d-Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia (Q24294371)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17880399%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

d-Amino acid oxidase and serine racemase in human brain: normal distribution and altered expression in schizophrenia (English)

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7 January 2020

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GOA release 2020-03-11

author

Philip W.J. Burnet

7

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7 January 2020

author name string

Louise Verrall

1

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7 January 2020

Mary Walker

2

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7 January 2020

Nancy Rawlings

3

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7 January 2020

Isabel Benzel

4

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7 January 2020

James N C Kew

5

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7 January 2020

Paul J Harrison

6

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7 January 2020

language of work or name

English

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publication date

1 September 2007

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European Journal of Neuroscience

7 January 2020

published in

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7 January 2020

volume

26

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7 January 2020

issue

6

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7 January 2020

page(s)

1657-1669

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Structural basis of D-DOPA oxidation by D-amino acid oxidase: alternative pathway for dopamine biosynthesis

7 January 2020

cites work

1 reference

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19 March 2017

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Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease

19 March 2017

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Induction of serine racemase by inflammatory stimuli is dependent on AP-1

19 March 2017

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Characterization and localization of a human serine racemase

19 March 2017

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Genetic and physiological data implicating the new human gene G72 and the gene for D-amino acid oxidase in schizophrenia

19 March 2017

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19 March 2017

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D-serine is an endogenous ligand for the glycine site of the N-methyl-D-aspartate receptor

19 March 2017

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19 March 2017

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A genetic variant of the serine racemase gene is associated with schizophrenia

19 March 2017

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Serine racemase protein expression in cortex and hippocampus in schizophrenia

19 March 2017

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Modulation of D-serine levels via ubiquitin-dependent proteasomal degradation of serine racemase

19 March 2017

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Identification of multiple serine racemase (SRR) mRNA isoforms and genetic analyses of SRR and DAO in schizophrenia and D-serine levels

19 March 2017

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D-serine efficacy as add-on pharmacotherapy to risperidone and olanzapine for treatment-refractory schizophrenia

19 March 2017

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Serine racemase modulates intracellular D-serine levels through an alpha,beta-elimination activity

19 March 2017

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The axonal chemorepellant semaphorin 3A is increased in the cerebellum in schizophrenia and may contribute to its synaptic pathology

19 March 2017

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Genes for schizophrenia? Recent findings and their pathophysiological implications

19 March 2017

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Cellular and subcellular distribution of D-aspartate oxidase in human and rat brain

19 March 2017

1 reference

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Cerebellar synaptic protein expression in schizophrenia

19 March 2017

1 reference

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Evidence from gene knockout studies implicates Asc-1 as the primary transporter mediating d-serine reuptake in the mouse CNS

19 March 2017

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High affinity D- and L-serine transporter Asc-1: cloning and dendritic localization in the rat cerebral and cerebellar cortices

19 March 2017

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Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission

19 March 2017

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Purification of serine racemase: biosynthesis of the neuromodulator D-serine

19 March 2017

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Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

19 March 2017

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Evidence for association and epistasis at the DAOA/G30 and D-amino acid oxidase loci in an Irish schizophrenia sample

7 April 2017

1 reference

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Association of schizophrenia with DTNBP1 but not with DAO, DAOA, NRG1 and RGS4 nor their genetic interaction

27 September 2017

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Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia

27 September 2017

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A CSF and postmortem brain study of D-serine metabolic parameters in schizophrenia

27 September 2017

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No association of G72 and D-amino acid oxidase genes with schizophrenia

27 September 2017

1 reference

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Preliminary evidence for a link between schizophrenia and NMDA-glycine site receptor ligand metabolic enzymes, d-amino acid oxidase (DAAO) and kynurenine aminotransferase-1 (KAT-1).

27 September 2017

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G72/G30 in schizophrenia and bipolar disorder: review and meta-analysis

27 September 2017

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Neuron-derived D-serine release provides a novel means to activate N-methyl-D-aspartate receptors.

27 September 2017

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Is the cerebellum relevant in the circuitry of neuropsychiatric disorders?

27 September 2017

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Reduced D-serine to total serine ratio in the cerebrospinal fluid of drug naive schizophrenic patients

27 September 2017

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Is the G72/G30 locus associated with schizophrenia? single nucleotide polymorphisms, haplotypes, and gene expression analysis

27 September 2017

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Glutamate, dopamine, and schizophrenia: from pathophysiology to treatment

27 September 2017

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Bringing order to the glutamate chaos in schizophrenia

27 September 2017

1 reference

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Contribution of astrocytes to hippocampal long-term potentiation through release of D-serine.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121142

Distribution and pharmacology of alanine–serine–cysteine transporter 1 (asc‐1) in rodent brain

27 September 2017

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Decreased serum levels of D-serine in patients with schizophrenia: evidence in support of the N-methyl-D-aspartate receptor hypofunction hypothesis of schizophrenia.

27 September 2017

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Expression of serotonin 5-HT(2A) receptors in the human cerebellum and alterations in schizophrenia

27 September 2017

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Immunohistochemical evidences for localization and production of D-serine in some neurons in the rat brain

27 September 2017

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D-serine added to antipsychotics for the treatment of schizophrenia

27 September 2017

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"Cognitive dysmetria" as an integrative theory of schizophrenia: a dysfunction in cortical-subcortical-cerebellar circuitry?

