Polycystin-2, the protein mutated in autosomal dominant polycystic kidney disease (ADPKD), is a Ca2+-permeable nonselective cation channel (Q24290926)

sodium ion transmembrane transport

GOA release 2020-03-11

1 reference

autosomal dominant polycystic kidney

GOA release 2020-03-11

1 reference

S González-Perrett

1

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K Kim

2

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C Ibarra

3

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A E Damiano

4

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E Zotta

5

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M Batelli

6

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P C Harris

7

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I L Reisin

8

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M A Arnaout

9

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H F Cantiello

Proceedings of the National Academy of Sciences of the United States of America

10

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language of work or name

English

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publication date

30 January 2001

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published in

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volume

98

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issue

3

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page(s)

1182-7

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cites work

Cellular and subcellular distribution of polycystin-2, the protein product of the PKD2 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14729

Polycystin-L is a calcium-regulated cation channel permeable to calcium ions

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14729

Identification of PKDL, a novel polycystic kidney disease 2-like gene whose murine homologue is deleted in mice with kidney and retinal defects

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14729

Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14729

PKD1 interacts with PKD2 through a probable coiled-coil domain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14729

PKD2, a gene for polycystic kidney disease that encodes an integral membrane protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14729

Epithelial sodium channel related to proteins involved in neurodegeneration

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14729

Bilateral polycystic disease of the kidneys; a follow-up of two hundred and eighty-four patients and their families

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14729

Molecular genetics and pathogenesis of autosomal dominant polycystic kidney disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14729

Identification and characterization of polycystin-2, the PKD2 gene product

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14729

Coordinate expression of the autosomal dominant polycystic kidney disease proteins, polycystin-2 and polycystin-1, in normal and cystic tissue.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14729

Properties of single Drosophila Trpl channels expressed in Sf9 insect cells

27 September 2017

1 reference

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Endogenous chloride channels of insect sf9 cells. Evidence for coordinated activity of small elementary channel units.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14729

In vitro function of cyst epithelium from human polycystic kidney

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14729

Expression of Drosophila melanogaster P-glycoproteins is associated with ATP channel activity

27 September 2017

1 reference

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Placental transfer of inorganic ions and water

27 September 2017

1 reference

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The polycystic kidney disease 1 gene encodes a 14 kb transcript and lies within a duplicated region on chromosome 16. The European Polycystic Kidney Disease Consortium

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=14729

Mating, channels and kidney cysts

29 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.98.3.1182

Actin filaments regulate epithelial Na+ channel activity

21 January 2018

1 reference

12 December 2020

Properties of two multisubstate Cl- channels from human syncytiotrophoblast reconstituted on planar lipid bilayers

1 reference

12 December 2020

Amiloride-sensitive sodium uptake into human placental brush border membrane vesicles

1 reference

12 December 2020

Epithelial transport in polycystic kidney disease

1 reference

12 December 2020

Amiloride-sensitive cation channel in apical membrane of inner medullary collecting duct

1 reference

12 December 2020

Polycystic kidney disease: The complete structure of the PKD1 gene and its protein

1 reference

12 December 2020

A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.98.3.1182

7 January 2021