Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation (Q24290777)

GOA release 2020-03-11

P Kavsak

1

P

Kavsak

1 reference

31 January 2024

R K Rasmussen

2

R K

Rasmussen

1 reference

31 January 2024

C G Causing

3

C G

Causing

1 reference

31 January 2024

S Bonni

4

S

Bonni

1 reference

31 January 2024

H Zhu

5

H

Zhu

1 reference

31 January 2024

G H Thomsen

6

G H

Thomsen

1 reference

31 January 2024

J L Wrana

7

J L

Induction of inhibitory Smad6 and Smad7 mRNA by TGF-beta family members

Wrana

1 reference

31 January 2024

language of work or name

English

0 references

publication date

December 2000

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published in

Molecular Cell

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volume

6

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issue

6

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page(s)

1365-75

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cites work

1 reference

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7 January 2021

Differential requirement for type I and type II transforming growth factor beta receptor kinase activity in ligand-mediated receptor endocytosis

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7 January 2021

Ubiquitin and the control of protein fate in the secretory and endocytic pathways

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7 January 2021

SUMO-1 modification of Mdm2 prevents its self-ubiquitination and increases Mdm2 ability to ubiquitinate p53.

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7 January 2021

Rapid flux in transforming growth factor-beta receptors on bone cells

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7 January 2021

The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules

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7 January 2021

Smads: transcriptional activators of TGF-beta responses

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7 January 2021

Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor

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7 January 2021

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7 January 2021

NPl1, an essential yeast gene involved in induced degradation of Gap1 and Fur4 permeases, encodes the Rsp5 ubiquitin-protein ligase.

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7 January 2021

The types II and III transforming growth factor-beta receptors form homo-oligomers

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7 January 2021

https://api.crossref.org/works/10.1016%2FS1097-2765%2800%2900134-9

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7 January 2021

Gettin' down with ubiquitin: turning off cell-surface receptors, transporters and channels

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7 January 2021

Smad6 inhibits signalling by the TGF-beta superfamily.

1 reference

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7 January 2021

Transforming growth factor beta1 induces nuclear export of inhibitory Smad7

1 reference

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7 January 2021

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

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7 January 2021

Processing of the transforming growth factor beta type I and II receptors. Biosynthesis and ligand-induced regulation

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7 January 2021

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

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7 January 2021

Ubiquitin-dependent degradation of TGF-beta-activated smad2.

1 reference

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7 January 2021

MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

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7 January 2021

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling

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7 January 2021

Nitrogen-regulated ubiquitination of the Gap1 permease of Saccharomyces cerevisiae

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7 January 2021

Regulation of stability and function of the epithelial Na+ channel (ENaC) by ubiquitination

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7 January 2021

Negative feedback regulation of TGF-beta signaling by the SnoN oncoprotein

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7 January 2021

SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor beta signaling

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7 January 2021

SARA, a FYVE domain protein that recruits Smad2 to the TGFbeta receptor

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7 January 2021

Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway.

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7 January 2021

Endocytosis and degradation of the growth hormone receptor are proteasome-dependent

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7 January 2021

Biosynthesis of the type I and type II TGF-beta receptors. Implications for complex formation

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7 January 2021

Regulation of Smad activity

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7 January 2021

Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7

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7 January 2021

A SMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation

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7 January 2021

Down-regulation of transforming growth factor-beta receptors: cooperativity between the types I, II, and III receptors and modulation at the cell surface

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7 January 2021