Human paraoxonases (PON1, PON2, and PON3) are lactonases with overlapping and distinct substrate specificities (Q24298200)

ChEBI release 2020-05-28

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Paraoxonase 2

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Paraoxonase 3

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carboxylic acid catabolic process

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author name string

Dragomir I Draganov

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John F Teiber

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Audrey Speelman

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Yoichi Osawa

4

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Roger Sunahara

5

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Bert N La Du

Journal of Lipid Research

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language of work or name

English

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publication date

June 2005

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published in

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volume

46

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page(s)

1239-47

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issue

6

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cites work

The human serum paraoxonase/arylesterase gene (PON1) is one member of a multigene family

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Pharmacogenetics of paraoxonases: a brief review

21 January 2018

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The effect of the human serum paraoxonase polymorphism is reversed with diazoxon, soman and sarin

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Selective plasma hydrolysis of glucocorticoid gamma-lactones and cyclic carbonates by the enzyme paraoxonase: an ideal plasma inactivation mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Lactonase and lactonizing activities of human serum paraoxonase (PON1) and rabbit serum PON3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Rabbit serum paraoxonase 3 (PON3) is a high density lipoprotein-associated lactonase and protects low density lipoprotein against oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Identification of paraoxonase 3 in rat liver microsomes: purification and biochemical properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Mouse macrophage paraoxonase 2 activity is increased whereas cellular paraoxonase 3 activity is decreased under oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Characterization of cDNA clones encoding rabbit and human serum paraoxonase: the mature protein retains its signal sequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Human serum Paraoxonase/Arylesterase's retained hydrophobic N-terminal leader sequence associates with HDLs by binding phospholipids : apolipoprotein A-I stabilizes activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Human paraoxonase-3 is an HDL-associated enzyme with biological activity similar to paraoxonase-1 protein but is not regulated by oxidized lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Paraoxonase-2 is a ubiquitously expressed protein with antioxidant properties and is capable of preventing cell-mediated oxidative modification of low density lipoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Human PON2 gene at 7q21.3: cloning, multiple mRNA forms, and missense polymorphisms in the coding sequence

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Paraoxonase inhibits high-density lipoprotein oxidation and preserves its functions. A possible peroxidative role for paraoxonase

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Protective effect of high density lipoprotein associated paraoxonase. Inhibition of the biological activity of minimally oxidized low density lipoprotein

21 January 2018

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Paraoxonase and atherosclerosis

21 January 2018

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Functional genomic of the paraoxonase (PON1) polymorphisms: effects on pesticide sensitivity, cardiovascular disease, and drug metabolism

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis

21 January 2018

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

21 January 2018

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Molecular weights of protein multimers from polyacrylamide gel electrophoresis

21 January 2018

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Spectrophotometric assays for the enzymatic hydrolysis of the active metabolites of chlorpyrifos and parathion by plasma paraoxonase/arylesterase.

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Purified human serum PON1 does not protect LDL against oxidation in the in vitro assays initiated with copper or AAPH

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

A second N-acylhomoserine lactone signal produced by Pseudomonas aeruginosa

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Paraoxonase-1 does not reduce or modify oxidation of phospholipids by peroxynitrite.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Platelet-activating factor acetylhydrolase, and not paraoxonase-1, is the oxidized phospholipid hydrolase of high density lipoprotein particles

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Structural requirements for the inhibition of 5-lipoxygenase by 15-hydroxyeicosa-5,8,11,13-tetraenoic acid analogues

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Inhibition of platelet and neutrophil phospholipase A2 by hydroxyeicosatetraenoic acids (HETES). A novel pharmacological mechanism for regulating free fatty acid release

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Resolvins, docosatrienes, and neuroprotectins, novel omega-3-derived mediators, and their aspirin-triggered endogenous epimers: an overview of their protective roles in catabasis

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Lipoxins: potential anti-inflammatory, proresolution, and antifibrotic mediators in renal disease

21 January 2018

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Epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids are potent vasodilators in the canine coronary microcirculation.

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Communications blackout? Do N-acylhomoserine-lactone-degrading enzymes have any role in quorum sensing?

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

The Pseudomonas aeruginosa autoinducer N-3-oxododecanoyl homoserine lactone accelerates apoptosis in macrophages and neutrophils.

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Differential immune modulatory activity of Pseudomonas aeruginosa quorum-sensing signal molecules.

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Inactivation of a Pseudomonas aeruginosa quorum-sensing signal by human airway epithelia.

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

Modulation by hydroxyeicosatetraenoic acids (HETEs) of arachidonic acid metabolism in mouse resident peritoneal macrophages

21 January 2018

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

7 January 2021

Paraoxonase prevents accumulation of lipoperoxides in low-density lipoprotein

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

7 January 2021

STARCH-GEL ELECTROPHORESIS--APPLICATION TO THE CLASSIFICATION OF PITUITARY PROTEINS AND POLYPEPTIDES.

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

7 January 2021

Human serum paraoxonase (PON 1) is inactivated by oxidized low density lipoprotein and preserved by antioxidants

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https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

7 January 2021

Synthesis and 5-lipoxygenase inhibitory activity of 5-hydroperoxy-6,8,11,14-eicosatetraenoic acid analogues

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

7 January 2021

Hydrolysis of platelet-activating factor by human serum paraoxonase

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M400511-JLR200

7 January 2021

10.1194/JLR.M400511-JLR200

Identifiers

DOI

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Consolidated OpenCitations Corpus – April 2017

4184227

4184227

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

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