IRSp53 is an essential intermediate between Rac and WAVE in the regulation of membrane ruffling (Q24290667)

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H Yamaguchi

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S Suetsugu

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T Takenawa

N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases

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language of work or name

English

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publication date

7 December 2000

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published in

Nature

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volume

408

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issue

6813

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page(s)

732-5

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cites work

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7 January 2021

Induction of filopodium formation by a WASP-related actin-depolymerizing protein N-WASP

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7 January 2021

Phosphatidylinositol 4,5-bisphosphate induces actin-based movement of raft-enriched vesicles through WASP-Arp2/3.

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7 January 2021

Neural Wiskott-Aldrich syndrome protein is implicated in the actin-based motility of Shigella flexneri

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7 January 2021

Activation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nucleation by Arp2/3 complex and bacterial actin-based motility

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7 January 2021

Actin-based motility of vaccinia virus mimics receptor tyrosine kinase signalling.

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7 January 2021

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

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7 January 2021

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7 January 2021

The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly

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7 January 2021

WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac

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7 January 2021

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

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7 January 2021

Characterization and cloning of a 58/53-kDa substrate of the insulin receptor tyrosine kinase

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7 January 2021

Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex

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7 January 2021

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7 January 2021

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7 January 2021

A conserved binding motif defines numerous candidate target proteins for both Cdc42 and Rac GTPases

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7 January 2021

The Wiskott-Aldrich syndrome protein directs actin-based motility by stimulating actin nucleation with the Arp2/3 complex

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7 January 2021

The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments

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7 January 2021

Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins.

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7 January 2021

The Arp2/3 complex branches filament barbed ends: functional antagonism with capping proteins

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7 January 2021

Relationship between Arp2/3 complex and the barbed ends of actin filaments at the leading edge of carcinoma cells after epidermal growth factor stimulation

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7 January 2021

Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia

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7 January 2021

Phosphorylation of WAVE downstream of mitogen-activated protein kinase signaling

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7 January 2021