Beyond the cell cycle: a new role for Cdk6 in differentiation (Q24295941)

Cyclin dependent kinase 6

Europe PubMed Central

title

Beyond the cell cycle: a new role for Cdk6 in differentiation (English)

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main subject

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negative regulation of cell differentiation

GOA release 2020-03-11

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Journal of Cellular Biochemistry

GOA release 2020-03-11

author name string

Martha J Grossel

series ordinal

1

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Philip W Hinds

series ordinal

2

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language of work or name

English

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publication date

15 February 2006

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published in

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volume

97

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issue

3

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page(s)

485-93

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cites work

A family of human cdc2-related protein kinases

1 reference

7 January 2021

Differential regulation of the synthesis and activity of the major cyclin‐dependent kinases, p34cdc2, p33cdk2, and p34cdk4, during cell cycle entry and progression in normal human T lymphocytes

1 reference

7 January 2021

Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

1 reference

7 January 2021

TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest

1 reference

7 January 2021

Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

1 reference

7 January 2021

Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6

1 reference

7 January 2021

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

1 reference

7 January 2021

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

1 reference

7 January 2021

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

1 reference

7 January 2021

Transcriptional regulation by a cyclin-cdk

1 reference

7 January 2021

Id proteins in neural cancer.

1 reference

7 January 2021

Regulation of G(1) cyclin-dependent kinases in the mammalian cell cycle

1 reference

7 January 2021

p27Kip1 alters the response of cells to mitogen and is part of a cell-intrinsic timer that arrests the cell cycle and initiates differentiation.

1 reference

7 January 2021

Runx transcription factors and the developmental balance between cell proliferation and differentiation.

1 reference

7 January 2021

The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation

1 reference

7 January 2021

Radiation-induced cell cycle arrest compromised by p21 deficiency

1 reference

7 January 2021

Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome

1 reference

7 January 2021

The motor domain determines the large step of myosin-V.

1 reference

7 January 2021

Cyclin-dependent kinases regulate the antiproliferative function of Smads

1 reference

7 January 2021

Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma

1 reference

7 January 2021

Active cdk6 complexes are predominantly nuclear and represent only a minority of the cdk6 in T cells

1 reference

7 January 2021

The retinoblastoma gene family in differentiation and development.

1 reference

7 January 2021

Accumulation of high levels of the p53 and p130 growth-suppressing proteins in cell lines stably over-expressing cyclin-dependent kinase 6 (cdk6)

1 reference

7 January 2021

CDK6 blocks differentiation: coupling cell proliferation to the block to differentiation in leukemic cells

1 reference

7 January 2021

Runx2 control of organization, assembly and activity of the regulatory machinery for skeletal gene expression

1 reference

7 January 2021

Reprogramming leukemic cells to terminal differentiation by inhibiting specific cyclin-dependent kinases in G1.

1 reference

7 January 2021

The activation domain of transcription factor PU.1 binds the retinoblastoma (RB) protein and the transcription factor TFIID in vitro: RB shows sequence similarity to TFIID and TFIIB

1 reference

7 January 2021

cdk6 can shorten G(1) phase dependent upon the N-terminal INK4 interaction domain

1 reference

7 January 2021

p57Kip2 regulates actin dynamics by binding and translocating LIM-kinase 1 to the nucleus

1 reference

7 January 2021

p21Cip1 and p27Kip1 induce distinct cell cycle effects and differentiation programs in myeloid leukemia cells.

1 reference

7 January 2021

The p16(INK4a) tumour suppressor protein inhibits alphavbeta3 integrin-mediated cell spreading on vitronectin by blocking PKC-dependent localization of alphavbeta3 to focal contacts

1 reference

7 January 2021

The Id4 HLH protein and the timing of oligodendrocyte differentiation

1 reference

7 January 2021

Preferences for phosphorylation sites in the retinoblastoma protein of D-type cyclin-dependent kinases, Cdk4 and Cdk6, in vitro

1 reference

7 January 2021

Shared role of the pRB-related p130 and p107 proteins in limb development

1 reference

7 January 2021

Direct binding of cyclin D to the retinoblastoma gene product (pRb) and pRb phosphorylation by the cyclin D-dependent kinase CDK4

1 reference

7 January 2021

Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization

1 reference

7 January 2021

Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein

1 reference

7 January 2021

A p16INK4a-insensitive CDK4 mutant targeted by cytolytic T lymphocytes in a human melanoma

1 reference

7 January 2021

Cell biology. Cell cycle inhibitors may help brake growth as cells develop.

1 reference

7 January 2021

D-type cyclin-dependent kinase activity in mammalian cells

1 reference

7 January 2021

Identification of G1 kinase activity for cdk6, a novel cyclin D partner

1 reference

7 January 2021

Novel p27(kip1) C-terminal scatter domain mediates Rac-dependent cell migration independent of cell cycle arrest functions

1 reference

7 January 2021

Bone morphogenetic protein 2-induced osteoblast differentiation requires Smad-mediated down-regulation of Cdk6

1 reference

7 January 2021

Osteoclast differentiation by RANKL requires NF-kappaB-mediated downregulation of cyclin-dependent kinase 6 (Cdk6).

1 reference

7 January 2021

New perspectives on retinoblastoma family functions in differentiation.

1 reference

7 January 2021