A subset of human 35S U5 proteins, including Prp19, function prior to catalytic step 1 of splicing (Q24294927)

GOA release 2020-03-11

author

Reinhard Georg Lührmann

7

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Henning Urlaub

3

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Marc Gentzel

Marc Gentzel

5

0 references

Evgeny Makarov

Evgeny M Makarov

2

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Cindy L Will

4

Cindy L Will

0 references

Matthias Wilm

Matthias Wilm

6

0 references

author name string

Olga V Makarova

Characterization of novel SF3b and 17S U2 snRNP proteins, including a human Prp5p homologue and an SF3b DEAD-box protein

1

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language of work or name

English

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publication date

16 June 2004

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published in

The EMBO Journal

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volume

23

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issue

12

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page(s)

2381-91

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cites work

1 reference

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Large-scale proteomic analysis of the human spliceosome

19 March 2017

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Mammalian PRP4 kinase copurifies and interacts with components of both the U5 snRNP and the N-CoR deacetylase complexes

19 March 2017

1 reference

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Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis

19 March 2017

1 reference

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Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

19 March 2017

1 reference

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Protein 61K, encoded by a gene (PRPF31) linked to autosomal dominant retinitis pigmentosa, is required for U4/U6*U5 tri-snRNP formation and pre-mRNA splicing

19 March 2017

1 reference

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The 65 and 110 kDa SR-related proteins of the U4/U6.U5 tri-snRNP are essential for the assembly of mature spliceosomes

19 March 2017

1 reference

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SMNrp is an essential pre-mRNA splicing factor required for the formation of the mature spliceosome

19 March 2017

1 reference

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Genetic and physical interactions between factors involved in both cell cycle progression and pre-mRNA splicing in Saccharomyces cerevisiae

19 March 2017

1 reference

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Functional analysis of the human CDC5L complex and identification of its components by mass spectrometry

19 March 2017

1 reference

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Association of two nuclear proteins, Npw38 and NpwBP, via the interaction between the WW domain and a novel proline-rich motif containing glycine and arginine

19 March 2017

1 reference

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The human U5-200kD DEXH-box protein unwinds U4/U6 RNA duplices in vitro

19 March 2017

1 reference

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Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

19 March 2017

1 reference

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The Prp19p-associated complex in spliceosome activation

19 March 2017

1 reference

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Characterization of interactions among the Cef1p-Prp19p-associated splicing complex

19 March 2017

1 reference

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Functional and physical interactions between components of the Prp19p-associated complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423283

Cef1p is a component of the Prp19p-associated complex and essential for pre-mRNA splicing

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423283

RNA unwinding in U4/U6 snRNPs requires ATP hydrolysis and the DEIH-box splicing factor Brr2

19 March 2017

1 reference

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Mechanical devices of the spliceosome: motors, clocks, springs, and things

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423283

Yeast precursor mRNA processing protein PRP19 associates with the spliceosome concomitant with or just after dissociation of U4 small nuclear RNA.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423283

Functional association of essential splicing factor(s) with PRP19 in a protein complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423283

Comprehensive proteomic analysis of the human spliceosome

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423283

Evidence that dim1 associates with proteins involved in pre-mRNA splicing, and delineation of residues essential for dim1 interactions with hnRNP F and Npw38/PQBP-1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423283

Allosteric cascade of spliceosome activation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423283

Protein composition of human prespliceosomes isolated by a tobramycin affinity-selection method

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423283

SPF30 is an essential human splicing factor required for assembly of the U4/U5/U6 tri-small nuclear ribonucleoprotein into the spliceosome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423283

Resolution of the mammalian E complex and the ATP-dependent spliceosomal complexes on native agarose mini-gels

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423283

The yeast PRP19 protein is not tightly associated with small nuclear RNAs, but appears to associate with the spliceosome after binding of U2 to the pre-mRNA and prior to formation of the functional spliceosome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423283

RNA-RNA interactions in the spliceosome: unraveling the ties that bind

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423283

Evidence for base-pairing between mammalian U2 and U6 small nuclear ribonucleoprotein particles

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423283

Fission yeast Prp4p kinase regulates pre-mRNA splicing by phosphorylating a non-SR-splicing factor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423283

An RNA switch at the 5' splice site requires ATP and the DEAD box protein Prp28p

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423283

Electrophoretic separation of complexes involved in the splicing of precursors to mRNAs

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=423283

Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome.

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7600241

Stepwise assembly of a pre-mRNA splicing complex requires U-snRNPs and specific intron sequences

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15175653

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dynamic exchanges of RNA interactions leading to catalytic core formation in the U12-dependent spliceosome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15175653

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Specific alterations of U1-C protein or U1 small nuclear RNA can eliminate the requirement of Prp28p, an essential DEAD box splicing factor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15175653