Structural insights into the Slit-Robo complex (Q24293266)

Roundabout guidance receptor 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

LRR domain binding

1 reference

GOA release 2020-03-11

author

Stephen Anthony Cusack

7

0 references

Cécile Morlot

object named as

Cecile Morlot

1

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Nicole Thielens

object named as

Nicole M Thielens

2

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author name string

Raimond B G Ravelli

3

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Wieger Hemrika

4

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Roland A Romijn

5

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Piet Gros

6

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Andrew A McCarthy

Proceedings of the National Academy of Sciences of the United States of America

8

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language of work or name

English

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publication date

18 September 2007

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published in

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volume

104

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issue

38

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page(s)

14923-8

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cites work

A molecular mechanism for the heparan sulfate dependence of slit-robo signaling

1 reference

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Binding site for Robo receptors revealed by dissection of the leucine-rich repeat region of Slit

19 March 2017

1 reference

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Extracellular Ig domains 1 and 2 of Robo are important for ligand (Slit) binding

19 March 2017

1 reference

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Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain

19 March 2017

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19 March 2017

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Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin

19 March 2017

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Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization

19 March 2017

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Crystal structure of nerve growth factor in complex with the ligand-binding domain of the TrkA receptor

19 March 2017

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Slit proteins bind Robo receptors and have an evolutionarily conserved role in repulsive axon guidance

19 March 2017

1 reference

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Cloning and expressions of three mammalian homologues of Drosophila slit suggest possible roles for Slit in the formation and maintenance of the nervous system

19 March 2017

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The DUTT1 gene, a novel NCAM family member is expressed in developing murine neural tissues and has an unusually broad pattern of expression

19 March 2017

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Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors

19 March 2017

1 reference

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Production of Slit2 LRR domains in mammalian cells for structural studies and the structure of human Slit2 domain 3

19 March 2017

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Structure of the Nogo receptor ectodomain: a recognition module implicated in myelin inhibition

19 March 2017

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The crystal structure of the ligand binding module of axonin-1/TAG-1 suggests a zipper mechanism for neural cell adhesion

19 March 2017

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A dimeric crystal structure for the N-terminal two domains of intercellular adhesion molecule-1

19 March 2017

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The CCP4 suite: programs for protein crystallography

19 March 2017

1 reference

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Substructure solution with SHELXD

19 March 2017

2 references

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Identification of ROBO1 as a novel hepatocellular carcinoma antigen and a potential therapeutic and diagnostic target

22 April 2017

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19 March 2017

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Evidence for the existence of two Robo3 isoforms with divergent biochemical properties

7 April 2017

1 reference

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The divergent Robo family protein rig-1/Robo3 is a negative regulator of slit responsiveness required for midline crossing by commissural axons

19 March 2017

1 reference

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Robo4 is a vascular-specific receptor that inhibits endothelial migration

19 March 2017

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Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis

19 March 2017

1 reference

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Diversity and specificity of actions of Slit2 proteolytic fragments in axon guidance

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1975871

Hierarchical organization of guidance receptors: silencing of netrin attraction by slit through a Robo/DCC receptor complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1975871

Vertebrate slit, a secreted ligand for the transmembrane protein roundabout, is a repellent for olfactory bulb axons

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1975871

Biochemical purification of a mammalian slit protein as a positive regulator of sensory axon elongation and branching

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1975871

Cloning, expression, crystallization and preliminary X-ray analysis of the first two Ig domains from human roundabout 1 (Robo1).

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1975871

Regulation of commissural axon pathfinding by slit and its Robo receptors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1975871

Lateral positioning at the dorsal midline: Slit and Roundabout receptors guide Drosophila heart cell migration

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1975871

Potential role of the Slit/Robo signal pathway in angiogenesis.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1975871

Common mechanisms of nerve and blood vessel wiring

27 September 2017

1 reference

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Axon guidance at the midline: from mutants to mechanisms

27 September 2017

1 reference

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Slit protein-mediated inhibition of CXCR4-induced chemotactic and chemoinvasive signaling pathways in breast cancer cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1975871

Ligand-binding sites in Ig-like domains of receptor tyrosine kinases.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1975871

Modularity of the slit protein. Characterization of a conserved carboxy-terminal sequence in secreted proteins and a motif implicated in extracellular protein interactions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1975871

Slit and Robo control cardiac cell polarity and morphogenesis

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1975871

[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods.

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17848514

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Structure of the Nogo Receptor Ectodomain

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0705310104

inferred from DOI database lookup

7 January 2021

based on heuristic

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0705310104

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1073/PNAS.0705310104

1 reference

ADS bibcode

2007PNAS..10414923M

0 references

1 reference

1 reference

PubMed publication ID

17848514

1 reference