Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations (Q24298328)

negative regulation of pro-B cell differentiation

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

Notch 1

1 reference

A mammalian helix-loop-helix factor structurally related to the product of Drosophila proneural gene atonal is a positive transcriptional regulator expressed in the developing nervous system.

GOA release 2020-03-11

1 reference

Shin Kawamata

1

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Changchun Du

series ordinal

2

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Kaijun Li

series ordinal

3

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Catherine Lavau

series ordinal

4

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language of work or name

English

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publication date

30 May 2002

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published in

Oncogene

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volume

21

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page(s)

3855-63

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issue

24

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cites work

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Notch signaling: cell fate control and signal integration in development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

E2A proteins are required for proper B cell development and initiation of immunoglobulin gene rearrangements

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Ectopic TAL-1/SCL expression in phenotypically normal or leukemic myeloid precursors: proliferative and antiapoptotic effects coupled with a differentiation blockade

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Correlating notch signaling with thymocyte maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Generation of structurally and functionally distinct factors from the basic helix-loop-helix gene Hes3 by alternative first exons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Molecular characterization of HES-2, a mammalian helix-loop-helix factor structurally related to Drosophila hairy and Enhancer of split

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Delta-1 activation of notch-1 signaling results in HES-1 transactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

A role for pref-1 and HES-1 in thymocyte development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Activation of OX40 signal transduction pathways leads to tumor necrosis factor receptor-associated factor (TRAF) 2- and TRAF5-mediated NF-kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

The notch pathway intermediate HES-1 silences CD4 gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Constitutively active human Notch1 binds to the transcription factor CBF1 and stimulates transcription through a promoter containing a CBF1-responsive element

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Helix-loop-helix proteins: regulators of transcription in eucaryotic organisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

The mammalian basic helix loop helix protein HES-1 binds to and modulates the transactivating function of the runt-related factor Cbfa1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Inhibition of granulocytic differentiation by mNotch1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Structure, chromosomal locus, and promoter of mouse Hes2 gene, a homologue of Drosophila hairy and Enhancer of split

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Hes1 and Hes5 as notch effectors in mammalian neuronal differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Notch inhibition of E47 supports the existence of a novel signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Notch and the immune system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

NF-kappaB2 is a putative target gene of activated Notch-1 via RBP-Jkappa

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Notch1 expression in early lymphopoiesis influences B versus T lineage determination.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

An activated form of Notch influences the choice between CD4 and CD8 T cell lineages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

The notch intracellular domain can function as a coactivator for LEF-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Notch signalling via RBP-J promotes myeloid differentiation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

T cell development in the adult murine thymus: changes in the expression of the surface antigens Ly2, L3T4 and B2A2 during development from early precursor cells to emigrants

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

The oncogenic capacity of HRX-ENL requires the transcriptional transactivation activity of ENL and the DNA binding motifs of HRX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

The bHLH gene Hes1 is essential for expansion of early T cell precursors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Notch activity influences the alphabeta versus gammadelta T cell lineage decision

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487

Inactivation of Notch 1 in immature thymocytes does not perturb CD4 or CD8T cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205487