E2F-7: a distinctive E2F family member with an unusual organization of DNA-binding domains (Q24292748)

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Jon Wilson

5

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René Bernards

object named as

René Bernards

8

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author name string

Nicola Logan

1

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Laurent Delavaine

2

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Anne Graham

3

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Carmel Reilly

4

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Thijn R Brummelkamp

6

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E Marielle Hijmans

7

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Nicholas B La Thangue

Transcription factor E2F-1 is upregulated in response to DNA damage in a manner analogous to that of p53

9

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language of work or name

English

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publication date

1 July 2004

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published in

Oncogene

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volume

23

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issue

30

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page(s)

5138-50

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cites work

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E2F7, a novel E2F featuring DP-independent repression of a subset of E2F-regulated genes

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DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?

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The regulation of E2F by pRB-family proteins

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E2F4 and E2F5 play an essential role in pocket protein-mediated G1 control

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The Hallmarks of Cancer

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E2F4 is essential for normal erythrocyte maturation and neonatal viability

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Crystal structure of a prokaryotic replication initiator protein bound to DNA at 2.6 Å resolution

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E2Ls, E2F-like repressors of Arabidopsis that bind to E2F sites in a monomeric form

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Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase

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An adenovirus E1A-like transcription factor is regulated during the differentiation of murine embryonal carcinoma stem cells

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Purification and characterization of a CENP-B homologue protein that binds to the centromeric K-type repeat DNA of Schizosaccharomyces pombe

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A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells

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Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis

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Loss of E2F4 activity leads to abnormal development of multiple cellular lineages

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SWISS-MODEL: An automated protein homology-modeling server

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Deregulated expression of E2F-1 induces S-phase entry and leads to apoptosis

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E2F and cell cycle control: a double-edged sword

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Chk2 activates E2F-1 in response to DNA damage

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Sibling rivalry in the E2F family

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The E2F1-3 transcription factors are essential for cellular proliferation.

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Structural basis of DNA recognition by the heterodimeric cell cycle transcription factor E2F-DP

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Apaf-1 is a transcriptional target for E2F and p53

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Functional synergy between DP-1 and E2F-1 in the cell cycle-regulating transcription factor DRTF1/E2F.

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E2F-1 functions in mice to promote apoptosis and suppress proliferation

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Oct-1 POU domain-DNA interactions: cooperative binding of isolated subdomains and effects of covalent linkage

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Regulation of E2F transcription by cyclin E-Cdk2 kinase mediated through p300/CBP co-activators

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Tumor induction and tissue atrophy in mice lacking E2F-1

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