Human CWC22 escorts the helicase eIF4AIII to spliceosomes and promotes exon junction complex assembly (Q24298426)

Eukaryotic translation initiation factor 4A3

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Uncharacterized protein Dmel_CG7483

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Nucampholin Dmel_CG12750

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Hervé Le Hir

7

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Catherine Tomasetto

object named as

Catherine Tomasetto

5

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author name string

Isabelle Barbosa

1

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Nazmul Haque

2

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Francesca Fiorini

3

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Charlotte Barrandon

4

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Marco Blanchette

Nature Structural & Molecular Biology

6

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language of work or name

English

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publication date

October 2012

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published in

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volume

19

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page(s)

983-90

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issue

10

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cites work

The spliceosome deposits multiple proteins 20-24 nucleotides upstream of mRNA exon-exon junctions

1 reference

Structure of the exon junction core complex with a trapped DEAD-box ATPase bound to RNA

20 April 2017

1 reference

The exon junction core complex is locked onto RNA by inhibition of eIF4AIII ATPase activity

20 April 2017

1 reference

The crystal structure of the exon junction complex reveals how it maintains a stable grip on mRNA

20 April 2017

1 reference

SF1 and SF2 helicases: family matters

20 April 2017

1 reference

Mechanism of ATP turnover inhibition in the EJC

20 April 2017

1 reference

Disassembly of exon junction complexes by PYM

20 April 2017

1 reference

The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling

20 April 2017

1 reference

Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators

20 April 2017

1 reference

How and where are nonsense mRNAs degraded in mammalian cells?

20 April 2017

1 reference

The EJC factor eIF4AIII modulates synaptic strength and neuronal protein expression

20 April 2017

1 reference

The spliceosome: design principles of a dynamic RNP machine

20 April 2017

1 reference

Purification and characterization of native spliceosomes suitable for three-dimensional structural analysis

20 April 2017

1 reference

Splicing remodels messenger ribonucleoprotein architecture via eIF4A3-dependent and -independent recruitment of exon junction complex components

20 April 2017

1 reference

Biochemical analysis of the EJC reveals two new factors and a stable tetrameric protein core

20 April 2017

1 reference

Characterization of interactions among the Cef1p-Prp19p-associated splicing complex

20 April 2017

1 reference

Splicing factor Cwc22 is required for the function of Prp2 and for the spliceosome to escape from a futile pathway

20 April 2017

1 reference

Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex

20 April 2017

1 reference

Mutational analysis of human eIF4AIII identifies regions necessary for exon junction complex formation and nonsense-mediated mRNA decay

20 April 2017

1 reference

RNA helicases at work: binding and rearranging

20 April 2017

1 reference

Human eIF4AIII interacts with an eIF4G-like partner, NOM1, revealing an evolutionarily conserved function outside the exon junction complex

20 April 2017

1 reference

Eukaryotic initiation factor 4a3 is a selenium-regulated RNA-binding protein that selectively inhibits selenocysteine incorporation

20 April 2017

1 reference

Topology and regulation of the human eIF4A/4G/4H helicase complex in translation initiation

20 April 2017

1 reference

A conserved mechanism of DEAD-box ATPase activation by nucleoporins and InsP6 in mRNA export

20 April 2017

1 reference

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

20 April 2017

1 reference

The deubiquitylation activity of Ubp8 is dependent upon Sgf11 and its association with the SAGA complex

20 April 2017

1 reference

Molecular mechanisms for the RNA-dependent ATPase activity of Upf1 and its regulation by Upf2

20 April 2017

1 reference

Pre-mRNA processing reaches back to transcription and ahead to translation

20 April 2017

1 reference

The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay

20 April 2017

1 reference

The ever-increasing complexities of the exon junction complex

20 April 2017

1 reference

Structural insights into the exon junction complex

31 March 2020

1 reference

The Y14 protein communicates to the cytoplasm the position of exon-exon junctions

31 March 2020

1 reference

The exon junction complex controls the splicing of MAPK and other long intron-containing transcripts in Drosophila

31 March 2020

1 reference

Exon junction complex subunits are required to splice Drosophila MAP kinase, a large heterochromatic gene

31 March 2020

1 reference

Splicing of oskar RNA in the nucleus is coupled to its cytoplasmic localization

31 March 2020

1 reference

EJCs at the heart of translational control

31 March 2020

1 reference

Execution of nonsense-mediated mRNA decay: what defines a substrate?

31 March 2020

1 reference

Nonsense-mediated mRNA decay (NMD) in animal embryogenesis: to die or not to die, that is the question

31 March 2020

1 reference

The exon junction complex differentially marks spliced junctions

31 March 2020

1 reference

The exon junction complex component Magoh controls brain size by regulating neural stem cell division.

31 March 2020

1 reference

Isolation of an active step I spliceosome and composition of its RNP core.

31 March 2020

1 reference

Small nuclear ribonucleoprotein remodeling during catalytic activation of the spliceosome.

31 March 2020

1 reference

Protein composition of human mRNPs spliced in vitro and differential requirements for mRNP protein recruitment

31 March 2020

1 reference

5' exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly

31 March 2020

1 reference

Association of the breast cancer protein MLN51 with the exon junction complex via its speckle localizer and RNA binding module

31 March 2020

1 reference

The hierarchy of exon-junction complex assembly by the spliceosome explains key features of mammalian nonsense-mediated mRNA decay

31 March 2020

1 reference

Perispeckles are major assembly sites for the exon junction core complex

31 March 2020

1 reference

In vivo recruitment of exon junction complex proteins to transcription sites in mammalian cell nuclei

31 March 2020

1 reference

In vivo BiFC analysis of Y14 and NXF1 mRNA export complexes: preferential localization within and around SC35 domains

31 March 2020

1 reference

Molecular anatomy of a speckle

31 March 2020

1 reference

Eukaryotic translation initiation factor 4AIII (eIF4AIII) is functionally distinct from eIF4AI and eIF4AII

31 March 2020

1 reference

NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity

31 March 2020

1 reference

ATP utilization and RNA conformational rearrangement by DEAD-box proteins

31 March 2020

1 reference

From unwinding to clamping - the DEAD box RNA helicase family

31 March 2020

1 reference

eIF4G stimulates the activity of the DEAD box protein eIF4A by a conformational guidance mechanism

31 March 2020

1 reference

Introns play an essential role in splicing-dependent formation of the exon junction complex.

31 March 2020

1 reference

A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release

31 March 2020

1 reference

A novel set of spliceosome-associated proteins and the essential splicing factor PSF bind stably to pre-mRNA prior to catalytic step II of the splicing reaction

31 March 2020

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22961380

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Distinct requirements for somatic and germline expression of a generally expressed Caernorhabditis elegans gene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22961380

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NSMB.2380

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

4401212

1016948542

0 references

4401212

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference