Lysine glutarylation is a protein posttranslational modification regulated by SIRT5 (Q24293721)

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0061697

peptidyl-lysine deglutarylation

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0061699

protein deglutarylation

2 references

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0061698

2''-O-glutaryl-ADP-D-ribose(3-)

GOA release 2020-03-11

1 reference

ChEBI release 2020-05-28

1 reference

GOA release 2020-03-11

Sirtuin 5

1 reference

GOA release 2020-03-11

14

Andreas S Madsen

Andreas S

Madsen

1 reference

19 October 2023

27

Matthew D Hirschey

Matthew D

Hirschey

1 reference

19 October 2023

22

Donald S Backos

Donald S

Backos

1 reference

19 October 2023

Jennifer Ro

11

Jennifer

Ro

1 reference

19 October 2023

Lunzhi Dai

6

Lunzhi

Dai

1 reference

19 October 2023

Chris Mühlhausen

21

Chris

Mühlhausen

1 reference

19 October 2023

Minjia Tan

1

Minjia

Tan

1 reference

19 October 2023

David B Lombard

26

David B

Lombard

1 reference

19 October 2023

Christian A Olsen

23

Christian A

Olsen

1 reference

19 October 2023

Chao Peng

2

Chao

Peng

1 reference

19 October 2023

Kristin A Anderson

3

Kristin A

Anderson

1 reference

19 October 2023

Peter Chhoy

4

Peter

Chhoy

1 reference

19 October 2023

Zhongyu Xie

5

Zhongyu

Xie

1 reference

19 October 2023

Jeongsoon Park

7

Jeongsoon

Park

1 reference

19 October 2023

Yue Chen

8

Yue

Chen

1 reference

19 October 2023

He Huang

9

He

Huang

1 reference

19 October 2023

Yi Zhang

10

Yi

Zhang

1 reference

19 October 2023

Gregory R Wagner

12

Gregory R

Wagner

1 reference

19 October 2023

Michelle F Green

13

Michelle F

Green

1 reference

19 October 2023

Jessica Schmiesing

15

Jessica

Schmiesing

1 reference

19 October 2023

Brett S Peterson

16

Brett S

Peterson

1 reference

19 October 2023

Guofeng Xu

17

Guofeng

Xu

1 reference

19 October 2023

Olga R Ilkayeva

18

Olga R

Ilkayeva

1 reference

19 October 2023

Michael J Muehlbauer

19

Michael J

Muehlbauer

1 reference

19 October 2023

Thomas Braulke

20

Thomas

Braulke

1 reference

19 October 2023

Peter J McGuire

24

Peter J

McGuire

1 reference

19 October 2023

Scott D Pletcher

25

Scott D

Pletcher

1 reference

19 October 2023

Yingming Zhao

28

Yingming

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways

Zhao

1 reference

19 October 2023

language of work or name

English

0 references

publication date

1 April 2014

0 references

published in

Cell Metabolism

0 references

volume

19

0 references

page(s)

605-17

0 references

issue

4

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Sirt5 is a NAD-dependent protein lysine demalonylase and desuccinylase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

The first identification of lysine malonylation substrates and its regulatory enzyme

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Carbamoyl phosphate synthetase: closure of the B-domain as a result of nucleotide binding

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Nucleocytosolic acetyl-coenzyme a synthetase is required for histone acetylation and global transcription

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Histone demethylation by a family of JmjC domain-containing proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

The complex language of chromatin regulation during transcription

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Substrate and functional diversity of lysine acetylation revealed by a proteomics survey

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Isolation and characterization of a naturally occurring cofactor of carbamyl phosphate biosynthesis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

AMPK: a nutrient and energy sensor that maintains energy homeostasis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

ATP-citrate lyase links cellular metabolism to histone acetylation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Protein structure modeling with MODELLER

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Lysine succinylation is a frequently occurring modification in prokaryotes and eukaryotes and extensively overlaps with acetylation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Widespread and enzyme-independent Nε-acetylation and Nε-succinylation of proteins in the chemical conditions of the mitochondrial matrix

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Mechanistic insights into the regulation of metabolic enzymes by acetylation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Human carbamoyl phosphate synthetase I (CPSI): insights on the structural role of the unknown function domains

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Lysine succinylation and lysine malonylation in histones.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Sirtuins mediate mammalian metabolic responses to nutrient availability

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Identification of lysine succinylation as a new post-translational modification

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Chemical phylogenetics of histone deacetylases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Lysine propionylation and butyrylation are novel post-translational modifications in histones

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Fatty acid biosynthesis in wallerian degeneration of rat sciatic nerve

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Metabolic regulation of epigenetics

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Regulation of phosphofructokinase by a new mechanism. An activation factor binding to phosphorylated enzyme.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Malonate, malonyl-coenzyme A, and acetyl-coenzyme A in developing rat brain.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Altered arginine metabolism in the central nervous system (CNS) of the Cln3-/- mouse model of juvenile Batten disease

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Integrated approach for manual evaluation of peptides identified by searching protein sequence databases with tandem mass spectra.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Coenzyme specificity of Sir2 protein deacetylases: implications for physiological regulation

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Biochemical, pathologic and behavioral analysis of a mouse model of glutaric acidemia type I.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4108075

Structure and function of carbamoylphosphate synthase. I. Transitions between two catalytically inactive forms and the active form

29 November 2018

1 reference

12 December 2020

Substrates for efficient fluorometric screening employing the NAD-dependent sirtuin 5 lysine deacylase (KDAC) enzyme

1 reference

12 December 2020

Channeling of ammonia from glutaminase to carbamoyl-phosphate synthetase in liver mitochondria

1 reference

12 December 2020

A rapid colorimetric assay for carbamyl phosphate synthetase I

1 reference

12 December 2020

10.1016/J.CMET.2014.03.014

Identifiers

DOI

1 reference

release_fdequtsbjred7f2bzkerbq2j2q

1374354

Fatcat ID

0 references

1374354

1 reference

1 reference

1 reference