Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks (Q24291688)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11555662%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

title

Granzyme A activates an endoplasmic reticulum-associated caspase-independent nuclease to induce single-stranded DNA nicks (English)

1 reference

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Acidic nuclear phosphoprotein 32 family member A

11 November 2019

main subject

endoplasmic reticulum

0 references

1 reference

NME/NM23 nucleoside diphosphate kinase 1

GOA release 2020-03-11

1 reference

SET nuclear proto-oncogene

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Eric L Greer

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11555662%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

author name string

Beresford PJ

1

1 reference

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11 November 2019

Zhang D

2

1 reference

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11 November 2019

Oh DY

3

1 reference

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11 November 2019

Fan Z

4

1 reference

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11 November 2019

Russo ML

6

1 reference

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11 November 2019

Jaju M

7

1 reference

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11 November 2019

Lieberman J

8

1 reference

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11 November 2019

language of work or name

English

0 references

publication date

12 September 2001

1 reference

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11 November 2019

number of pages

9

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

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11 November 2019

volume

276

1 reference

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11 November 2019

issue

46

1 reference

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11 November 2019

page(s)

43285-43293

1 reference

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Lymphocyte-mediated cytotoxicity: two pathways and multiple effector molecules

11 November 2019

cites work

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A natural killer cell granule protein that induces DNA fragmentation and apoptosis

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Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

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Activation of an interleukin 1 converting enzyme-dependent apoptosis pathway by granzyme B.

21 January 2018

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Proteolytic activation of the cell death protease Yama/CPP32 by granzyme B.

21 January 2018

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DFF45/ICAD can be directly processed by granzyme B during the induction of apoptosis

21 January 2018

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Granzyme A initiates an alternative pathway for granule-mediated apoptosis.

21 January 2018

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Granzymes A and B directly cleave lamins and disrupt the nuclear lamina during granule-mediated cytolysis

21 January 2018

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Recombinant human granzyme A binds to two putative HLA-associated proteins and cleaves one of them

21 January 2018

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Induction of rapid histone degradation by the cytotoxic T lymphocyte protease Granzyme A.

21 January 2018

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Can, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set gene

21 January 2018

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Purification and characterization of two putative HLA class II associated proteins: PHAPI and PHAPII

21 January 2018

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Cellular localization and expression of template-activating factor I in different cell types.

21 January 2018

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Functional interaction between nucleosome assembly proteins and p300/CREB-binding protein family coactivators

21 January 2018

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Regulation of histone acetylation and transcription by INHAT, a human cellular complex containing the set oncoprotein

21 January 2018

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The myeloid leukemia-associated protein SET is a potent inhibitor of protein phosphatase 2A

21 January 2018

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Regulation of protein phosphatase 2A activity by caspase-3 during apoptosis

21 January 2018

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Molecular identification of I1PP2A, a novel potent heat-stable inhibitor protein of protein phosphatase 2A.

21 January 2018

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Structure of pp32, an acidic nuclear protein which inhibits oncogene-induced formation of transformed foci

21 January 2018

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CRM1 is responsible for intracellular transport mediated by the nuclear export signal

21 January 2018

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CRM1 is an export receptor for leucine-rich nuclear export signals

21 January 2018

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Protein ligands to HuR modulate its interaction with target mRNAs in vivo

21 January 2018

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Expression and purification of enzymatically active recombinant granzyme B in a baculovirus system

21 January 2018

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Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions

21 January 2018

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Continuous cultures of fused cells secreting antibody of predefined specificity

21 January 2018

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Nuclease detection in SDS-polyacrylamide gel electrophoresis

21 January 2018

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Participation of core histone "tails" in the stabilization of the chromatin solenoid

21 January 2018

1 reference

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A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

21 January 2018

1 reference

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Synergistic roles of granzymes A and B in mediating target cell death by rat basophilic leukemia mast cell tumors also expressing cytolysin/perforin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M108137200

Granzyme A is an interleukin 1 beta-converting enzyme

21 January 2018

1 reference

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Granzyme A released upon stimulation of cytotoxic T lymphocytes activates the thrombin receptor on neuronal cells and astrocytes

21 January 2018

1 reference

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Importance of the P4' residue in human granzyme B inhibitors and substrates revealed by scanning mutagenesis of the proteinase inhibitor 9 reactive center loop

21 January 2018

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Perforin-dependent nuclear targeting of granzymes: A central role in the nuclear events of granule-exocytosis-mediated apoptosis?

21 January 2018

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HRX leukemic fusion proteins form a heterocomplex with the leukemia-associated protein SET and protein phosphatase 2A

21 January 2018

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Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation.

21 January 2018

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7 January 2021

Functional domains of template-activating factor-I as a protein phosphatase 2A inhibitor

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7 January 2021

Histone- and chromatin-binding activity of template activating factor-I

1 reference

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7 January 2021

Granzyme A loading induces rapid cytolysis and a novel form of DNA damage independently of caspase activation

1 reference

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7 January 2021

Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases

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7 January 2021

NAP-I is a functional homologue of TAF-I that is required for replication and transcription of the adenovirus genome in a chromatin-like structure

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7 January 2021

Stimulation of DNA transcription by the replication factor from the adenovirus genome in a chromatin-like structure

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7 January 2021

Template activating factor-I remodels the chromatin structure and stimulates transcription from the chromatin template

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7 January 2021

Identifiers

DOI

10.1074/JBC.M108137200

2 references

Consolidated OpenCitations Corpus – April 2017

2733672

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11555662%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

2733672

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

2733672