Structure-guided identification of C3d residues essential for its binding to complement receptor 2 (CD21) (Q24290411)

GOA release 2020-03-11

complement binding

1 reference

Evidence for multiple sites of interaction in C3 for complement receptor type 2 (C3d/EBV receptor, CD21)

GOA release 2020-03-11

author name string

L Clemenza

series ordinal

1

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D E Isenman

series ordinal

2

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language of work or name

English

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publication date

1 October 2000

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published in

Journal of Immunology

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volume

165

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issue

7

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page(s)

3839-48

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cites work

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7 January 2021

Solution structure of a pair of complement modules by nuclear magnetic resonance

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Site-directed mutagenesis by overlap extension using the polymerase chain reaction

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Abnormal B lymphocyte development, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule.

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7 January 2021

Functional properties of complement factor H-related proteins FHR-3 and FHR-4: binding to the C3d region of C3b and differential regulation by heparin

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7 January 2021

The regulators of complement activation (RCA) gene cluster

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Disruption of the Cr2 locus results in a reduction in B-1a cells and in an impaired B cell response to T-dependent antigen.

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7 January 2021

Impairment of T-cell-dependent B-cell responses and B-1 cell development in CD19-deficient mice.

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7 January 2021

Enhanced molecular mimicry of CEA using photoaffinity crosslinked C3d peptide

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The unactivated form of the first component of human complement, C1

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7 January 2021

Mapping of the C3d receptor (CR2)-binding site and a neoantigenic site in the C3d domain of the third component of complement

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7 January 2021

Expression of a synthetic bovine rhodopsin gene in monkey kidney cells

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7 January 2021

Structure-function analysis of the active sites of complement receptor type 1

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Identification of residues within the 727-767 segment of human complement component C3 important for its interaction with factor H and with complement receptor 1 (CR1, CD35).

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Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution

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7 January 2021

Mapping of the Epstein-Barr virus and C3dg binding sites to a common domain on complement receptor type 2.

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7 January 2021

In vivo inhibition of the antibody response by a complement receptor-specific monoclonal antibody.

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Intersection of the complement and immune systems: a signal transduction complex of the B lymphocyte-containing complement receptor type 2 and CD19

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7 January 2021

Antibody response to a T-dependent antigen requires B cell expression of complement receptors

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CD19: lowering the threshold for antigen receptor stimulation of B lymphocytes

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7 January 2021

Suppression of the Immune Response by a Soluble Complement Receptor of B Lymphocytes

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C3d of complement as a molecular adjuvant: bridging innate and acquired immunity

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X-ray crystal structure of C3d: a C3 fragment and ligand for complement receptor 2

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7 January 2021

The role of complement and complement receptors in induction and regulation of immunity.

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The CD19/CR2/TAPA-1 complex of B lymphocytes: linking natural to acquired immunity

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7 January 2021