Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth (Q24293042)

19

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Gregory D. Plowman

object named as

Greg Plowman

14

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author name string

Qi Pan

1

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Yvan Chanthery

2

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Wei-Ching Liang

3

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Scott Stawicki

4

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Judy Mak

5

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Nisha Rathore

6

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Raymond K Tong

7

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Joe Kowalski

8

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Sharon Fong Yee

9

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Glenn Pacheco

10

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Sarajane Ross

11

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Zhiyong Cheng

12

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Jennifer Le Couter

13

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Franklin Peale

15

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Alexander W Koch

16

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Yan Wu

17

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Anil Bagri

18

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Ryan J Watts

Neuropilin 1 and neuropilin 2 co-expression is significantly correlated with increased vascularity and poor prognosis in nonsmall cell lung carcinoma

20

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language of work or name

English

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publication date

January 2007

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published in

Cancer Cell

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volume

11

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issue

1

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page(s)

53-67

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VEGF-receptor signal transduction

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Overexpression of neuropilin-1 promotes constitutive MAPK signalling and chemoresistance in pancreatic cancer cells

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p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells.

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Autophosphorylation of KDR in the kinase domain is required for maximal VEGF-stimulated kinase activity and receptor internalization

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VEGF activates protein kinase C-dependent, but Ras-independent Raf-MEK-MAP kinase pathway for DNA synthesis in primary endothelial cells

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Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells

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Characterization of a Bicyclic Peptide Neuropilin-1 (NP-1) Antagonist (EG3287) Reveals Importance of Vascular Endothelial Growth Factor Exon 8 for NP-1 Binding and Role of NP-1 in KDR Signaling

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Neuropilin-1 suppresses tumorigenic properties in a human pancreatic adenocarcinoma cell line lacking neuropilin-1 coreceptors

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Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors

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