Monoclonal antibody to the type I insulin-like growth factor (IGF-I) receptor blocks IGF-I receptor-mediated DNA synthesis: clarification of the mitogenic mechanisms of IGF-I and insulin in human skin fibroblasts (Q24294943)

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English	Monoclonal antibody to the type I insulin-like growth factor (IGF-I) receptor blocks IGF-I receptor-mediated DNA synthesis: clarification of the mitogenic mechanisms of IGF-I and insulin in human skin fibroblasts	scientific article

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scholarly article

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Monoclonal antibody to the type I insulin-like growth factor (IGF-I) receptor blocks IGF-I receptor-mediated DNA synthesis: clarification of the mitogenic mechanisms of IGF-I and insulin in human skin fibroblasts (English)

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insulin like growth factor 1 receptor

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GOA release 2020-03-11

signal transduction

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GOA release 2020-03-11

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based on heuristic

inferred from title

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based on heuristic

inferred from title

monoclonal antibody

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based on heuristic

inferred from title

Jeffrey Scott Flier

1

object named as

J S Flier

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author name string

P Usher

2

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A C Moses

3

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language of work or name

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publication date

February 1986

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Proceedings of the National Academy of Sciences of the United States of America

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83

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3

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664-8

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Stimulation of glucose incorporation and amino acid transport by insulin and an insulin-like growth factor in fibroblasts with defective insulin receptors cultured from a patient with leprechaunism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

27 September 2017

Direct demonstration of separate receptors for growth and metabolic activities of insulin and multiplication-stimulating activity (an insulinlike growth factor) using antibodies to the insulin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

27 September 2017

Growth-stimulatory actions of insulin in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

27 September 2017

Antireceptor antibodies as probes of insulinlike growth factor receptor structure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

27 September 2017

Receptors for insulinlike growth factor I are defective in fibroblasts cultured from a patient with leprechaunism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

27 September 2017

Monoclonal antibodies to the human insulin receptor block insulin binding and inhibit insulin action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

27 September 2017

Dual regulation of glycogen metabolism by insulin and insulin-like growth factors in human hepatoma cells (HEP-G2). Analysis with an anti-receptor monoclonal antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

27 September 2017

Actions of insulin-like growth factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

27 September 2017

Characterization of antibodies to the insulin receptor: a cause of insulin-resistant diabetes in man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

27 September 2017

Autoantibodies to the insulin receptor. Effect on the insulin-receptor interaction in IM-9 lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

27 September 2017

The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

27 September 2017

Correlation between Thyrotropin-Displacing Activity and Human Thyroid-Stimulating Activity by Immunoglobulins from Patients with Graves' Disease and Other Thyroid Disorders*

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

27 September 2017

Identification of a Receptor for Somatomedin-Like Polypeptides in Human Fibroblasts*

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

27 September 2017

Insulin Receptors in Cultured Human Fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

27 September 2017

The syndromes of insulin resistance and acanthosis nigricans. Insulin-receptor disorders in man.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

27 September 2017

Evidence from monoclonal antibody studies that insulin stimulates deoxyribonucleic acid synthesis through the type I somatomedin receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

27 September 2017

Insulin as a potent, specific growth factor in a rat hepatoma cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

30 May 2018

DNA synthesis in human fibroblasts: stimulation by insulin and by nonsuppressible insulin-like activity (NSILA-S).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

30 May 2018

Primary structure of human insulin-like growth factor II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

30 May 2018

Leprechaunism: studies of the relationship among hyperinsulinism, insulin resistance, and growth retardation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

30 May 2018

Fibroblasts from a Patient with Leprechaunism Are Resistant to Insulin, Epidermal Growth Factor, and Somatomedin C*

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

30 May 2018

Purification of tracer for somatomedin C radioimmunoassay by hydrophobic interaction chromatography.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

29 November 2018

Somatomedin-C stimulates the phosphorylation of the beta-subunit of its own receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

29 November 2018

Monoclonal antibodies to receptors for insulin and somatomedin-C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=322924

29 November 2018

Interrelationships among receptor structures for insulin and peptide growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/3003744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor I/somatomedin-C (IGF-I/SM-C) and glucocorticoids synergistically regulate mitosis in competent human fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/3003744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal anti-epidermal growth factor receptor antibodies which are inhibitors of epidermal growth factor binding and antagonists of epidermal growth factor binding and antagonists of epidermal growth factor-stimulated tyrosine protein kinase acti

1 reference

https://pubmed.ncbi.nlm.nih.gov/3003744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-Like Growth Factor Receptors in Rat Placental Membranes*

1 reference

https://pubmed.ncbi.nlm.nih.gov/3003744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of insulin-like growth Factor ii and multiplication-stimulating activity-stimulated phosphorylation in basolateral membranes from dog kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/3003744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor I/somatomedin C (IGF-I/Sm C): comparison of natural, solid phase synthetic and recombinant DNA analog peptides in two radioligand assays

1 reference

https://pubmed.ncbi.nlm.nih.gov/3003744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of monoclonal antibodies to the IGF-I receptor that inhibit IGF-I binding to human cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/3003744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the Somatomedin-C/Insulin-Like Growth Factor I (SM-C/IGF-I) Receptor on Cultured Human Fibroblast Monolayers: Regulation of Receptor Concentrations by SM-C/IGF-I and Insulin*

1 reference

https://pubmed.ncbi.nlm.nih.gov/3003744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin interactions with liver plasma membranes. Independence of binding of the hormone and its degradation

1 reference

https://pubmed.ncbi.nlm.nih.gov/3003744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and Characterization of Multiplication-Stimulating Activity. Insulin-Like Growth Factors Purified from Rat-Liver-Cell-Conditioned Medium

1 reference

https://pubmed.ncbi.nlm.nih.gov/3003744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of insulin-like actions of anti-insulin receptor antibodies. Effects on insulin binding, insulin degradation, and glycogen synthesis in isolated rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/3003744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interactions of insulin-like growth factors I and II and multiplication-stimulating activity with receptors and serum carrier proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/3003744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Demonstration of two subtypes of insulin-like growth factor receptors by affinity cross-linking

1 reference

https://pubmed.ncbi.nlm.nih.gov/3003744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin stimulates the phosphorylation of the 95,000-dalton subunit of its own receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/3003744

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.83.3.664

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1986PNAS...83..664F

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