Structural basis for AMP binding to mammalian AMP-activated protein kinase (Q24293456)

12

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author name string

Bing Xiao

1

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Richard Heath

2

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Peter Saiu

3

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Fiona C Leiper

4

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Philippe Leone

5

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Chun Jing

6

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Philip A Walker

7

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Lesley Haire

8

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John F Eccleston

9

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Colin T Davis

10

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Stephen R Martin

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

11

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language of work or name

English

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publication date

27 September 2007

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published in

Nature

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volume

449

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issue

7161

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page(s)

496-500

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cites work

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The AMP-activated/SNF1 protein kinase subfamily: metabolic sensors of the eukaryotic cell?

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The AMP-activated protein kinase--fuel gauge of the mammalian cell?

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AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus

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The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity

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AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

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Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

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Adiponectin stimulates glucose utilization and fatty-acid oxidation by activating AMP-activated protein kinase

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CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK.

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Role of AMP-activated protein kinase in mechanism of metformin action

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The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

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Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade

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The AMP-activated protein kinase cascade--a unifying system for energy control

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Characterization of AMP-activated protein kinase beta and gamma subunits. Assembly of the heterotrimeric complex in vitro

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A novel domain in AMP-activated protein kinase causes glycogen storage bodies similar to those seen in hereditary cardiac arrhythmias.

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7 January 2021

AMP-activated protein kinase beta subunit tethers alpha and gamma subunits via its C-terminal sequence (186-270)

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7 January 2021

Crystal structures of the adenylate sensor from fission yeast AMP-activated protein kinase

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7 January 2021

Crystal structure of the protein kinase domain of yeast AMP-activated protein kinase Snf1.

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7 January 2021

CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations

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7 January 2021

AMPK signaling in contracting human skeletal muscle: acetyl-CoA carboxylase and NO synthase phosphorylation

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7 January 2021

Exercise induces isoform-specific increase in 5'AMP-activated protein kinase activity in human skeletal muscle.

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7 January 2021

Short-term exercise training in humans reduces AMPK signalling during prolonged exercise independent of muscle glycogen

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7 January 2021

The Anti-diabetic drugs rosiglitazone and metformin stimulate AMP-activated protein kinase through distinct signaling pathways.

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Identification of a gene responsible for familial Wolff-Parkinson-White syndrome

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Mutations in the gamma(2) subunit of AMP-activated protein kinase cause familial hypertrophic cardiomyopathy: evidence for the central role of energy compromise in disease pathogenesis

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7 January 2021

Intrasteric control of AMPK via the gamma1 subunit AMP allosteric regulatory site

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7 January 2021

Mammalian AMP-activated protein kinase: functional, heterotrimeric complexes by co-expression of subunits in Escherichia coli

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7 January 2021

AMoRe: an automated package for molecular replacement

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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Improved methods for building protein models in electron density maps and the location of errors in these models

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Fluorescent nucleotide analogs: synthesis and applications

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Identifiers

DOI

10.1038/NATURE06161

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

4865623

1020978255

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Fatcat ID

release_lra5g4fptfgnpl62b33f4uk4bu

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4865623

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference