HSPC117 is the essential subunit of a human tRNA splicing ligase complex (Q24292894)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0072669

RNA transcription, translation and transport factor

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Chromosome 2 open reading frame 49

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RNA 2',3'-cyclic phosphate and 5'-OH ligase

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DEAD-box helicase 1

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Family with sequence similarity 98 member B

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author

Reinhard Georg Lührmann

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Dieter Söll

10

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Karl Mechtler

6

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Simon Trowitzsch

7

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Beata Mierzwa

object named as

Beata Mierzwa

5

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Alexander Schleiffer

object named as

Alexander Schleiffer

4

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Cindy L Will

8

object named as

Cindy L Will

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author name string

Johannes Popow

1

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Markus Englert

2

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Stefan Weitzer

3

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Javier Martinez

Identification of a human endonuclease complex reveals a link between tRNA splicing and pre-mRNA 3' end formation

11

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language of work or name

English

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publication date

11 February 2011

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published in

Science

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volume

331

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issue

6018

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page(s)

760-4

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cites work

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https://api.crossref.org/works/10.1126/SCIENCE.1197847

The yeast tRNA splicing endonuclease: a tetrameric enzyme with two active site subunits homologous to the archaeal tRNA endonucleases

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1197847

Plant tRNA ligases are multifunctional enzymes that have diverged in sequence and substrate specificity from RNA ligases of other phylogenetic origins

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1197847

RNA 3'-terminal phosphate cyclase activity and RNA ligation in HeLa cell extract

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1197847

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1197847

The human RNA kinase hClp1 is active on 3' transfer RNA exons and short interfering RNAs

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1197847

An intact unfolded protein response in Trpt1 knockout mice reveals phylogenic divergence in pathways for RNA ligation

20 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCIENCE.1197847

tRNA biology charges to the front

20 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1197847

Crystal structure of an RtcB homolog protein (PH1602-extein protein) from Pyrococcus horikoshii reveals a novel fold

20 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1197847

7 January 2021

Exploiting 3D structural templates for detection of metal-binding sites in protein structures

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1197847

7 January 2021

Origin of splice junction phosphate in tRNAs processed by HeLa cell extract

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1197847

7 January 2021

Junction phosphate is derived from the precursor in the tRNA spliced by the archaeon Haloferax volcanii cell extract

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1197847

7 January 2021

Formation of a 2′-phosphomonoester, 3′,5′-phosphodiester linkage by a novel RNA ligase in wheat germ

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1197847

7 January 2021

Isolation and characterization of an RNA ligase from HeLa cells.

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1197847

7 January 2021

A host-specific function is required for ligation of a wide variety of ribozyme-processed RNAs

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1197847

7 January 2021

https://api.crossref.org/works/10.1126%2FSCIENCE.1197847

1 reference

7 January 2021

Characterization of the Escherichia coli RNA 3'-terminal phosphate cyclase and its sigma54-regulated operon.

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1197847

7 January 2021

Mutational analysis of bacteriophage T4 RNA ligase 1. Different functional groups are required for the nucleotidyl transfer and phosphodiester bond formation steps of the ligation reaction

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1197847

7 January 2021

Genetic and biochemical analysis of the functional domains of yeast tRNA ligase

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1197847

7 January 2021

DNA-bound transcription factor complexes analysed by mass-spectrometry: binding of novel proteins to the human c-fos SRE and related sequences

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1197847

7 January 2021

'Conserved hypothetical' proteins: prioritization of targets for experimental study

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1197847

7 January 2021

Purification of RNA 3'-terminal-phosphate cyclase from HeLa cells. Covalent modification of the enzyme with different nucleotides

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1197847

7 January 2021

Conserved mechanism of tRNA splicing in eukaryotes

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1197847

7 January 2021

Combined proteomic-RNAi screen for host factors involved in human hepatitis delta virus replication

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1197847

7 January 2021