LAAT-1 is the lysosomal lysine/arginine transporter that maintains amino acid homeostasis (Q24294168)

L-arginine transmembrane transport from lysosomal lumen to cytosol

GO:1902022

1 reference

L-arginine transmembrane transport

GO:1904917

1 reference

transmembrane L-cystine transport from lysosomal lumen to cytosol

GO:1902023

1 reference

transmembrane L-lysine transport from lysosomal lumen to cytosol

GO:1904919

1 reference

GO:1904916

L-histidine transport

1 reference

transmembrane L-histidine transport from lysosomal lumen to cytosol

GO:1902024

1 reference

Solute carrier family 66 member 1

GO:1904918

1 reference

amino acid homeostasis

1 reference

Cystinosin homolog CELE_C41C4.7

1 reference

Lysosomal amino acid transporter 1 CELE_Y43H11AL.2

1 reference

Bin Liu

1

0 references

Anton Gartner

object named as

Anton Gartner

4

0 references

author name string

Hongwei Du

2

0 references

Rachael Rutkowski

3

0 references

Xiaochen Wang

The histidyl-tRNA synthetase-related sequence in the eIF-2 alpha protein kinase GCN2 interacts with tRNA and is required for activation in response to starvation for different amino acids

5

0 references

language of work or name

English

0 references

publication date

20 July 2012

0 references

published in

Science

0 references

volume

337

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issue

6092

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page(s)

351-4

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Cystine transport is defective in isolated leukocyte lysosomes from patients with cystinosis

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

The genetics of Caenorhabditis elegans

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Endocytic sorting and recycling require membrane phosphatidylserine asymmetry maintained by TAT-1/CHAT-1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Cystinosin, the protein defective in cystinosis, is a H(+)-driven lysosomal cystine transporter

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Retromer is required for apoptotic cell clearance by phagocytic receptor recycling

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

C. elegans ced-13 can promote apoptosis and is induced in response to DNA damage

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Autophagy: process and function

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Creation of low-copy integrated transgenic lines in Caenorhabditis elegans

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Sequential action of Caenorhabditis elegans Rab GTPases regulates phagolysosome formation during apoptotic cell degradation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

C. elegans screen identifies autophagy genes specific to multicellular organisms

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Adenine nucleotide translocator cooperates with core cell death machinery to promote apoptosis in Caenorhabditis elegans.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

De Novo identification of single nucleotide mutations in Caenorhabditis elegans using array comparative genomic hybridization

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Sorting of lysosomal proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Molecular physiology and pathophysiology of lysosomal membrane transporters

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Semaphorin controls epidermal morphogenesis by stimulating mRNA translation via eIF2alpha in Caenorhabditis elegans

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

The small GTPase Rab2 functions in the removal of apoptotic cells in Caenorhabditis elegans.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

MVB-12, a fourth subunit of metazoan ESCRT-I, functions in receptor downregulation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Dynamic regulation of caveolin-1 trafficking in the germ line and embryo of Caenorhabditis elegans

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Caenorhabditis elegans functional orthologue of human protein h-mucolipin-1 is required for lysosome biogenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

The GCN2 eIF2alpha kinase is required for adaptation to amino acid deprivation in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

RME-8, a conserved J-domain protein, is required for endocytosis in Caenorhabditis elegans.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Homologues of archaeal rhodopsins in plants, animals and fungi: structural and functional predications for a putative fungal chaperone protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

NUC-1, a caenorhabditis elegans DNase II homolog, functions in an intermediate step of DNA degradation during apoptosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Receptor-mediated endocytosis in the Caenorhabditis elegans oocyte.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Cystine accumulation and loss in normal, heterozygous, and cystinotic fibroblasts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Tissue-specific synthesis of yolk proteins in Caenorhabditis elegans

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Cystinosis. Intracellular cystine depletion by aminothiols in vitro and in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Cysteamine depletes cystinotic leucocyte granular fractions of cystine by the mechanism of disulphide interchange

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

Detection and characterization of carrier-mediated cationic amino acid transport in lysosomes of normal and cystinotic human fibroblasts. Role in therapeutic cystine removal?

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

SEPA-1 mediates the specific recognition and degradation of P granule components by autophagy in C. elegans.

30 May 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1220281

eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1220281

Genome-wide analysis identifies a general requirement for polarity proteins in endocytic traffic

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1220281

Quantitative mass spectrometry identifies insulin signaling targets in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1220281

C. elegans Dynamin mediates the signaling of phagocytic receptor CED-1 for the engulfment and degradation of apoptotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1220281

CED-1 is a transmembrane receptor that mediates cell corpse engulfment in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1220281

Candidate adaptor protein CED-6 promotes the engulfment of apoptotic cells in C. elegans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1220281

Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3432903

[C. elegans: of neurons and genes]

29 November 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCIENCE.1220281

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1220281

1 reference

1 reference

1 reference

PubMed publication ID

22822152

1 reference