Coupling endoplasmic reticulum stress to the cell death program: role of the ER chaperone GRP78 (Q24293643)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1990001

Heat shock protein family A (Hsp70) member 5

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GOA release 2020-03-11

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8

Lisa M Ellerby

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author name string

Rammohan V Rao

1

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Alyson Peel

2

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Anna Logvinova

3

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Gabriel del Rio

4

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Evan Hermel

5

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Takanori Yokota

6

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Paul C Goldsmith

7

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H Michael Ellerby

9

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Dale E Bredesen

An alternative, nonapoptotic form of programmed cell death

10

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language of work or name

English

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publication date

13 March 2002

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published in

FEBS Letters

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volume

514

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issue

2-3

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page(s)

122-8

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cites work

1 reference

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TRAF family proteins interact with the common neurotrophin receptor and modulate apoptosis induction

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The endoplasmic reticulum chaperone glycoprotein GRP94 with Ca(2+)-binding and antiapoptotic properties is a novel proteolytic target of calpain during etoposide-induced apoptosis

19 March 2017

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An APAF-1.cytochrome c multimeric complex is a functional apoptosome that activates procaspase-9

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150-kDa oxygen-regulated protein (ORP150) suppresses hypoxia-induced apoptotic cell death

19 March 2017

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Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

19 March 2017

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Purification and cDNA cloning of a second apoptosis-related cysteine protease that cleaves and activates sterol regulatory element binding proteins

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Negative regulation of the Apaf-1 apoptosome by Hsp70

19 March 2017

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Intracellular localization of processing events in human surfactant protein B biosynthesis

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19 March 2017

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Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls

19 March 2017

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Major histocompatibility class one molecule associates with glucose regulated protein (GRP) 78 on the cell surface

7 April 2017

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Coupling endoplasmic reticulum stress to the cell death program. Mechanism of caspase activation

27 September 2017

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Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases

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Dependence of vital cell function on endoplasmic reticulum calcium levels: implications for the mechanisms underlying neuronal cell injury in different pathological states

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Hsp27 negatively regulates cell death by interacting with cytochrome c.

27 September 2017

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Heat-shock protein 70 inhibits apoptosis by preventing recruitment of procaspase-9 to the Apaf-1 apoptosome

27 September 2017

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KDEL proteins are found on the surface of NG108-15 cells

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Brefeldin A-mediated apoptosis requires the activation of caspases and is inhibited by Bcl-2.

27 September 2017

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Endoplasmic reticulum chaperones GRP78 and calreticulin prevent oxidative stress, Ca2+ disturbances, and cell death in renal epithelial cells

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27 September 2017

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In vivo expression of mammalian BiP ATPase mutants causes disruption of the endoplasmic reticulum

27 September 2017

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Cross-talk between two cysteine protease families. Activation of caspase-12 by calpain in apoptosis

27 September 2017

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Anti-cancer activity of targeted pro-apoptotic peptides

30 May 2018

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Endoplasmic reticulum stress proteins block oxidant-induced Ca2+ increases and cell death.

30 May 2018

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30 May 2018

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Complex, two-way traffic of molecules across the membrane of the endoplasmic reticulum

30 May 2018

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The endoplasmic reticulum stress-responsive protein GRP78 protects neurons against excitotoxicity and apoptosis: suppression of oxidative stress and stabilization of calcium homeostasis.

30 May 2018

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Caspases: their intracellular localization and translocation during apoptosis.

21 January 2018

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2-Deoxy-D-glucose protects hippocampal neurons against excitotoxic and oxidative injury: evidence for the involvement of stress proteins.

21 January 2018

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Ligand interactions in the adenosine nucleotide-binding domain of the Hsp90 chaperone, GRP94. I. Evidence for allosteric regulation of ligand binding

7 January 2021

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Immunoglobulin binding protein (BiP) function is required to protect cells from endoplasmic reticulum stress but is not required for the secretion of selective proteins

7 January 2021

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Up-regulation of protein-disulfide isomerase in response to hypoxia/brain ischemia and its protective effect against apoptotic cell death

7 January 2021

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