Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected] (Q24293493)

co-SMAD binding

1 reference

SMAD family member 4

1 reference

Inhibitor of DNA binding 2

1 reference

GATA binding protein 4

1 reference

14

Christine E Seidman

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author name string

Ivan P Moskowitz

1

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Jun Wang

2

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Michael A Peterson

3

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William T Pu

4

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Alexander C Mackinnon

5

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Leif Oxburgh

6

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Gerald C Chu

7

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Molly Sarkar

8

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Charles Berul

9

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Leslie Smoot

10

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Elizabeth J Robertson

11

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Robert Schwartz

12

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Jonathan G Seidman

Proceedings of the National Academy of Sciences of the United States of America

13

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language of work or name

English

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publication date

8 March 2011

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published in

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volume

108

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issue

10

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page(s)

4006-11

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cites work

Mutations in NOTCH1 cause aortic valve disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

GATA4 mutations cause human congenital heart defects and reveal an interaction with TBX5

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Proper coronary vascular development and heart morphogenesis depend on interaction of GATA-4 with FOG cofactors

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Requirement of type III TGF-beta receptor for endocardial cell transformation in the heart

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Congenital heart disease caused by mutations in the transcription factor NKX2-5

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Mutations in human TBX5 [corrected] cause limb and cardiac malformation in Holt-Oram syndrome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Holt-Oram syndrome is caused by mutations in TBX5, a member of the Brachyury (T) gene family

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Tgfbeta signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Hematopoiesis controlled by distinct TIF1gamma and Smad4 branches of the TGFbeta pathway

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

GATA4 is a dosage-sensitive regulator of cardiac morphogenesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Rescue of cardiac defects in id knockout embryos by injection of embryonic stem cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

An essential role of Bmp4 in the atrioventricular septation of the mouse heart

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Mice lacking Bmp6 function

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Tie2-Cre transgenic mice: a new model for endothelial cell-lineage analysis in vivo

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Cx30.2 enhancer analysis identifies Gata4 as a novel regulator of atrioventricular delay

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Endoglin and Alk5 regulate epithelial-mesenchymal transformation during cardiac valve formation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Myocardin sumoylation transactivates cardiogenic genes in pluripotent 10T1/2 fibroblasts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Cell biology of cardiac cushion development.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

1274 full-open reading frames of transcripts expressed in the developing mouse nervous system

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Heart valve development: endothelial cell signaling and differentiation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

SUMO-1 modification activated GATA4-dependent cardiogenic gene activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Id2 and Id3 define the potency of cell proliferation and differentiation responses to transforming growth factor beta and bone morphogenetic protein.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

The cardiac determination factor, Nkx2-5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Combinatorial expression of GATA4, Nkx2-5, and serum response factor directs early cardiac gene activity.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Targeted disruption in murine cells reveals variable requirement for Smad4 in transforming growth factor beta-related signaling.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3053967

Dynamic patterns of expression of BMP isoforms 2, 4, 5, 6, and 7 during chicken heart development

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1019025108

Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1019025108

Essential functions of Alk3 during AV cushion morphogenesis in mouse embryonic hearts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1019025108

Bmp6 and Bmp7 are required for cushion formation and septation in the developing mouse heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1019025108

CRELD1 andGATA4 gene analysis in patients with nonsyndromic atrioventricular canal defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1019025108

Genetic aspects of atrioventricular septal defects

21 January 2018

1 reference

12 December 2020

Generation of Smad4/Dpc4 conditional knockout mice

1 reference

12 December 2020

Invasion of mesenchyme into three-dimensional collagen gels: a regional and temporal analysis of interaction in embryonic heart tissue

1 reference

12 December 2020

Epithelial-mesenchymal cell transformation in the embryonic heart can be mediated, in part, by transforming growth factor beta

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1019025108

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2420352

ADS bibcode

2011PNAS..108.4006M

0 references

OpenCitations bibliographic resource ID

2420352

1 reference