Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics (Q24292910)

Phosphopantothenoylcysteine decarboxylase

ChEBI release 2020-05-28

ChEBI ID

15346

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Coenzyme A synthase

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Phosphopantothenoylcysteine synthetase

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coenzyme A biosynthetic process

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Phosphopantothenate--cysteine ligase CAB2 YIL083C

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Putative pantetheine-phosphate adenylyltransferase YGR277C

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7

Andrei Osterman

Andrei

Osterman

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26 October 2023

Matthew Daugherty

1

Matthew

Daugherty

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26 October 2023

Boris Polanuyer

2

Boris

Polanuyer

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26 October 2023

Michael Farrell

3

Michael

Farrell

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26 October 2023

Michael Scholle

4

Michael

Scholle

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26 October 2023

Athanasios Lykidis

5

Athanasios

Lykidis

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26 October 2023

Valerie de Crécy-Lagard

6

Valerie

Journal of Biological Chemistry

de Crécy-Lagard

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26 October 2023

language of work or name

English

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publication date

14 June 2002

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published in

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volume

277

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page(s)

21431-9

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issue

24

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cites work

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A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome

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Cloning, sequencing, and expression of the pantothenate kinase (coaA) gene of Escherichia coli

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Molecular characterization of lantibiotic-synthesizing enzyme EpiD reveals a function for bacterial Dfp proteins in coenzyme A biosynthesis

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Phosphopantothenoylcysteine synthetase from Escherichia coli. Identification and characterization of the last unidentified coenzyme A biosynthetic enzyme in bacteria

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Purification and characterization of phosphopantetheine adenylyltransferase from Escherichia coli

21 January 2018

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Identification of yacE (coaE) as the structural gene for dephosphocoenzyme A kinase in Escherichia coli K-12.

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Pantothenate kinase regulation of the intracellular concentration of coenzyme A.

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Cloning and characterization of a eukaryotic pantothenate kinase gene (panK) from Aspergillus nidulans

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Archaeal shikimate kinase, a new member of the GHMP-kinase family

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A continuous spectrophotometric assay for argininosuccinate synthetase based on pyrophosphate formation

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A bifunctional enzyme complex in coenzyme A biosynthesis: purification of pantetheine phosphate adenylyltransferase and dephospho-CoA kinase

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Arabidopsis thaliana flavoprotein AtHAL3a catalyzes the decarboxylation of 4'-Phosphopantothenoylcysteine to 4'-phosphopantetheine, a key step in coenzyme A biosynthesis

21 January 2018

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Arabidopsis thaliana AtHAL3: a flavoprotein related to salt and osmotic tolerance and plant growth.

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The X-ray structure of the FMN-binding protein AtHal3 provides the structural basis for the activity of a regulatory subunit involved in signal transduction

21 January 2018

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Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysis

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Site-selected mutagenesis of a conserved nucleotide binding HXGH motif located in the ATP sulfurylase domain of human bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase

21 January 2018

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The cytidylyltransferase superfamily: identification of the nucleotide-binding site and fold prediction

21 January 2018

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The crystal structure of a novel bacterial adenylyltransferase reveals half of sites reactivity

21 January 2018

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45 Phosphopantothenoylcysteine decarboxylase from horse liver 4′-phospho-N-(d-pantothenoyl)-l-cysteine carboxy-lyase, EC 4.1.1.36

21 January 2018

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Mechanistic studies on phosphopantothenoylcysteine decarboxylase

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Synthesis and antitumor activity of an inhibitor of fatty acid synthase

21 January 2018

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Human placental Na+-dependent multivitamin transporter. Cloning, functional expression, gene structure, and chromosomal localization

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The winds of (evolutionary) change: breathing new life into microbiology

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Coenzyme a-synthesizing protein complex of Saccharomyces cerevisiae

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7 January 2021

Pantothenic acid in health and disease.

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7 January 2021

Investigations on Pantothenic Acid and Its Related Compounds: IX. Biochemical Studies (4).* Separation and Substrate Specificity of Pantothenate Kinase and Phosphopantothenoylcysteine Synthetase**

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7 January 2021

Investigations on Pantothenic Acid and Its Related Compounds: X. Biochemical Studies (5).* Purification and Substrate Specificity of Phosphopantothenoylcysteine Decarboxylase from Rat Liver**

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7 January 2021

Mitochondrial pantetheinephosphate adenylyltransferase and dephospho-CoA kinase

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7 January 2021