Identification of target genes regulated by PAX3 and PAX3-FKHR in embryogenesis and alveolar rhabdomyosarcoma (Q24292357)

positive regulation of transcription by RNA polymerase II

GOA release 2020-03-11

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GOA release 2020-03-11

Paired box 3

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alveolar rhabdomyosarcoma

GOA release 2020-03-11

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4

Frederic G Barr

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author name string

Thomas D Barber

1

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Melisa C Barber

2

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Oana Tomescu

3

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Steve Ruben

5

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Thomas B Friedman

Pax: gene regulators in the developing nervous system.

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language of work or name

English

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publication date

March 2002

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published in

Genomics

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volume

79

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issue

3

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page(s)

278-84

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cites work

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Transforming growth factor alpha.

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https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

bves: A novel gene expressed during coronary blood vessel development

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https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

The splotch-delayed (Spd) mouse mutant carries a point mutation within the paired box of the Pax-3 gene

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https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

The Splotch mutation interferes with muscle development in the limbs

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https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Persistent truncus arteriosus in the Splotch mutant mouse

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https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Genomic organization and chromosomal localization of the Itm2a gene

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https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Cloning and expression of hbves, a novel and highly conserved mRNA expressed in the developing and adult heart and skeletal muscle in the human

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https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Reduced expression of pax-3 is associated with overexpression of cdc46 in the mouse embryo.

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3

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https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Consistent chromosomal translocation in alveolar rhabdomyosarcoma

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https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

CASTing for multicomponent DNA-binding complexes

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https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Development of a lethal congenital heart defect in the splotch (Pax3) mutant mouse.

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Redefining the genetic hierarchies controlling skeletal myogenesis: Pax-3 and Myf-5 act upstream of MyoD.

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Ectopic Pax-3 activates MyoD and Myf-5 expression in embryonic mesoderm and neural tissue

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Purification and characterization of TEF1, a transcription factor that controls the human transforming growth factor-alpha promoter

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

cDNA sequence analysis, chromosomal assignment and expression pattern of the gene coding for integral membrane protein 2B.

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

PAX3 gene structure, alternative splicing and evolution

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https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Pax-3 is necessary but not sufficient for lbx1 expression in myogenic precursor cells of the limb

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https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Chromosomal translocations involving paired box transcription factors in human cancer

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https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Two further cases of t(2;13) in alveolar rhabdomyosarcoma indicating a review of the published chromosome breakpoints

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https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Rearrangement of the PAX3 paired box gene in the paediatric solid tumour alveolar rhabdomyosarcoma

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https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Epistatic relationship between Waardenburg syndrome genes MITF and PAX3

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Definition of a consensus binding site for p53

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Fusion of a fork head domain gene to PAX3 in the solid tumour alveolar rhabdomyosarcoma

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

A mutation within intron 3 of the Pax-3 gene produces aberrantly spliced mRNA transcripts in the splotch (Sp) mouse mutant

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Pax3 modulates expression of the c-Met receptor during limb muscle development

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Fusion genes resulting from alternative chromosomal translocations are overexpressed by gene-specific mechanisms in alveolar rhabdomyosarcoma

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene.

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Isolation of markers for chondro-osteogenic differentiation using cDNA library subtraction. Molecular cloning and characterization of a gene belonging to a novel multigene family of integral membrane proteins

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Transcription factor AP-2 controls transcription of the human transforming growth factor-alpha gene

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Defining target sequences of DNA-binding proteins by random selection and PCR: determination of the GCN4 binding sequence repertoire

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Whole genome PCR: application to the identification of sequences bound by gene regulatory proteins

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Target Detection Assay (TDA): a versatile procedure to determine DNA binding sites as demonstrated on SP1 protein

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

A sensitive method for the determination of protein-DNA binding specificities

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Isolation of genomic DNA fragments corresponding to genes modulated in vivo by a transcription factor.

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Vascular endothelial growth factor (VEGF) and its receptors

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Rat Transforming Growth Factor Type 1: Structure and Relation to Epidermal Growth Factor

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

The GLI gene encodes a nuclear protein which binds specific sequences in the human genome

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

The PAX3-FKHR fusion protein created by the t(2;13) translocation in alveolar rhabdomyosarcomas is a more potent transcriptional activator than PAX3

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

p53 stimulates transcription from the human transforming growth factor alpha promoter: a potential growth-stimulatory role for p53.

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Tumor-specific PAX3-FKHR transcription factor, but not PAX3, activates the platelet-derived growth factor alpha receptor

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

1 reference

7 January 2021

p57Kip2 expression is enhanced during mid-cardiac murine development and is restricted to trabecular myocardium

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021

Transcriptional regulation of the human transforming growth factor-alpha gene

1 reference

https://api.crossref.org/works/10.1006%2FGENO.2002.6703

7 January 2021