CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration (Q24291780)

cell motility

1 reference

Engulfment and cell motility 1

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Cell death abnormality protein 12;ELMO domain-containing protein CELE_Y106G6E.5

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Uncharacterized protein CELE_C02F4.1

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1 reference

T L Gumienny

1

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E Brugnera

2

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A C Tosello-Trampont

3

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J M Kinchen

4

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L B Haney

5

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K Nishiwaki

6

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S F Walk

7

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M E Nemergut

8

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I G Macara

9

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R Francis

10

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T Schedl

11

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Y Qin

12

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L Van Aelst

13

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M O Hengartner

14

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K S Ravichandran

alphavbeta5 integrin recruits the CrkII-Dock180-rac1 complex for phagocytosis of apoptotic cells

15

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language of work or name

English

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publication date

5 October 2001

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published in

Cell

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volume

107

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page(s)

27-41

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issue

1

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cites work

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7 January 2021

A cell that dies during wild-type C. elegans development can function as a neuron in a ced-3 mutant

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Rho GTPases and their effector proteins

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Identification of two distinct mechanisms of phagocytosis controlled by different Rho GTPases

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Regulation of cell contraction and membrane ruffling by distinct signals in migratory cells

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Function of Rho family proteins in actin dynamics during phagocytosis and engulfment

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7 January 2021

A common set of engulfment genes mediates removal of both apoptotic and necrotic cell corpses in C. elegans

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7 January 2021

Drosophila myoblast city encodes a conserved protein that is essential for myoblast fusion, dorsal closure, and cytoskeletal organization

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7 January 2021

DOCK180, a major CRK-binding protein, alters cell morphology upon translocation to the cell membrane

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7 January 2021

Mutations affecting programmed cell deaths in the nematode Caenorhabditis elegans.

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Apoptosis: corralling the corpses

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C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

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7 January 2021

Mechanisms of mRNA surveillance in eukaryotes

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The Caenorhabditis elegans gonad: a test tube for cell and developmental biology

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Role of Crk oncogene product in physiologic signaling.

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Activation of Rac1 by a Crk SH3-binding protein, DOCK180

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Evidence that DOCK180 up-regulates signals from the CrkII-p130(Cas) complex

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7 January 2021

Development of the male reproductive system and sexual transformation in the nematode Caenorhabditis elegans

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7 January 2021

CAS/Crk coupling serves as a "molecular switch" for induction of cell migration

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Requirement for Rho GTPases and PI 3-kinases during apoptotic cell phagocytosis by macrophages

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Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans.

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7 January 2021

The ATP binding cassette transporter ABC1, is required for the engulfment of corpses generated by apoptotic cell death.

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7 January 2021

Fc receptor-mediated phagocytosis requires CDC42 and Rac1.

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A novel viral oncogene with structural similarity to phospholipase C

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7 January 2021

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Chromatin docking and exchange activity enhancement of RCC1 by histones H2A and H2B

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7 January 2021

Non-adherent cell-specific expression of DOCK2, a member of the human CDM-family proteins

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7 January 2021

Rho GTPases control polarity, protrusion, and adhesion during cell movement

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7 January 2021

Myoblast city, the Drosophila homolog of DOCK180/CED-5, is required in a Rac signaling pathway utilized for multiple developmental processes

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7 January 2021

CED-2/CrkII and CED-10/Rac control phagocytosis and cell migration in Caenorhabditis elegans

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7 January 2021

The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

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7 January 2021

Corpse clearance defines the meaning of cell death

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7 January 2021

Temporal and spatial expression patterns of the small heat shock (hsp16) genes in transgenic Caenorhabditis elegans

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7 January 2021

Post-embryonic cell lineages of the nematode, Caenorhabditis elegans

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7 January 2021

Differential inhibition of signaling pathways by dominant-negative SH2/SH3 adapter proteins

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7 January 2021

Rho GTPases and signaling networks

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7 January 2021

The C. elegans cell corpse engulfment gene ced-7 encodes a protein similar to ABC transporters.

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7 January 2021

Regulated nuclear import of Rel proteins in the Drosophila immune response.

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7 January 2021

CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans.

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7 January 2021