Fractalkine is expressed by smooth muscle cells in response to IFN-gamma and TNF-alpha and is modulated by metalloproteinase activity (Q24292098)

positive regulation of inflammatory response

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Andreas Ludwig

1

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Theo Berkhout

2

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Kitty Moores

3

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Pieter Groot

4

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Gayle Chapman

Fractalkine and macrophage-derived chemokine: T cell-attracting chemokines expressed in T cell area dendritic cells.

5

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language of work or name

English

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publication date

15 January 2002

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published in

Journal of Immunology

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volume

168

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issue

2

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page(s)

604-12

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cites work

1 reference

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7 January 2021

Fractalkine, a CX3C chemokine, is expressed by dendritic cells and is up-regulated upon dendritic cell maturation

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7 January 2021

The transmembrane form of the CX3CL1 chemokine fractalkine is expressed predominantly by epithelial cells in vivo

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Expression and cellular localization of the CC chemokines PARC and ELC in human atherosclerotic plaques

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The role of fractalkine in the recruitment of monocytes to the endothelium

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Expression of monocyte chemoattractant protein-1 cDNA in vascular smooth muscle cells: induction of the synthetic phenotype: a possible clue to SMC differentiation in the process of atherogenesis

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7 January 2021

Identification and molecular characterization of fractalkine receptor CX3CR1, which mediates both leukocyte migration and adhesion

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Synergistic stimulation, by tumor necrosis factor-alpha and interferon-gamma, of fractalkine expression in human astrocytes

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Structure determination and analysis of human neutrophil collagenase complexed with a hydroxamate inhibitor

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A new class of membrane-bound chemokine with a CX3C motif

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Chemokines and disease

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Chemokines: immunology's high impact factors

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MIP-3alpha, MIP-3beta and fractalkine induce the locomotion and the mobilization of intracellular calcium, and activate the heterotrimeric G proteins in human natural killer cells

1 reference

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7 January 2021

Prevention of crescentic glomerulonephritis by immunoneutralization of the fractalkine receptor CX3CR1 rapid communication

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Bioactive conformation of stromelysin inhibitors determined by transferred nuclear Overhauser effects

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Batimastat, a potent matrix mealloproteinase inhibitor, exhibits an unexpected mode of binding

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Role for neuronally derived fractalkine in mediating interactions between neurons and CX3CR1-expressing microglia

1 reference

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Cloning, in vitro expression, and functional characterization of a novel human CC chemokine of the monocyte chemotactic protein (MCP) family (MCP-4) that binds and signals through the CC chemokine receptor 2B

1 reference

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7 January 2021

Identification of CX3CR1. A chemotactic receptor for the human CX3C chemokine fractalkine and a fusion coreceptor for HIV-1

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7 January 2021

Molecular uncoupling of fractalkine-mediated cell adhesion and signal transduction. Rapid flow arrest of CX3CR1-expressing cells is independent of G-protein activation

1 reference

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7 January 2021

Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates the cleavage and shedding of fractalkine (CX3CL1)

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7 January 2021

Fractalkine and CX3CR1 mediate a novel mechanism of leukocyte capture, firm adhesion, and activation under physiologic flow

1 reference

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7 January 2021

Expression of a disintegrin-like protein in cultured human vascular cells and in vivo.

1 reference

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Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion

1 reference

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Generation and analysis of mice lacking the chemokine fractalkine

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Expression of monocyte chemotactic protein and interleukin-8 by cytokine-activated human vascular smooth muscle cells

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Linked Chromosome 16q13 Chemokines, Macrophage-Derived Chemokine, Fractalkine, and Thymus- and Activation-Regulated Chemokine, Are Expressed in Human Atherosclerotic Lesions

1 reference

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Overexpression of eotaxin and the CCR3 receptor in human atherosclerosis: using genomic technology to identify a potential novel pathway of vascular inflammation

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Evidence for altered balance between matrix metalloproteinases and their inhibitors in human aortic diseases

1 reference

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The stromal cell-derived factor-1 chemokine is a potent platelet agonist highly expressed in atherosclerotic plaques.

1 reference

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Association between polymorphism in the chemokine receptor CX3CR1 and coronary vascular endothelial dysfunction and atherosclerosis

1 reference

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Fractalkine (CX3CL1) as an amplification circuit of polarized Th1 responses.

1 reference

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Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques

1 reference

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Polymorphism in the fractalkine receptor CX3CR1 as a genetic risk factor for coronary artery disease

1 reference

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Fractalkine cleavage from neuronal membranes represents an acute event in the inflammatory response to excitotoxic brain damage

1 reference

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Fractalkine is an epithelial and endothelial cell-derived chemoattractant for intraepithelial lymphocytes in the small intestinal mucosa

1 reference

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CX3C-chemokine, fractalkine-enhanced adhesion of THP-1 cells to endothelial cells through integrin-dependent and -independent mechanisms

1 reference

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A role for fractalkine and its receptor (CX3CR1) in cardiac allograft rejection

1 reference

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7 January 2021