Protein-tyrosine kinase and GTPase signals cooperate to phosphorylate and activate Wiskott-Aldrich syndrome protein (WASP)/neuronal WASP (Q24295390)

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Autoinhibition and activation mechanisms of the Wiskott-Aldrich syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

A conserved amphipathic helix in WASP/Scar proteins is essential for activation of Arp2/3 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

The nucleotide switch in Cdc42 modulates coupling between the GTPase-binding and allosteric equilibria of Wiskott-Aldrich syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Integration of multiple signals through cooperative regulation of the N-WASP-Arp2/3 complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

A polybasic motif allows N-WASP to act as a sensor of PIP(2) density

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

EspFU is a translocated EHEC effector that interacts with Tir and N-WASP and promotes Nck-independent actin assembly

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Activation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nucleation by Arp2/3 complex and bacterial actin-based motility

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

GRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

A novel neural Wiskott-Aldrich syndrome protein (N-WASP) binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Sustained activation of N-WASP through phosphorylation is essential for neurite extension

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Phosphorylation of tyrosine 291 enhances the ability of WASp to stimulate actin polymerization and filopodium formation. Wiskott-Aldrich Syndrome protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Fyn and PTP-PEST-mediated regulation of Wiskott-Aldrich syndrome protein (WASp) tyrosine phosphorylation is required for coupling T cell antigen receptor engagement to WASp effector function and T cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Contingent phosphorylation/dephosphorylation provides a mechanism of molecular memory in WASP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Structure of Cdc42 in complex with the GTPase-binding domain of the 'Wiskott-Aldrich syndrome' protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Influence of the C terminus of Wiskott-Aldrich syndrome protein (WASp) and the Arp2/3 complex on actin polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Reprogramming control of an allosteric signaling switch through modular recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

The Cdc42/Rac interactive binding region motif of the Wiskott Aldrich syndrome protein (WASP) is necessary but not sufficient for tight binding to Cdc42 and structure formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Purification and initial characterization of the lymphoid-cell protein-tyrosine kinase p56lck from a baculovirus expression system

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

The YRD motif is a major determinant of substrate and inhibitor specificity in T-cell protein-tyrosine phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Purification and characterization of T cell protein tyrosine phosphatase reveals significant functional homology to protein tyrosine phosphatase-1B

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

A two-state allosteric model for autoinhibition rationalizes WASP signal integration and targeting.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Structural basis of Rho GTPase-mediated activation of the formin mDia1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Structural and mechanistic insights into the interaction between Rho and mammalian Dia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

The mouse Formin mDia1 is a potent actin nucleation factor regulated by autoinhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Cdc42/Rac1-mediated activation primes PAK2 for superactivation by tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

All roads lead to actin: the intimate relationship between TCR signaling and the cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Translocation of N-WASP by nuclear localization and export signals into the nucleus modulates expression of HSP90.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Focal adhesion kinase regulation of N-WASP subcellular localization and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

Tyrosine phosphorylation of the Wiskott-Aldrich syndrome protein by Lyn and Btk is regulated by CDC42

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

7 January 2021

Quantitative analysis of the effect of Acanthamoeba profilin on actin filament nucleation and elongation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

7 January 2021

Evolutionary conservation of motif constituents in the yeast protein interaction network

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

7 January 2021

Exploration of the sequence specificity of pp60c-src tyrosine kinase. Minimal peptide sequence required for maximal activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

7 January 2021

Elucidation of binding determinants and functional consequences of Ras/Raf-cysteine-rich domain interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M509416200

7 January 2021