Structural and biochemical characterization of the folyl-poly-γ-l-glutamate hydrolyzing activity of human glutamate carboxypeptidase II (Q24298320)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257983&resulttype=core&format=json

13 May 2020

0 references

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1904492

tetrahydrofolyl-poly(glutamate) polymer binding

2 references

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1904493

glutamate carboxypeptidase II

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

7

Jan Konvalinka

Jan

Konvalinka

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257983&resulttype=core&format=json

13 May 2020

3

Pavel Šácha

Pavel

Šácha

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257983&resulttype=core&format=json

13 May 2020

6

Cyril Bařinka

Cyril

Bařinka

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257983&resulttype=core&format=json

13 May 2020

Michal Navrátil

1

Michal

Navrátil

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257983&resulttype=core&format=json

13 May 2020

Jakub Ptáček

series ordinal

2

author given names

Jakub

author last names

Ptáček

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257983&resulttype=core&format=json

13 May 2020

Jana Starková

series ordinal

4

author given names

Jana

author last names

Starková

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257983&resulttype=core&format=json

13 May 2020

Jacek Lubkowski

series ordinal

5

author given names

Jacek

author last names

Lubkowski

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257983&resulttype=core&format=json

13 May 2020

language of work or name

English

0 references

publication date

July 2014

0 references

published in

FEBS Journal

1 reference

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13 May 2020

volume

281

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257983&resulttype=core&format=json

13 May 2020

issue

14

1 reference

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13 May 2020

page(s)

3228-3242

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257983&resulttype=core&format=json

Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer

13 May 2020

cites work

1 reference

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Reaction mechanism of glutamate carboxypeptidase II revealed by mutagenesis, X-ray crystallography, and computational methods

21 January 2018

1 reference

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Glutamate carboxypeptidase II in diagnosis and treatment of neurologic disorders and prostate cancer

21 January 2018

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Glutamate carboxypeptidase II: an overview of structural studies and their importance for structure-based drug design and deciphering the reaction mechanism of the enzyme

21 January 2018

1 reference

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Polymorphisms in the one-carbon metabolic pathway, plasma folate levels and colorectal cancer in a prospective study

21 January 2018

1 reference

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A remote arene-binding site on prostate specific membrane antigen revealed by antibody-recruiting small molecules

21 January 2018

1 reference

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Structural insight into the pharmacophore pocket of human glutamate carboxypeptidase II

21 January 2018

1 reference

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Glutamate carboxypeptidase II: a polymorphism associated with lower levels of serum folate and hyperhomocysteinemia.

21 January 2018

1 reference

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Current and Novel Inhibitors of HIV Protease

21 January 2018

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Amino acids at the N- and C-termini of human glutamate carboxypeptidase II are required for enzymatic activity and proper folding.

21 January 2018

1 reference

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Hydrolysis of the neuropeptide N-acetylaspartylglutamate (NAAG) by cloned human glutamate carboxypeptidase II.

21 January 2018

1 reference

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Development of a high-throughput fluorescence polarization assay to identify novel ligands of glutamate carboxypeptidase II

21 January 2018

1 reference

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Folic acid and L-5-methyltetrahydrofolate: comparison of clinical pharmacokinetics and pharmacodynamics

21 January 2018

1 reference

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Structural basis for molecular recognition of folic acid by folate receptors

21 January 2018

1 reference

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Structural Basis of Interactions between Human Glutamate Carboxypeptidase II and Its Substrate Analogs

21 January 2018

1 reference

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Biochemical characterization of human glutamate carboxypeptidase III

21 January 2018

1 reference

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Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III

21 January 2018

1 reference

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Molecular identification of β-citrylglutamate hydrolase as glutamate carboxypeptidase 3

21 January 2018

1 reference

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Substrate specificity, inhibition and enzymological analysis of recombinant human glutamate carboxypeptidase II.

21 January 2018

1 reference

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Efficient and versatile one-step affinity purification of in vivo biotinylated proteins: Expression, characterization and structure analysis of recombinant human glutamate carboxypeptidase II

21 January 2018

1 reference

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OligoCalc: an online oligonucleotide properties calculator.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12857

A high-resolution structure of ligand-free human glutamate carboxypeptidase II

21 January 2018

1 reference

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Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

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Overview of the CCP4 suite and current developments

21 January 2018

1 reference

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Features and development of Coot

21 January 2018

1 reference

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PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

21 January 2018

1 reference

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MolProbity: all-atom structure validation for macromolecular crystallography

21 January 2018

1 reference

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Thermofluor-based high-throughput stability optimization of proteins for structural studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12857

XDSAPP: a graphical user interface for the convenient processing of diffraction data usingXDS

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FFEBS.12857

Prostate-specific membrane antigen: a novel folate hydrolase in human prostatic carcinoma cells

21 January 2018

1 reference

12 December 2020

The glutamate carboxypeptidase gene II (C>T) polymorphism does not affect folate status in the Framingham Offspring cohort

1 reference

12 December 2020

Hydrolysis of the brain dipeptide N-acetyl-L-aspartyl-L-glutamate. Identification and characterization of a novel N-acetylated alpha-linked acidic dipeptidase activity from rat brain.

1 reference

12 December 2020

Interactions among polymorphisms in folate-metabolizing genes and serum total homocysteine concentrations in a healthy elderly population

1 reference

12 December 2020

Relations of glutamate carboxypeptidase II (GCPII) polymorphisms to folate and homocysteine concentrations and to scores of cognition, anxiety, and depression in a homogeneous Norwegian population: the Hordaland Homocysteine Study

1 reference

12 December 2020

Molecular cloning of a complementary DNA encoding a prostate-specific membrane antigen

1 reference

12 December 2020

Fluorescence reaction for amino acids

1 reference

12 December 2020

Combined impact of polymorphism of folate metabolism genes; glutamate carboxypeptidase, methylene tetrahydrofolate reductase and methionine synthase reductase on breast cancer susceptibility in kashmiri women.

1 reference

12 December 2020

Identifiers

DOI

10.1111/FEBS.12857

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257983&resulttype=core&format=json

release_77via4mavja53gil4bhzonxsr4

13 May 2020

Fatcat ID

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6257983&resulttype=core&format=json

13 May 2020

PubMed publication ID

24863754

1 reference