27 September 2017

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The glutamatergic dysfunction hypothesis for schizophrenia

27 September 2017

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Neuropathology of the cerebellum in schizophrenia--an update: 1996 and future directions

27 September 2017

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D-serine, an endogenous synaptic modulator: localization to astrocytes and glutamate-stimulated release

27 September 2017

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Glutamate receptor dysfunction and schizophrenia

27 September 2017

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Ultrastructural localization of D-amino acid oxidase in microperoxisomes of the rat nervous system

27 September 2017

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Immunocytochemical analysis of D-serine distribution in the mammalian brain reveals novel anatomical compartmentalizations in glia and neurons

27 September 2017

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Regional distribution and postnatal changes of D-amino acids in rat brain.

30 May 2018

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Extracellular concentration of endogenous free D-serine in the rat brain as revealed by in vivo microdialysis

30 May 2018

1 reference

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Free D-serine in post-mortem brains and spinal cords of individuals with and without neuropsychiatric diseases.

30 May 2018

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Localization of D-amino acid oxidase in Bergmann glial cells and astrocytes of rat cerebellum.

30 May 2018

1 reference

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Immunochemical relationship of d-amino acid oxidases in various tissues and animals

30 May 2018

1 reference

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In vivo modulation of N-methyl-D-aspartate receptor-dependent long-term potentiation by the glycine modulatory site

30 May 2018

1 reference

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No association between the serine racemase gene (SRR) and schizophrenia in a German case-control sample.

30 May 2018

1 reference

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Association of DAOA polymorphisms with schizophrenia and clinical symptoms or therapeutic effects.

29 November 2018

1 reference

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Expression of the mRNA and protein of serine racemase in primary cultures of rat neurons.

29 November 2018

1 reference

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D-serine is the dominant endogenous coagonist for NMDA receptor neurotoxicity in organotypic hippocampal slices.

29 November 2018

1 reference

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Dual substrate and reaction specificity in mouse serine racemase: identification of high-affinity dicarboxylate substrate and inhibitors and analysis of the beta-eliminase activity

29 November 2018

1 reference

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MK-801 upregulates the expression of d-amino acid oxidase mRNA in rat brain

29 November 2018

1 reference

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Association of DAAO with schizophrenia in the Chinese population.

29 November 2018

1 reference

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Distribution and MK-801-induced expression of serine racemase mRNA in rat brain by real-time quantitative PCR.

29 November 2018

1 reference

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Glial glutamate transporters limit spillover activation of presynaptic NMDA receptors and influence synaptic inhibition of Purkinje neurons.

29 November 2018

1 reference

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Antipsychotics increase microtubule-associated protein 2 mRNA but not spinophilin mRNA in rat hippocampus and cortex.

29 November 2018

1 reference

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Examination of G72 and D-amino-acid oxidase as genetic risk factors for schizophrenia and bipolar affective disorder.

29 November 2018

1 reference

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Spatiotemporal relationships among D-serine, serine racemase, and D-amino acid oxidase during mouse postnatal development

29 November 2018

1 reference

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Inhibitory action of chlorpromazine on the oxidation of d-amino-acid in the diencephalon part of the brain.

29 November 2018

1 reference

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Long-lasting modulation of synaptic input to Purkinje neurons by Bergmann glia stimulation in rat brain slices

29 November 2018

1 reference

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Effect of the intracerebroventricular and systemic administration of L-serine on the concentrations of D- and L-serine in several brain areas and periphery of rat.

29 November 2018

1 reference

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Determination of free D-aspartic acid, D-serine and D-alanine in the brain of mutant mice lacking D-amino acid oxidase activity.

29 November 2018

1 reference

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Effect of the glycine modulatory site of the N-methyl-D-aspartate receptor on synaptic responses in kitten visual cortex

29 November 2018

1 reference

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Synaptophysin gene expression in schizophrenia. Investigation of synaptic pathology in the cerebral cortex.

29 November 2018

1 reference

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D-serine as a neuromodulator: regional and developmental localizations in rat brain glia resemble NMDA receptors.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121142

The effect of chronic imipramine administration on the densities of 5-HT1A and 5-HT2 receptors and the abundances of 5-HT receptor and transporter mRNA in the cortex, hippocampus and dorsal raphe of three strains of rat.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121142

Distribution of free D-serine in vertebrate brains.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121142

Glutamate stimulates [3H]phorbol 12,13-dibutyrate binding in cultured Bergmann glia cells.

29 November 2018

1 reference

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Anatomical distribution and postnatal changes in endogenous free D-aspartate and D-serine in rat brain and periphery.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121142

Polymorphism in the 5'-promoter region of serine racemase gene in schizophrenia

29 November 2018

1 reference

12 December 2020

Immunochemical properties of D-amino-acid oxidase

1 reference

12 December 2020

Significant support for DAO as a schizophrenia susceptibility locus: examination of five genes putatively associated with schizophrenia

1 reference

12 December 2020

Elevated striatal dopamine levels following administration of D-DOPA and its alpha-keto acid metabolite DHPPA: behavioral and physiological studies in vivo in the rat

1 reference

12 December 2020

Immunocytochemical localization of D-amino acid oxidase in rat brain

1 reference

12 December 2020

D-amino-acid oxidase is confined to the lower brain stem and cerebellum in rat brain: regional differentiation of astrocytes

1 reference

12 December 2020

D-dopa is unidirectionally converted to L-dopa by D-amino acid oxidase, followed by dopa transaminase

1 reference

12 December 2020

Sodium benzoate differentially blocks circling induced by D-and L-dopa in the hemi-parkinsonian rat.

1 reference

12 December 2020

10.1111/J.1460-9568.2007.05769.X

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17880399%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17880399%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

1 reference