesterolemic patients with Alzheimer's disease: A 26-week randomized, placebo-controlled, double-blind trial

21 January 2018

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Effects of statins on cognitive function in patients with Alzheimer's disease in galantamine clinical trials.

21 January 2018

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Neuropathological substrates of dementia and depression in vascular dementia, with a particular focus on cases with small infarct volumes.

21 January 2018

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https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein

21 January 2018

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https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Cerebral white matter lesions, vascular risk factors, and cognitive function in a population-based study: the Rotterdam Study.

21 January 2018

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Co-localization of cholesterol, apolipoprotein E and fibrillar Abeta in amyloid plaques

21 January 2018

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Bias in treatment assignment in controlled clinical trials.

21 January 2018

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https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

The Alzheimer's disease beta-secretase enzyme, BACE1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families

21 January 2018

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Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90,056 participants in 14 randomised trials of statins

21 January 2018

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Paraoxonase 1 activity: a new vascular marker of dementia?

21 January 2018

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Vascular factors in dementia: an overview

21 January 2018

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Cholesterol metabolism in the brain

21 January 2018

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Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts

21 January 2018

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Neuropathological assessment of the lesions of significance in vascular dementia

21 January 2018

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Prevalence of Alzheimer's disease in a community population of older persons. Higher than previously reported.

21 January 2018

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Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium

21 January 2018

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Simvastatin strongly reduces levels of Alzheimer's disease beta -amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo

21 January 2018

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Global prevalence of dementia: a Delphi consensus study

21 January 2018

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The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

21 January 2018

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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

21 January 2018

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Crossing the barrier: net flux of 27-hydroxycholesterol into the human brain.

21 January 2018

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Ischemic stress induces deposition of amyloid beta immunoreactivity in human brain

21 January 2018

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Statins and the risk of dementia

21 January 2018

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https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Cognitive impairment associated with atorvastatin and simvastatin

21 January 2018

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Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease

21 January 2018

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https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Lipid homeostasis and apolipoprotein E in the development and progression of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Simvastatin enhances learning and memory independent of amyloid load in mice.

21 January 2018

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https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Statin therapy is associated with reduced neuropathologic changes of Alzheimer disease

21 January 2018

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https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Isoprenoids as mediators of the biological effects of statins

21 January 2018

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https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Lipid lowering agents are associated with a slower cognitive decline in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Statins for the prevention of dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Apolipoprotein E4 induces neuronal cell death under conditions of suppressed de novo cholesterol synthesis.

21 January 2018

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https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

High-density lipoprotein cholesterol in differential diagnosis of senile dementia.

21 January 2018

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https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Serum cholesterol and intellectual performance.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Effects of lovastatin on cognitive function and psychological well-being

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Characterization of stable complexes involving apolipoprotein E and the amyloid beta peptide in Alzheimer's disease brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Serum total cholesterol, apolipoprotein E epsilon 4 allele, and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Smoking and risk of dementia and Alzheimer's disease in a population-based cohort study: the Rotterdam Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Enhanced oxidizability of ubiquinol and alpha-tocopherol during lovastatin treatment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Serum paraoxonase activity changes in patients with Alzheimer's disease and vascular dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

The relationship of hypertension in the elderly to AD, vascular dementia, and cognitive function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Cholesterol in neurologic disorders of the elderly: stroke and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Relation of plasma lipids to Alzheimer disease and vascular dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Effect of vascular lesions on cognition in Alzheimer's disease: a community-based study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Use of lipid-lowering agents, indication bias, and the risk of dementia in community-dwelling elderly people.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Plasma antioxidant activity and vascular dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Cholesterol and Alzheimer's disease: is there a link?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Brain infarction and the clinical expression of Alzheimer disease. The Nun Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Cortical senile plaques in coronary artery disease, aging and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Circulating cholesterol levels, apolipoprotein E genotype and dementia severity influence the benefit of atorvastatin treatment in Alzheimer's disease: results of the Alzheimer's Disease Cholesterol-Lowering Treatment (ADCLT) trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Type 2 diabetes mellitus, cognitive impairment and dementia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Alzheimer's disease beyond APOE.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Association between high-density lipoprotein and cognitive impairment in the oldest old.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Amyloidogenic processing of beta-amyloid precursor protein in intracellular compartments

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Aging and the occurrence of dementia: findings from a population-based cohort with a large sample of nonagenarians

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Statin-associated memory loss: analysis of 60 case reports and review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Subchronic toxicity of atorvastatin, a hydroxymethylglutaryl-coenzyme A reductase inhibitor, in beagle dogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

HMG-CoA reductase inhibitors improve endothelial dysfunction in normocholesterolemic hypertension via reduced production of reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Is Alzheimer's disease an apolipoprotein E amyloidosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

A fluid connection: cholesterol and Abeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Brain region-dependent increases in beta-amyloid and apolipoprotein E levels in hypercholesterolemic rabbits

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Incidence and risk factors of vascular dementia and Alzheimer's disease in a defined elderly Japanese population: the Hisayama Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Prevention and treatment of dementia or Alzheimer's disease by statins: a meta-analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Lipoprotein profile in older patients with vascular dementia and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Cholesterol-dependent Generation of a Seeding Amyloid β-Protein in Cell Culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

Low-Density Lipoprotein Cholesterol and the Risk of Dementia With Stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

7 January 2021

New possible role of statins in age-related diseases

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

7 January 2021

High-dose atorvastatin after stroke or transient ischemic attack

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

7 January 2021

Serum cholesterol concentrations are associated with visuomotor speed in men: findings from the third National Health and Nutrition Examination Survey, 1988-1994.

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

7 January 2021

Alzheimer's disease: genes, proteins, and therapy

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

7 January 2021

Associations of lipoprotein cholesterols, apolipoproteins A-I and B, and triglycerides with carotid atherosclerosis and coronary heart disease. The Atherosclerosis Risk in Communities (ARIC) Study.

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

7 January 2021

Interactions of apolipoprotein E genotype, total cholesterol level, age, and sex in prediction of Alzheimer's disease: a case-control study

1 reference

https://api.crossref.org/works/10.1002%2F14651858.CD007514.PUB2

7 January 2021