Cloning, expression and chromosomal localization of a novel human dipeptidyl peptidase (DPP) IV homolog, DPP8 (Q24290340)

dipeptidyl-peptidase activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

C A Abbott

1

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D M Yu

2

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E Woollatt

3

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G R Sutherland

4

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G W McCaughan

5

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M D Gorrell

Identification of the bile canalicular cell surface molecule GP110 as the ectopeptidase dipeptidyl peptidase IV: an analysis by tissue distribution, purification and N-terminal amino acid sequence

6

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language of work or name

English

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publication date

October 2000

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published in

FEBS Journal

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volume

267

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issue

20

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page(s)

6140-50

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cites work

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Dipeptidyl peptidase IV (DPIV/CD26) degradation of glucagon. Characterization of glucagon degradation products and DPIV-resistant analogs

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Functional role of CD26 on human B lymphocytes

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Inhibition of dipeptidyl aminopeptidase IV (DP-IV) by Xaa-boroPro dipeptides and use of these inhibitors to examine the role of DP-IV in T-cell function

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Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers

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Mouse fibroblast activation protein: molecular cloning, alternative splicing and expression in the reactive stroma of epithelial cancers

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Non-conservation of a catalytic residue in a dipeptidyl aminopeptidase IV-related protein encoded by a gene on human chromosome 7

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Identification of the 170-kDa melanoma membrane-bound gelatinase (seprase) as a serine integral membrane protease

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Mouse fibroblast-activation protein--conserved Fap gene organization and biochemical function as a serine protease

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Fibroblast activation protein, a dual specificity serine protease expressed in reactive human tumor stromal fibroblasts

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A novel protease-docking function of integrin at invadopodia

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Dipeptidyl-peptidase IV-beta--further characterization and comparison to dipeptidyl-peptidase IV activity of CD26.

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Attractin (DPPT-L), a member of the CUB family of cell adhesion and guidance proteins, is secreted by activated human T lymphocytes and modulates immune cell interactions

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The kelch repeat superfamily of proteins: propellers of cell function

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Sequence, purification, and cloning of an intracellular serine protease, quiescent cell proline dipeptidase

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Isolation and expression of novel human glutamate carboxypeptidases with N-acetylated alpha-linked acidic dipeptidase and dipeptidyl peptidase IV activity

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A role for dipeptidyl peptidase IV in suppressing the malignant phenotype of melanocytic cells

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Isolation and characterization of dipeptidyl aminopeptidase IV from human kidney cortex

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Inhibitors of dipeptidyl peptidase IV/CD26 suppress activation of human MBP-specific CD4+ T cell clones.

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Triggering of the proteinase dipeptidyl peptidase IV (CD26) amplifies human T lymphocyte proliferation.

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The purification, characterization and analysis of primary and secondary-structure of prolyl oligopeptidase from human lymphocytes. Evidence that the enzyme belongs to the alpha/beta hydrolase fold family.

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Structure and localization of the mouse prolyl oligopeptidase gene.

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The gene for fibroblast activation protein alpha (FAP), a putative cell surface-bound serine protease expressed in cancer stroma and wound healing, maps to chromosome band 2q23

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Linkage mapping in 29 Bardet-Biedl syndrome families confirms loci in chromosomal regions 11q13, 15q22.3-q23, and 16q21.

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The mouse mahogany locus encodes a transmembrane form of human attractin

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The evolution of proteinase substrates with special reference to dipeptidylpeptidase IV.

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Identification of an alternatively spliced seprase mRNA that encodes a novel intracellular isoform

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Rump white inversion in the mouse disrupts dipeptidyl aminopeptidase-like protein 6 and causes dysregulation of Kit expression

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Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes

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The role of dipeptidyl peptidase IV in human T lymphocyte activation. Inhibitors and antibodies against dipeptidyl peptidase IV suppress lymphocyte proliferation and immunoglobulin synthesis in vitro

21 January 2018

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Fibroblast activation protein: A cell surface dipeptidyl peptidase and gelatinase expressed by stellate cells at the tissue remodelling interface in human cirrhosis

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Early phosphorylation events induced by DPIV/CD26-specific inhibitors

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Comparison of dipeptidyl peptidase IV prepared from pig liver and kidney

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Expression of the rat CD26 antigen (dipeptidyl peptidase IV) on subpopulations of rat lymphocytes

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Characterization of dipeptidyl peptidase IV (CD26) from human lymphocytes

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Intragraft cytokine mRNA levels in human liver allograft rejection analysed by reverse transcription and semiquantitative polymerase chain reaction amplification

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Two highly conserved glutamic acid residues in the predicted β propeller domain of dipeptidyl peptidase IV are required for its enzyme activity

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Suppression of arthritis by the inhibitors of dipeptidyl peptidase IV

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Regulation of the biological activity of glucagon-like peptide 2 in vivo by dipeptidyl peptidase IV

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Inhibitors of dipeptidyl peptidase IV induce secretion of transforming growth factor-beta 1 in PWM-stimulated PBMC and T cells

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Binding to human dipeptidyl peptidase IV by adenosine deaminase and antibodies that inhibit ligand binding involves overlapping, discontinuous sites on a predicted β propeller domain

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Dipeptidyl peptidase IV from human serum: purification, characterization, and N-terminal amino acid sequence

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Inhibition of CD26/dipeptidyl peptidase IV activity in vivo prolongs cardiac allograft survival in rat recipients

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Dipeptidyl peptidase IV is down-regulated in rat hepatoma cells at the mRNA level

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Subregional mapping of the human lymphocyte prolyl oligopeptidase gene (PREP) to human chromosome 6q22

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Oligopeptidases, and the emergence of the prolyl oligopeptidase family.

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