The Pin2/TRF1-interacting protein PinX1 is a potent telomerase inhibitor (Q24291889)

PIN2 (TERF1) interacting telomerase inhibitor 1

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negative regulation of telomerase activity

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PIN2/TERF1 interacting, telomerase inhibitor 1

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G-patch: a new conserved domain in eukaryotic RNA-processing proteins and type D retroviral polyproteins

author name string

X Z Zhou

series ordinal

1

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K P Lu

series ordinal

2

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language of work or name

English

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publication date

2 November 2001

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published in

Cell

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volume

107

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issue

3

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page(s)

347-59

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cites work

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

A critical role for telomeres in suppressing and facilitating carcinogenesis

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

TRF1 is a dimer and bends telomeric DNA

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Association of 8p23 Deletions with Poor Survival in Head and Neck Cancer

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Extension of life-span by introduction of telomerase into normal human cells

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Telomerase activity in normal and malignant hematopoietic cells

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Telomere elongation in immortal human cells without detectable telomerase activity

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

A human telomeric protein

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

RAP1 protein interacts with yeast telomeres in vivo: overproduction alters telomere structure and decreases chromosome stability

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Variability at the telomeres of the human X/Y pseudoautosomal region

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Regulation of telomere length and function by a Myb-domain protein in fission yeast

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

The catalytic subunit of yeast telomerase

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

A physical map of 30,000 human genes

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Est1 and Cdc13 as comediators of telomerase access

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

The RNA component of human telomerase

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

SV40-INDUCED TRANSFORMATION OF HUMAN DIPLOID CELLS: CRISIS AND RECOVERY

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Identification of a specific telomere terminal transferase activity in Tetrahymena extracts

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Creation of human tumour cells with defined genetic elements

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Inhibition of telomerase limits the growth of human cancer cells.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Telomerase activity is sufficient to allow transformed cells to escape from crisis

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Telomeres shorten during ageing of human fibroblasts

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Telomere reduction in human colorectal carcinoma and with ageing

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

The serial cultivation of human diploid cell strains

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Frequent allelic loss and homozygous deletion in chromosome band 8p23 in oral cancer.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Specific association of human telomerase activity with immortal cells and cancer

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Repression of the gene encoding the TGF-beta type II receptor is a major target of the EWS-FLI1 oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Telomeric protein Pin2/TRF1 induces mitotic entry and apoptosis in cells with short telomeres and is down-regulated in human breast tumors

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Telomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaks

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Telomerase activation by the E6 gene product of human papillomavirus type 16.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Essential role of mouse telomerase in highly proliferative organs

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Identification of the gene for a novel liver-related putative tumor suppressor at a high-frequency loss of heterozygosity region of chromosome 8p23 in human hepatocellular carcinoma

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Reverse transcriptase motifs in the catalytic subunit of telomerase

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Evidence for a NIMA-like mitotic pathway in vertebrate cells

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

A human peptidyl-prolyl isomerase essential for regulation of mitosis

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

The prolyl isomerase Pin1 restores the function of Alzheimer-associated phosphorylated tau protein

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Function of WW domains as phosphoserine- or phosphothreonine-binding modules

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Involvement of the silencer and UAS binding protein RAP1 in regulation of telomere length

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Telomeres and their control

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

High density deletion mapping of bladder cancer localizes the putative tumor suppressor gene between loci D8S504 and D8S264 at chromosome 8p23.3.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Telomerase catalytic subunit homologs from fission yeast and human

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

A specific interaction between the telomeric protein Pin2/TRF1 and the mitotic spindle.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Association of nucleoside diphosphate kinase nm23-H2 with human telomeres

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Repression of an alternative mechanism for lengthening of telomeres in somatic cell hybrids

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Telomeres and telomerase: implications for cancer and aging

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Characterization and cell cycle regulation of the related human telomeric proteins Pin2 and TRF1 suggest a role in mitosis

1 reference

https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

The essential mitotic peptidyl-prolyl isomerase Pin1 binds and regulates mitosis-specific phosphoproteins

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Telomerase and human tumorigenesis

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Homozygous deletions define a region of 8p23.2 containing a putative tumor suppressor gene

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Detection of telomerase activity in malignant and nonmalignant skin conditions

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Control of telomere length by the human telomeric protein TRF1

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Myc activates telomerase

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Direct activation of TERT transcription by c-MYC.

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Organization and expression of human telomere repeat binding factor genes

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Pif1p helicase, a catalytic inhibitor of telomerase in yeast

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

Pin1-dependent prolyl isomerization regulates dephosphorylation of Cdc25C and tau proteins

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https://api.crossref.org/works/10.1016%2FS0092-8674%2801%2900538-4

7 January 2021

10.1016/S0092-8674(01)00538-4

Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

3529645

3529645

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

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