A new family of Cdc42 effector proteins, CEPs, function in fibroblast and epithelial cell shape changes (Q24290414)

Cell division cycle 42

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CDC42 effector protein 5

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CDC42 effector protein 4

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CDC42 effector protein 2

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CDC42 effector protein 1

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signal transduction

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CDC42 effector protein (Rho GTPase binding) 5

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Cell division cycle 42

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Journal of Biological Chemistry

author name string

D S Hirsch

series ordinal

1

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D M Pirone

series ordinal

2

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P D Burbelo

series ordinal

3

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language of work or name

English

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publication date

12 January 2001

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published in

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volume

276

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issue

2

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page(s)

875-83

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https://api.crossref.org/works/10.1074%2FJBC.M007039200

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

A requirement for Rho and Cdc42 during cytokinesis in Xenopus embryos.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

A role for Rho-like GTPases in the polarisation of mouse eight-cell blastomeres.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Cdc42 controls secretory and endocytic transport to the basolateral plasma membrane of MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Cdc42 and Rac1 induce integrin-mediated cell motility and invasiveness through PI(3)K.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Rho GTPases control polarity, protrusion, and adhesion during cell movement

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Requirements for both Rac1 and Cdc42 in membrane ruffling and phagocytosis in leukocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

A role for Cdc42 in macrophage chemotaxis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Rho GTPases and their effector proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

The essential role of profilin in the assembly of actin for microspike formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

PAK4, a novel effector for Cdc42Hs, is implicated in the reorganization of the actin cytoskeleton and in the formation of filopodia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

p21-activated kinase 1 (Pak1) regulates cell motility in mammalian fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

A role for p21-activated kinase in endothelial cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

PAK promotes morphological changes by acting upstream of Rac.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

MSE55, a Cdc42 effector protein, induces long cellular extensions in fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

SPECs, small binding proteins for Cdc42

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Intracellular localization of the P21rho proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

The Borgs, a new family of Cdc42 and TC10 GTPase-interacting proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Use of double-stranded RNA interference in Drosophila cell lines to dissect signal transduction pathways.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Structure of the small G protein Cdc42 bound to the GTPase-binding domain of ACK

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

PSM, an insulin-dependent, pro-rich, PH, SH2 domain containing partner of the insulin receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Involvement of Cdc42 small G protein in cell-cell adhesion, migration and morphology of MDCK cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Directed actin polymerization is the driving force for epithelial cell-cell adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Essential functions of ezrin in maintenance of cell shape and lamellipodial extension in normal and transformed fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

AP-1-mediated invasion requires increased expression of the hyaluronan receptor CD44.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Krp1, a novel kelch related protein that is involved in pseudopod elongation in transformed cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Distinct cellular effects and interactions of the Rho-family GTPase TC10.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Characterization of TCL, a new GTPase of the rho family related to TC10 andCcdc42

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

The Small GTPases Rho and Rac Are Required for the Establishment of Cadherin-dependent Cell–Cell Contacts

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Effects of regulated expression of mutant RhoA and Rac1 small GTPases on the development of epithelial (MDCK) cell polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200

Inducible recruitment of Cdc42 or WASP to a cell-surface receptor triggers actin polymerization and filopodium formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M007039200