The ATRX-ADD domain binds to H3 tail peptides and reads the combined methylation state of K4 and K9 (Q24297608)

methylated histone binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Albert Jeltsch

8

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author name string

Arunkumar Dhayalan

1

0 references

Raluca Tamas

2

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Ina Bock

3

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Anna Tattermusch

4

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Emilia Dimitrova

5

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Srikanth Kudithipudi

6

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Sergey Ragozin

Daxx is an H3.3-specific histone chaperone and cooperates with ATRX in replication-independent chromatin assembly at telomeres

7

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language of work or name

English

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publication date

1 June 2011

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published in

Human Molecular Genetics

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volume

20

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issue

11

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page(s)

2195-203

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cites work

1 reference

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Structural basis for recognition of H3K4 methylation status by the DNA methyltransferase 3A ATRX-DNMT3-DNMT3L domain

19 March 2017

1 reference

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DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA

19 March 2017

1 reference

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Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardation

19 March 2017

1 reference

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The ATRX syndrome protein forms a chromatin-remodeling complex with Daxx and localizes in promyelocytic leukemia nuclear bodies

19 March 2017

1 reference

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Localization of a putative transcriptional regulator (ATRX) at pericentromeric heterochromatin and the short arms of acrocentric chromosomes

19 March 2017

1 reference

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Cloning, expression and chromosome locations of the human DNMT3 gene family

19 March 2017

1 reference

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Mutations in a putative global transcriptional regulator cause X-linked mental retardation with alpha-thalassemia (ATR-X syndrome)

19 March 2017

1 reference

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The ankyrin repeat domain of Huntingtin interacting protein 14 contains a surface aromatic cage, a potential site for methyl-lysine binding

19 March 2017

1 reference

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Structural consequences of disease-causing mutations in the ATRX-DNMT3-DNMT3L (ADD) domain of the chromatin-associated protein ATRX

19 March 2017

1 reference

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Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail

19 March 2017

1 reference

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ATRX interacts with H3.3 in maintaining telomere structural integrity in pluripotent embryonic stem cells

19 March 2017

1 reference

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Distinct factors control histone variant H3.3 localization at specific genomic regions

19 March 2017

1 reference

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Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22.3, related to the cytosine-5-methyltransferase 3 gene family

19 March 2017

1 reference

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Specific interaction between the XNP/ATR-X gene product and the SET domain of the human EZH2 protein

19 March 2017

1 reference

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A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors

19 March 2017

1 reference

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How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers

19 March 2017

1 reference

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Detailed specificity analysis of antibodies binding to modified histone tails with peptide arrays

7 April 2017

1 reference

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Synthesis of peptide arrays using SPOT-technology and the CelluSpots-method

27 September 2017

1 reference

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PHD fingers in human diseases: disorders arising from misinterpreting epigenetic marks

27 September 2017

1 reference

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Protein lysine methyltransferase G9a acts on non-histone targets

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090196

Association of ATRX with pericentric heterochromatin and the Y chromosome of neonatal mouse spermatogonia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090196

Loss of Atrx affects trophoblast development and the pattern of X-inactivation in extraembryonic tissues

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090196

Mouse centric and pericentric satellite repeats form distinct functional heterochromatin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090196

Histone H3 lysine 9 methylation is an epigenetic imprint of facultative heterochromatin.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090196

ATR-X mutations cause impaired nuclear location and altered DNA binding properties of the XNP/ATR-X protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090196

Clinical and hematologic aspects of the X-linked alpha-thalassemia/mental retardation syndrome (ATR-X).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090196

Chromatin methylation activity of Dnmt3a and Dnmt3a/3L is guided by interaction of the ADD domain with the histone H3 tail

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090196

Comparison of the human and murine ATRX gene identifies highly conserved, functionally important domains.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090196

Mutations in the chromatin-associated protein ATRX.

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FHMG%2FDDR107

Mutations in PHD-like domain of the ATRX gene correlate with severe psychomotor impairment and severe urogenital abnormalities in patients with ATRX syndrome.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FHMG%2FDDR107

Analysis of epigenetic modifications of chromatin at specific gene loci by native chromatin immunoprecipitation of nucleosomes isolated using hydroxyapatite chromatography.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FHMG%2FDDR107

Site-directed mutagenesis by polymerase chain reaction

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090196

Extraction, purification and analysis of histones

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21421568

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/HMG/DDR107

1 reference

4098789

4098789

1 reference

1 reference

1 reference