Phosphorylation of focal adhesion kinase on tyrosine 194 by Met leads to its activation through relief of autoinhibition (Q24297931)

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C-L Chen

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H-C Chen

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language of work or name

English

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publication date

13 January 2011

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30 August 2010

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Europe PubMed Central

PubMed publication ID

20802513

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20802513

full work available at URL

3 July 2024

https://www.nature.com/articles/onc2010398.pdf

file format

Portable Document Format

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https://api.crossref.org/works/10.1038/ONC.2010.398

https://www.nature.com/articles/onc2010398

3 July 2024

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https://api.crossref.org/works/10.1038/ONC.2010.398

3 July 2024

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30

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issue

2

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page(s)

153-66

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cites work

Regulation of the PH-domain-containing tyrosine kinase Etk by focal adhesion kinase through the FERM domain

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Regulation of focal adhesion-associated protein tyrosine kinase by both cellular adhesion and oncogenic transformation

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Identification of sequences required for the efficient localization of the focal adhesion kinase, pp125FAK, to cellular focal adhesions

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https://api.crossref.org/works/10.1038/ONC.2010.398

Identification of major tyrosine phosphorylation sites in the human insulin receptor substrate Gab-1 by insulin receptor kinase in vitro

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Structural basis for the autoinhibition of focal adhesion kinase

20 April 2017

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https://api.crossref.org/works/10.1038/ONC.2010.398

pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

20 April 2017

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https://api.crossref.org/works/10.1038/ONC.2010.398

Focal adhesion kinase and paxillin bind to peptides mimicking beta integrin cytoplasmic domains

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FAK integrates growth-factor and integrin signals to promote cell migration

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Focal adhesion kinase: in command and control of cell motility

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Spatial and temporal regulation of focal adhesion kinase activity in living cells.

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https://api.crossref.org/works/10.1038%2FONC.2010.398

Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

21 January 2018

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Synergistic effect of focal adhesion kinase overexpression and hepatocyte growth factor stimulation on cell transformation

21 January 2018

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Tyrosine phosphorylation of focal adhesion kinase stimulated by hepatocyte growth factor leads to mitogen-activated protein kinase activation

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Direct interaction of focal adhesion kinase (FAK) with Met is required for FAK to promote hepatocyte growth factor-induced cell invasion

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.398

Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.398

Residues within the first subdomain of the FERM-like domain in focal adhesion kinase are important in its regulation.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.398

Regulation of focal adhesion kinase by its amino-terminal domain through an autoinhibitory interaction

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FERM domain interaction promotes FAK signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.398

Identification of Tyr-397 as the primary site of tyrosine phosphorylation and pp60src association in the focal adhesion kinase, pp125FAK.

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.398

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin

21 January 2018

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A truncated FAK lacking the FERM domain displays high catalytic activity but retains responsiveness to adhesion-mediated signals

21 January 2018

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Identification of tyrosine phosphorylation sites in human Gab-1 protein by EGF receptor kinase in vitro.

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The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

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Ezrin interacts with focal adhesion kinase and induces its activation independently of cell-matrix adhesion

21 January 2018

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Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2010.398

Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain

21 January 2018

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Focal adhesion kinase controls actin assembly via a FERM-mediated interaction with the Arp2/3 complex

21 January 2018

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Association of beta 1 integrin with focal adhesion kinase and paxillin in differentiating Schwann cells.

21 January 2018

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Involvement of focal adhesion kinase in hepatocyte growth factor-induced scatter of Madin-Darby canine kidney cells

31 March 2020

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Hepatocyte growth factor/scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125FAK) and promotes migration and invasion by oral squamous cell carcinoma cells

31 March 2020

https://api.crossref.org/works/10.1038/ONC.2010.398

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